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Appendix C

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Table 1. PKU vs Unaffected Control Participants on Various Outcomes

Note. N=number of effect sizes. Ratings=ratings of general behavior by parents/teachers, and self-concept. A positive effect size reflects a result in which the PKU group performed more poorly than the control group, on average.

Outcome N M d 95% Confidence Interval
IQ 63 0.3819 0.2799 to 0.4839
FSIQ 32 0.4258 0.2657 to 0.5859
VIQ 12 0.3230 0.0754 to 0.5706
PIQ 13 0.4401 0.1712 to 0.7090
Executive functions 37 0.4683 0.2316 to 0.7049
Inhibition and flexibility 31 0.3421 0.0902 to 0.5940
Attention 31 0.6575 0.4339 to 0.8811
Sustained and selective 22 0.6345 0.2993 to 0.9697
Behavior 131 0.1299 0.0666 to 0.1932
Ratings 85 0.1599 0.0794 to 0.2403
Psychological disorders 45 0.0735 -0.0333 to 0.1804
Other cognitive and motor skills 105 0.5033 0.3707 to 0.6360
Memory 6 0.3634 -0.2898 to 1.0167
Visual-spatial 18 1.3443 0.8540 to 1.8346
Motor 49 0.3656 0.2754 to 0.4557
Speed of processing 28 0.5293 0.0644 to 0.9943

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Last Updated Date: 08/29/2006
Last Reviewed Date: 08/29/2006
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology