The increase in pregnancy complications linked to air pollution exposure could result from the pollutants’ direct effects on the placenta, suggests a study in mice funded by the National Institutes of Health. Placentas of mice exposed to a mixture of common urban air pollutants before and during pregnancy were inflamed and had a loss of blood vessel cells. The study authors say the findings could provide insight into how air pollution might affect pregnancies and lead to strategies for preventing pregnancy complications.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Science Update: Pre-pregnancy obesity may increase child asthma risk, NIH study suggests
Maternal obesity before pregnancy may increase the risk of asthma in early childhood, suggests a study by the National Institutes of Health. Children born to mothers with obesity were more likely than those born to mothers without obesity to have persistent wheezing, an indication of asthma.
Science Update: Placental genetic material in maternal blood could potentially diagnose gestational diabetes early, small NIH-funded study suggests
A new method to detect genetic material from the placenta in the blood of pregnant people could potentially identify the risk for gestational, or pregnancy-related, diabetes in the first trimester, suggests a small study funded by the National Institutes of Health.
Science Update: NIH-funded researchers develop non-surgical method to treat endometriosis
Technique adapted from cancer treatment shows promise in mouse study.
Spotlight: Small Business Success Stories
NICHD-funded small business programs have led to innovations for patients, healthcare providers, researchers, and more. Learn about these success stories.
Science Update: NIH-funded researchers develop prototype genetic test to predict women’s risk for fibroids
Researchers funded by the National Institutes of Health have developed a prototype genetic test with the potential to predict the development and eventual severity of uterine fibroids—benign, but sometimes painful and debilitating tumors of the uterus. The test could be used to identify fibroid cases early and to better understand how they develop and how to treat them.
Science Update: Maternal pregnancy complications may increase risk of infant health effects, NIH-funded study suggests
Life-threatening pregnancy complications known as severe maternal morbidity (SMM) appear to be associated with an increased length of hospital stay for infants and an increase in the cost of caring for them, suggests a study funded by the National Institutes of Health. The findings support the hypothesis that infants of mothers with SMM may also be at risk for severe complications. The authors concluded that helping patients to reduce their risk factors—in early pregnancy or before conception—may reduce the chances for SMM and improve the health of infants.
Release: NIH-funded study suggests COVID-19 increases risk of pregnancy complications
Pregnant women with COVID-19 appear to be at greater risk for common pregnancy complications—in addition to health risks from the virus—than pregnant women without COVID-19, suggests a study funded by the National Institutes of Health.
Science Update: Children born during pandemic may experience slight neurodevelopmental delays, NIH-funded study suggests
Infants born during the pandemic—regardless of whether their mothers had COVID-19 during pregnancy—scored slightly lower on certain tests of neurodevelopment at 6 months old, compared to a similar group of infants born before the pandemic, according to a study funded by the National Institutes of Health. The findings suggest that children born during the pandemic may need long-term monitoring to rapidly identify any future lags in development. The researchers theorized that maternal stress resulting from the pandemic could have effects on children’s neurodevelopment.
Science Update: Weight loss before infertility treatment does not improve live birth rate in unexplained infertility, NIH-funded study suggests
A new study funded by the National Institutes of Health contradicts the current recommendation that women with obesity should lose weight before trying to conceive. The study of more than 300 women with obesity found no difference in the proportion of live births among women with unexplained infertility who lost weight before infertility treatment and a similar group who did not lose weight before treatment.
Release: COVID-19 vaccination does not reduce chances of conception, study suggests
COVID-19 vaccination does not affect the chances of conceiving a child, according to a study of more than 2,000 couples that was funded by the National Institutes of Health. Researchers found no differences in the chances of conception if either male or female partner had been vaccinated, compared to unvaccinated couples. However, couples had a slightly lower chance of conception if the male partner had been infected with SARS-CoV-2 within 60 days before a menstrual cycle, suggesting that COVID-19 could temporarily reduce male fertility.
Spotlight: Selected NICHD Research Advances of 2021
Read about NICHD’s research findings and activities from 2021.
Director's Corner: Celebrating NICHD’s 60th Anniversary
As we ring in the new year, 2022 marks a special milestone—the 60th anniversary of NICHD.
Release: COVID-19 vaccination associated with a small, temporary increase in menstrual cycle length, suggests NIH-funded study
Women receiving one dose of a COVID-19 vaccine during a single menstrual cycle had an increase in cycle length of nearly one day, according to an NIH-funded study.
Release: NIH study suggests women with disabilities have higher risk of birth complications and death
Pregnant women with disabilities have a much higher risk for severe pregnancy- and birth-related complications and death than other pregnant women, according to findings by researchers at the National Institutes of Health. Appearing in JAMA Network Open, the analysis of more than 223,000 deliveries in 19 U.S. hospitals found that roughly 2,199 women had a disability.
Item of Interest: PregSource® Mobile App Allows Access from Anywhere
It just got easier to participate in the PregSource®: Crowdsourcing to Understand Pregnancy research project. The free app allows participants to track their weight, sleep, mood, and other features of their pregnancy in just a few taps.
Release: NIH announces winners of data challenge to identify risk factors for first-time pregnancies
Awarded projects seek to reduce pregnancy complications and prevent maternal deaths.
Item of Interest: Una Grewal Appointed Director of the Division of Population Health Research
Dr. Grewal has been acting director of the division since February 2020.
Media Advisory: NIH to study long-term effects of COVID-19 in pregnancy
The National Institutes of Health will support a four-year follow-up study on the potential long-term effects of COVID-19 on women infected with SARS-CoV-2 during pregnancy. The study will also follow their offspring for any potential long-term effects.
Director's Corner: Reflecting on Our Commitment to Nutrition Research
As we usher in November and Thanksgiving, it’s a fitting time to reflect on NICHD’s commitment to research on nutrition.