Read about NICHD’s research findings and activities from 2020.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Release: NIH study suggests using cannabis while trying to conceive may reduce pregnancy chances
Women who use marijuana could have a more difficult time conceiving a child than women who do not use marijuana, suggests a study by researchers at the National Institutes of Health.
Science Update: COVID-19 in third trimester may reduce level of SARS-CoV-2 antibodies transferred across the placenta
For pregnant women with COVID-19 in the third trimester, antibodies against the SARS-CoV-2 virus appear to be transferred to the fetus at lower levels, compared to antibodies against two other respiratory diseases, suggests a study funded by the National Institutes of Health. However, one type of antibody against SARS-CoV-2 was transferred to the fetus more efficiently than the other antibodies against the virus, raising the possibility of at least some immune protection against the disease for the newborn.
Release: Pregnant women in third trimester unlikely to pass SARS-CoV-2 infection to newborns
Pregnant women who are infected with SARS-CoV-2, the virus that causes COVID-19, during the third trimester are unlikely to pass the infection to their newborns, suggests an NIH-funded study.
Science Update: Vegetarian diets during pregnancy associated with small infant birth weight
Vegetarian diets during pregnancy are associated with small infant birth weight, but not a higher risk preterm birth or other medical complications, suggests a National Institutes of Health study.
Science Update: Women with asthma may be at higher risk for weight gain during pregnancy, NIH study suggests
Women with asthma are more likely than normal to gain weight during pregnancy and to retain weight 3 months after giving birth, suggests a National Institutes of Health study. On average, women with asthma gained 3.1 kg (just under 7 lbs) more after a full-term pregnancy than women without asthma. Among women with asthma, weight gain was greater with obesity. Weight gain was also greater with more severe asthma and with asthma triggered by exercise. The study authors suggest that their findings underscore the importance of pre-pregnancy counseling for women with asthma on the need to achieve and maintain a healthy body weight.
Release: Postpartum depression may persist three years after giving birth
National Institutes of Health study suggests women with mood disorders, gestatational diabetes may have a higher risk.
Media Advisory: Plant compound reduces cognitive deficits in mouse model of Down syndrome
The plant compound apigenin improved the cognitive and memory deficits usually seen in a mouse model of Down syndrome, according to a study by researchers at the National Institutes of Health and other institutions. Apigenin is found in chamomile flowers, parsley, celery, peppermint and citrus fruits. The findings raise the possibility that a treatment to lessen the cognitive deficits seen in Down syndrome could one day be offered to pregnant women whose fetuses have been diagnosed with Down syndrome through prenatal testing.
Science Update: Placental DNA in maternal blood could predict later pregnancy complications, NICHD funded study finds
Traces of genetic material from the placenta and other organs circulating in a pregnant woman’s blood stream could potentially be used to predict the risk for complications in later pregnancy, according to a new NICHD-supported study.
Science Update: DNA sequencing technique helpful for identifying genetic causes of fetal fluid buildup, NIH-funded study suggests
Researchers funded by the National Institutes of Health have used a rapid DNA sequencing technique to identify gene variants in roughly a third of cases of nonimmune Hydrops fetalis (NIHF), a serious condition in which a fetus develops fluid buildup inside the abdominal cavity, lungs, or other parts of the body. The findings suggest that the DNA sequencing technique, known as exome sequencing, could be used to provide information unavailable with current genetic testing methods.
Media Advisory: NIH-supported study to track prevalence and impact of SARS-CoV-2 among pregnant women in low- and middle-income countries
The study of approximately 16,000 pregnant women will continue 12 months after childbirth and compare maternal, fetal and newborn outcomes of participants infected with the virus to those of pregnant women who have not.
Release: NIH study suggests opioid use linked to pregnancy loss, lower chance of conception
Opioid use among women trying to conceive may be associated with a lower chance of pregnancy, suggests a National Institutes of Health study. Moreover, opioid use in early pregnancy may be associated with a greater chance of pregnancy loss.
Media Advisory: New tool compares rates of severe pregnancy complications across U.S. hospitals
Scoring system developed by NIH-funded researchers standardizes patient data to aid research, surveillance and improvement initiatives.
Media Advisory: Placenta lacks major molecules used by SARS-CoV-2 virus to cause infection
The placental membranes that contain the fetus and amniotic fluid lack the messenger RNA (mRNA) molecule required to manufacture the ACE2 receptor, the main cell surface receptor used by the SARS-CoV-2 virus to cause infection, according to a study by researchers at the National Institutes of Health.
Item of Interest: NICHD fetal growth calculators available to healthcare providers
New tools estimate fetal growth percentiles and velocity, and they account for racial and ethnic variations.
Science Update: Mouse study links embryo culture after IVF with reduced placental, fetal growth
A mouse study funded by the National Institutes of Health suggests that a step in the in vitro fertilization (IVF) procedure could account for the higher rate of complications in pregnancies resulting from this form of assisted reproductive technology (ART). The researchers linked the culture of embryos in laboratory dishes after fertilization with impaired growth of the placenta, smaller fetal size, and a higher risk of preeclampsia, a serious pregnancy-related blood pressure disorder.
Science Update: Pregnancy, birth complications higher among deaf and hard of hearing women, suggests NIH-funded study
Compared to other women, deaf and hard of hearing women have a higher risk for pregnancy and birth complications such as gestational diabetes and blood pressure disorders, according to a study funded by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development. Moreover, infants of deaf and hard of hearing women were more likely to be born preterm, have low birth weight, and receive a low Apgar score—a screening test used to determine the baby’s need for additional medical services.
Item of Interest: Biospecimens from National Children’s Study pilot now available
Environmental, biological samples span the period from preconception to early childhood.
Release: NIH to test one-dose antibiotic for the prevention of maternal and infant sepsis
Researchers supported by the National Institutes of Health and the Bill & Melinda Gates Foundation will assess whether a single oral dose of the antibiotic azithromycin during labor reduces the risk of maternal and infant bacterial infection and death in seven low- and middle-income countries.
Media Advisory: NIH-funded study to investigate pregnancy outcomes resulting from the COVID-19 pandemic
Researchers to evaluate medical records of 21,000 pregnant women