Bsx
Crx
Lhx4
Lhx9
NeuroD1
Otx2
Pax4
Pax6

Radiochemical in situ hybridization images of sections of the rat brain through the pineal gland.

Bsx

From: Carstensen MB, Hertz H, Bering T, Møller M, Rohde K, Klein DC, Coon SL, Rath MF . Circadian regulation and molecular role of the Bsx homeobox gene in the adult pineal gland. J. Pineal Res. 2020 Mar;68(2):e12629. doi: 10.1111/jpi.12629.

Crx

Crx E16

Crx E17

Crx E18

Crx E19

Crx E20

Crx E21

Crx P2

Crx P6

Crx P12

Crx P18

Crx P30

From Rath MF, Muñoz E, Ganguly S, Morin F, Shi Q, Klein DC, Moller M. Expression of the Otx2 homeobox gene in the developing mammalian brain: embryonic and adult expression in the pineal gland. J Neurochem. 2006 Apr;97(2):556-66. Epub 2006 Mar 15. PMID: 16539656 [PubMed - indexed for MEDLINE]

Lhx4

From: Hertz H, Carstensen MB, Bering T, Rohde K1, Møller M, Granau A, Coon SL, Klein DC, Rath MF . The Lhx4 homeobox transcript in the rat pineal gland: Adrenergic regulation and impact on transcripts encoding melatonin-synthesizing enzymes. J Pineal Res. 2020 Jan;68(1):e12616. doi: 10.1111/jpi.12616.

Lhx9

From: Yamazaki F, Møller M, Fu C, Clokie SJ, Zykovich A, Coon SL, Klein DC, Rath MF. The Lhx9 homeobox gene controls pineal gland development and prevents postnatal hydrocephalus. Brain Struct Funct. 2015;220(3):1497-509. doi: 10.1SL0 07/s00429-014-0740-x.

NeuroD1

NeuroD1 E16

NeuroD1 E17

NeuroD1 E18

NeuroD1 E19

NeuroD1 E20

NeuroD1 E21

NeuroD1 P2

NeuroD1 P6

NeuroD1 P12

NeuroD1 P18

NeuroD1 P30

From Muñoz, E.M. Bailey, M.J., Rath, M.F. Shi, Q., Morin, F., Coon, S. L., Møller, M. and Klein, D.C. , (2007) NeuroD1: developmental expression and regulated genes in the rodent pineal gland Neurochemistry, J. Neurochem. (2007) 10.1111/j.1471-4159.2007.04605.x

Otx2

Otx2 E16

Otx2 E17

Otx2 E18

Otx2 E19

Otx2 E20

Otx2 E21

Otx2 P2

Otx2 P6

Otx2 P12

Otx2 P18

Otx2 P30

From Rath MF, Muñoz E, Ganguly S, Morin F, Shi Q, Klein DC, Moller M. Expression of the Otx2 homeobox gene in the developing mammalian brain: embryonic and adult expression in the pineal gland. J Neurochem. 2006 Apr;97(2):556-66. Epub 2006 Mar 15. PMID: 16539656 [PubMed - indexed for MEDLINE]

Pax4

Pax4 E16

Pax4 E17

Pax4 E18

Pax4 E19

Pax4 E20

Pax4 E21

Pax4 P2

Pax4 P6

Pax4 P12

Pax4 P18

Pax4 P30

From Rath, M.F., Bailey, M.J., Kim, J.-S. Ho, A. K. Gaildrat, P., Coon, S.L. Møller, M. and Klein, D.C.(2008) Developmental and diurnal dynamics of Pax4 expression in the mammalian pineal gland: Nocturnal down-regulation is mediated by adrenergic-cyclic AMP signaling. Endocrinology, Rapid Electronic Publication first published on Sep 25, 2008 as doi:doi:10.1210/en.2008-0882

Pax6

Pax6 E16

Pax6 E17

Pax6 E18

Pax6 E19

Pax6 E20

Pax6 E21

Pax6 P2

Pax6 P6

Pax6 P12

Pax6 P18

Pax6 P30

From Rath, M.F., Bailey, M.J., Kim, J.-S. Ho, A. K. Gaildrat, P., Coon, S.L. Møller, M. and Klein, D.C.(2008)  Developmental and diurnal dynamics of Pax4 expression in the mammalian pineal gland: Nocturnal down-regulation is mediated by adrenergic-cyclic AMP signaling. Endocrinology, Rapid Electronic Publication first published on Sep 25, 2008 as doi:doi:10.1210/en.2008-0882