Eunice Kennedy Shriver National Institute of Child Health and
Human Development (NICHD) Scientific Vision
Reproduction Workshop
Bethesda, MD
January 25-26, 2011

Views expressed in the workshop presentations are those of the
presenters alone and do not necessarily reflect those of the NICHD.


7:30 a.m. Registration and Breakfast
8:00 a.m. Welcome/NICHD Visioning Process (PDF - 1.29 MB)
Alan Guttmacher, M.D.
Director, NICHD
8:15 a.m. Workshop Overview and Introduction
Linda Giudice, M.D., Ph.D.
University of California, San Francisco (UCSF)
Regine Sitruk-Ware, M.D.
Population Council
8:30 a.m. Epidemiology of Male and Female Reproductive Disorders and Impact on Fertility Regulation and Population Growth (PDF - 690 KB)
Kurt T. Barnhart, M.D.
Professor, Department of Obstetrics & Gynecology
University of Pennsylvania
9:00 a.m. Questions
9:10 a.m. Steroid Hormones and the Human Reproductive System (PDF - 402 KB)
Bert W. O'Malley, M.D.
Professor and Chair, Department of Molecular and Cellular Biology
Baylor College of Medicine
9:40 a.m. Questions
9:50 a.m. Developmental Genetics and Innovative Technologies for the Diagnosis and Treatment of Infertility  (PDF - 2.68 MB)
Renee Reijo-Pera, Ph.D.
Professor of Obstetrics and Gynecology
Director, Center for Human Embryonic Stem Cell Research and Education
Stanford University
10:20 a.m. Questions
10:30 a.m. Break
10:45 a.m. Male Reproductive System: How Understanding Male Infertility Can Benefit Male Contraceptive Development (PDF - 2.89 MB)
Dolores J. Lamb, Ph.D.
Professor, Department of Urology
Baylor College of Medicine
11:15 a.m. Questions

Summary of Morning Discussion (PDF - 171 KB)
11:25 a.m. Presentation of Breakout Topics/Scientific Opportunities and Charge to Participants
Linda Giudice, M.D., Ph.D.
Regine Sitruk-Ware, M.D.
  • Group 1: Diagnostics and Treatments for Reproductive Diseases/Disorders
    Co-leaders: Marcelle Cedars, M.D. (UCSF); Catherine Racowsky, Ph.D., H.C.D. (Harvard University); and Teresa Woodruff, Ph.D. (Northwestern University)
    Develop novel diagnostics and treatments (both Assistive Reproduction Technologies [ART] and non-ART) for conditions/disorders that impact fertility and fecundity in males and females by advancing fundamental knowledge in reproductive biology and genetics, reproductive developmental biology and reproductive medicine, as well as applying advances in technology development and bioinformatics.
  • Group 2: Pre/Periconceptual Health and Pregnancy Establishment
    Co-leaders: Jerry Strauss, M.D., Ph.D. (Virginia Commonwealth University); Kelle Moley, M.D. (Washington University)
    Advance fundamental knowledge of pre/periconceptual health in females and males, as well as processes leading to pregnancy establishment (e.g., fertilization, implantation) with the goal of improving pregnancy outcomes.
  • Group 3: Contraception
    Co-leaders: Phil Darney, M.D., M.Sc. (UCSF); Greg Kopf, Ph.D. (Kansas University)
    Reduce the burden of unintended and unwanted pregnancies through fundamental and applied research resulting in newly developed and improved existing contraceptive methods in males and females, and ensure the acceptability and effective use of these products in various settings.
  • Group 4: Developmental Antecedents of Adult Reproductive Diseases/Disorders
    Co-leaders: Robert Rosenfield, M.D. (University of Chicago); Kjersti Aagaard-Tillery, M.D., Ph.D. (Baylor College of Medicine)
    Reduce the incidence of adult male and female reproductive diseases/disorders through a better understanding of early developmental processes in children, normal puberty, menstrual cycle dynamics in female adolescents and impact of altered nutrition on reproductive function.
  • Group 5: Quality-of-Life Improvements
    Co-leaders: Susan Rosenthal, Ph.D. (Columbia University); Elizabeth Stewart, M.D. (Mayo Clinic)
    Provide opportunities for quality-of-life improvements for women with gynecological diseases and reproductive tract disorders by developing novel approaches to diagnosing and treating and eventually ameliorating co-morbid conditions such as infertility, metabolic dysfunction, chronic pain and mood disorders.
  • Group 6: Reproductive Health as a Window to Overall Health
    Co-leaders: Paul Turek, M.D. (The Turek Clinic); Rick Legro, M.D. (Penn State University)
    Understand reproductive health in females and males and the menstrual cycle in females as windows to overall health.
12:00 p.m. Lunch
1:00 p.m. Breakout Discussions
3:00 p.m. Break
3:15 p.m. Breakout Discussions Continue
6:00 p.m. Dinner
7:00 p.m. Breakout Groups Prepare Presentations
9:00 p.m. Adjourn

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7:30 a.m. Continental Breakfast
8:00 a.m. Presentations by Breakout Leaders (PDF - 537 KB) (6 groups: ~10 minutes per presentation)
10:00 a.m. Break and Check-out
10:30 a.m. Discussion and Recommendations
12:00 p.m. Adjourn

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Last Reviewed: 03/17/2011