The MPIDB, formerly the Pediatric, Adolescent, and Maternal AIDS Branch, was formed in 1988 with the mission to support and conduct domestic and international research related to the epidemiology, diagnosis, clinical manifestations, pathogenesis, transmission, treatment, and prevention of HIV infection and its complications in infants, children, adolescents, and women (pregnant and non-pregnant). As the HIV epidemic has evolved in the United States and globally, the MPIDB has ensured that research funded by the Branch reflects these changes and addresses important research opportunities and gaps as they arise. The research gaps in children and pregnant women related to many HIV-associated co-infections, such as tuberculosis, hepatitis, and malaria, have become evident as HIV research has become increasingly global in nature. The MPIDB has responded accordingly by promoting and funding new research related to these infectious pathogens in HIV-infected and -uninfected populations. In addition to HIV and associated infectious diseases, the MPIDB supports and conducts research into the epidemiology, natural history, pathogenesis, transmission, treatment, and prevention of other important infectious diseases, including congenital infections such as cytomegalovirus and toxoplasmosis; tropical diseases specifically affecting children and pregnant women; and vaccine-preventable disease in infants, children, adolescents, and women.
The Branch collaborates with other NICHD Branches, NIH Institutes, federal agencies such as the Centers for Disease Control and Prevention (CDC), the President's Emergency Plan for AIDS Relief (PEPFAR), and interested private organizations that share a focus on maternal, pediatric, and adolescent HIV infection and related infectious diseases. The Branch's activities target the following goals:
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