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Fragile X-Associated Tremor and Ataxia Syndrome (FXTAS): Overview

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Fragile X-associated tremor and ataxia syndrome (FXTAS) is a late-onset condition (occurs in people older than age 50) that develops in some men and women with an altered form of the fragile X gene. Those with FXTAS do not have the intellectual or developmental disabilities common in fragile X syndrome.

NICHD-supported researchers were the first to identify FXTAS and link it to changes in the FMR1 gene, which causes fragile X syndrome. The Institute is one of several federal agencies working to understand FXTAS and other conditions caused by changes in the FMR1 gene. 

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Common Name

  • Fragile X-associated tremor and ataxia syndrome (FXTAS)

Medical or Scientific Name

  • FXTAS (pronounced FAX-tass)
Last Updated Date: 04/03/2013
Last Reviewed Date: 04/03/2013