Current Research

• Roy et al. PIP5K1C phosphoinositide kinase deficiency distinguishes PIKFYVE-dependent cancer cells from non-malignant cells, Autophagy (2023) Mar 22:1‑21. PMID: 36803256.
• Logue et al. PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19, Commun Biol. (2022) 5(1):808. PMID: 35962188.
• Chakraborty et al. Selective elimination of pluripotent stem cells by PIKfyve specific inhibitors, Stem Cell Reports. (2022) 17(2):397‑412. PMID: 35063131.
• O'Connell and Vassilev. Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells, Cancer Res. (2021) 81(11):2903‑2917. PMID: 33685990.
• Sharma et al. A family of PIKFYVE inhibitors with therapeutic potential against autophagy‑dependent cancer cells disrupt multiple events in lysosome homeostasis, Autophagy (2019) (10):1694‑1718. PMID: 30806145.

Total Publications - A complete listing of 225 publications organized into categories

Chemistry

Bacterial Structure and Physiology

Enzymology

DNA Replication and Animal Viruses

Chromatin Structure

DNA Replication and Gene Expression in Mammalian Embryos

DNA Replication in Mammalian Chromosomes

Autophagy, Cancer

Reviews

Books

My National Center for Biotechnology Information (NCBI) Collection