The NICHD’s Division of Intramural Population Health Research (DIPHR) provides research updates in its newly released annual report for 2014.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Q&A with Human Placenta Project Coordinator David Weinberg
In 2014, NICHD launched the Human Placenta Project (HPP), a new initiative to revolutionize our understanding of the human placenta and its role in health and disease.
NIH announces $41.5 million in funding for the Human Placenta Project
The National Institutes of Health has dedicated $41.5 million for an initiative to understand and monitor the development of the human placenta during pregnancy. The funding will support the development of new technologies to assess the health of the placenta as it grows and matures, with the ultimate goal of improving the health of mothers and children.
Stillbirth may increase women’s long term risk for depression
Women who deliver a stillbirth—but who have no history of depression—may be at a higher risk for long-lasting depression, conclude researchers funded by the National Institutes of Health (NIH). The depression may last beyond the six months most people require to recover from a major loss and persist for as long as 36 months.
Study Reaffirms Safety of Anti-HIV Drugs During Pregnancy
The antiretroviral drugs used to keep HIV at bay are an unqualified success at preventing the spread of the virus from mother to child. The drugs are not only essential for maintaining the health of a pregnant woman with HIV, they have also nearly eliminated the transmission of HIV to her baby. Among U.S. women, the likelihood of a mother passing the virus on to her child is now less than 1%.
NICHD Hosts Upcoming Lecture on Fetal Individualized Medicine
The next NICHD Director’s Lecture at the NIH will feature Diana Bianchi, M.D., from Tufts University School of Medicine. Her talk, titled “Changing Paradigms: From Prenatal Genetic Diagnosis to Fetal Individualized Medicine,” will take place on January 21, 2015, 9:00–10:00 a.m., in Lipsett Amphitheater, at NIH’s Clinical Center in Bethesda, Md.
NIH-sponsored study identifies superior drug regimen for preventing mother-to-child HIV transmission
For HIV-infected women in good immune health, taking a three-drug regimen during pregnancy prevents mother-to-child HIV transmission more effectively than taking one drug during pregnancy, another during labor and two more after giving birth, an international clinical trial has found.
Inflammation in womb affects brain, behavior of baby mice
When researchers triggered an immune response in the wombs of pregnant mice, their offspring showed signs of brain damage that lasted well into adulthood. The animal’s hippocampus—that’s the part of the brain responsible for memory and spatial orientation—was smaller, and they had poor motor skills and behavioral issues, like hyperactivity.
Pregnancy Lifestyle Influences Gestational Diabetes Risk
Nearly half of all cases of diabetes during pregnancy could be prevented if the expecting mothers ate well, exercised regularly, stopped smoking, and maintained a healthy body weight before pregnancy, a new study finds.
October is SIDS Awareness Month
While the prevalence of sudden infant death syndrome (SIDS) in the United States has decreased by 50% over the last 20 years, SIDS remains the leading cause of death for U.S. infants 1 month to 1 year of age.1 This SIDS Awareness Month, the NICHD highlights SIDS resources and research to help parents, caregivers, and medical professionals reduce the risk of SIDS.
Study casts doubt on plans to scale up preterm birth treatment in low resource settings
A study by a National Institutes of Health research network calls into question plans to increase access to steroid treatment for pregnant women in low resource settings at high risk for preterm birth. The study concluded that the treatment—a standard, life-saving practice in high income countries such as the United States—could potentially cause harm in low resource settings where many births take place outside the advance care hospitals that are standard in high income countries.
Integrated approach helps obese women limit weight gain during pregnancy
It’s normal for most women to gain weight during pregnancy, but gaining too much weight can pose serious health risks for mother and baby. Now researchers funded in part by the National Institutes of Health have found that an integrated program offering support and nutrition counseling succeeds where the traditional approaches failed and helps keep women from adding too much weight during pregnancy.
Success rate for vaginal delivery high even after prolonged labor
NIH researchers have concluded that women who experience prolonged labor have an excellent chance for a successful vaginal delivery. However, the researchers did find a slightly increased risk of complications for mothers and babies. The researchers advised women and their health care practitioners to weigh the increased benefits of vaginal delivery against the slightly increased risk.
August Wrap-Up: Promoting Safe and Healthy Pregnancies
This August, we focused on pregnancy—providing information, tips, and resources, plus a chance for members of the public to chat with experts over a Twitter #pregnancychat.
An Aspirin a Day for Preeclampsia Prevention
Aspirin is generally not recommended during pregnancy, as it can lead to bleeding problems for both mother and baby. But for some women, the benefits of a daily low-dose aspirin after the first trimester may outweigh the risk.
Healthy Pre-Pregnancy Diet and Exercise May Reduce Risk of Gestational Diabetes
A series of studies by an NICHD researcher suggests that women who maintain a healthy diet and exercise before they become pregnant are less likely to develop gestational diabetes mellitus, a type of diabetes that occurs only in pregnant women.
Healthy Pregnancies, Healthy Newborns: Research to Improve Outcomes
Ensuring the health and wellbeing of pregnant women and newborns is central to the NICHD mission. Scientists supported by our Pregnancy and Perinatology Branch (PPB) conduct research related to improving care for pregnant women and newborns, preventing preterm labor and birth and other birth complications, and treating diseases in newborns.
NICHD Podcasts Feature Research on Maternal Smoking
Many people are familiar with the health effects of cigarette smoking and secondhand smoke. Research has also tied smoking during pregnancy to later health and behavior problems in children. This podcast round-up features three interviews with NICHD grantees interested in the connections between maternal smoking and child health.
NIH Institutes Commit $2 Million to Small Businesses to Promote Placental Research
This month the NICHD and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) reissued two funding announcements, inviting grant applications for the development of methods to assess placental development and function. The Institutes intend to commit an estimated total of $2 million to small businesses in 2015 to support this research.
New treatment increases pregnancy rate for women with infertility disorder
The drug letrozole appears to be more effective than the standard drug clomiphene for helping women with polycystic ovary syndrome (PCOS) to achieve pregnancy, according to a large study from a research network supported by the National Institutes of Health.