The DER provides funding and training support to some of the best scientific minds around the world.
Division of Extramural Research (DER) Organization Chart
The DER develops, implements, and coordinates cross-cutting, multidisciplinary research activities within the NICHD's mission, including efforts that focus on: demography, social sciences, and population dynamics; male and female fertility and infertility; developing and evaluating contraceptive methods; improving the safety and efficacy of pharmaceuticals for use in pregnant women, infants, and children; HIV infection and transmission, AIDS, and associated infections; pediatric growth and endocrine research; child development and behavior; developmental biology and typical and atypical development; intellectual and developmental disabilities; gynecologic health conditions, including pelvic floor disorders; and childhood injury and critical illness.
The DER also coordinates Institute research and training grant programs and advises the NICHD Director on extramural research and training policies and activities. The Division relies on its staff to represent the Institute on various trans-NIH and other collaborative workgroups and committees, to liaise with members of the Institute's federal advisory committees and boards, and to lead implementation of extramural policies and procedures for the NICHD.
The Division also performs grants management and scientific review functions, including conducting initial scientific merit review of grant applications and contract proposals for the NICHD. With a focus on scientific expertise, the DER also develops and supports extramural staff training while enhancing communication about standardized procedures, policies, methods, and approaches across the Institute.
The DER combines the functions of and Branches within the former Center for Developmental Biology and Perinatal Research, Center for Population Research, and Center for Research for Mothers and Children.
Visit with NICHD researchers at the 44th Annual Society for Neuroscience Meeting in Washington, DC, November 15–19, 2014. You can find the NICHD kiosk within the main NIH exhibit booth in the Institute/Government Agency section of the exhibit hall.
- New Treatment for Anovulatory Infertility in Polycystic Ovary Syndrome (PCOS)
PCOS is the most common cause of infertility in women who don’t ovulate. Doctors often use a drug called clomiphene citrate to stimulate ovulation in women with PCOS, but it had a low success rate along with some side effects like mood changes and hot flashes. The Fertility and Infertility Branch-supported Reproductive Medicine Network ran a clinical trial to compare the use of clomiphene citrate and another drug called letrozole, to treat infertility in women with PCOS. The drugs work differently: clomiphene changes the function of estrogen receptors, while letrozole inhibits the enzyme aromatase, which converts androgens to estrogens. In their study published in the New England Journal of Medicine, they reported that women with PCOS who took letrozole over 5 menstrual cycles were more likely to ovulate and had 44% more live births then women who took clomiphene. Letrozole was also just as safe to mothers and babies as clomiphene. This study shows that letrozole is superior to clomiphene in treating anovulatory women with PCOS. (PMID: 25006718 or see the press release at http://www.nichd.nih.gov/news/releases/Pages/070914-PCOS.aspx )
- Article: Ellen JM, Kapogiannis B, Fortenberry JD, Xu J, Willard N, DuVal A, Pace J, Loeb J, Monte D, Bethel J, and the Adolescent Medicine Trials Network. HIV Viral Load Levels and CD4 Cell Counts of Youth at Entry to HIV Care in Fourteen U.S. Cities. AIDS, 2014 May 15;28(8):1213-9.
- Joint project: Funded by the Child Development and Behavior Branch and the Population Dynamics Branch: School Retention and Health in Uganda (includes video)
- NICHD Scientific Vision
Scientific Vision: The Next Decade sets an ambitious agenda and inspires the NICHD, its many partners, and the research community to achieve critical scientific goals and meet pressing public health needs. Read the Scientific Vision.