Pheochromocytomas and paragangliomas are rare types of tumors that are typically found in the abdomen but can occur in any location of the body. An international group of health care professionals developed a consensus statement on how to best manage these tumors when they are caused by variants in the gene succinate dehydrogenase complex subunit D (SDHD).
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Science Update: Gene therapy for rare neurodegenerative disease shows early promise
A research team including NICHD scientists has developed a potential gene therapy for hereditary spastic paraplegia 50, a rare childhood-onset neurodegenerative disorder that leads to developmental delays, cognitive impairment, and eventual paralysis.
Spotlight: Women in Science: Dr. Veronica Gomez-Lobo’s Nontraditional Route to Research
Dr. Veronica Gomez-Lobo, director of Pediatric and Adolescent Gynecology at NICHD, began
her career as a clinician focused on caring for underserved populations. Taking advantage of interesting opportunities
led her to become involved in medical education, and later, in scientific research.
Science Update: Cells from umbilical blood vessel lining secrete tiny structures conveying biochemical messages, NIH study suggests
Cells lining the umbilical vein secrete a newly discovered extracellular vesicle—a tiny, balloon-like structure that influences other cells—suggests a study by researchers at the National Institutes of Health. The findings may have implications for understanding fetal development and may inform strategies to use extracellular vesicles to deliver drugs and other therapies.
Science Update: NIH researchers identify new genetic cause for overgrowth disorders
Researchers at NIH have discovered that mutations in the gene SPIN4 cause a rare overgrowth disorder in people.
Science Update: Biomarker for Niemann-Pick type C may be useful for diagnosing other class of rare disorders, NIH study suggests
A biomarker used to detect a rare neurodegenerative disorder of cholesterol metabolism, Niemann-Pick disease type C1 (NPC1), may also be useful for diagnosing another class of rare diseases known as congenital disorders of glycosylation (CDG), suggests a study by researchers at the National Institutes of Health.
Spotlight: Scientific Advances from the Division of Intramural Research
The Division of Intramural Research provides fundamental knowledge about the nature and behavior of living systems through basic, clinical, and population-based research.
Item of Interest: NICHD Scientific Director Christopher McBain Elected AAAS Fellow
Christopher McBain, Ph.D., scientific director of the Division of Intramural Research at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), has been elected as a fellow of the American Association for the Advancement of Science (AAAS).
Release: Neuroscientist McBain appointed director of intramural research at NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development
Christopher McBain, Ph.D., has been appointed scientific director and director of the Division of Intramural Research at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health.
Director's Corner: Reflecting on NICHD’s 60th Anniversary Year
Research conducted at NICHD and at NICHD-funded institutions continues to bring us closer to fulfilling our vision of ensuring healthy pregnancies, healthy children, and healthy and optimal lives.
Science Update: NIH researchers map cellular activity underlying infection-induced preterm labor
Mouse study improves understanding of events leading to preterm labor and birth
Selected NICHD Research Advances of 2022
Read about NICHD’s research findings and activities from 2022.
Science Update: Mouse model of rare disease highlights importance of balance between two opposing proteins
Reducing levels of the protein WAPL may partially correct disease traits caused by a deficiency of NIPBL, a protein with the opposite function, suggests a mouse study by NICHD scientists. The findings suggest the importance of striking a proper balance between NIPBL and WAPL activities and improve understanding of the mechanisms underlying the rare developmental disorder Cornelia de Lange syndrome.
Director's Corner: Expanding Contraceptive Choices
A safe, highly effective, reversible method of male contraception would fill an important public health need. Additionally, multipurpose prevention technologies (MPTs)—products that prevent both pregnancy and sexually transmitted infections—would increase sexual and reproductive health options for both women and men. NICHD supports a broad range of contraceptive research, including efforts to develop male contraceptives and MPTs.
Science Update: Caffeine consumption during pregnancy may lead to slightly shorter child height
Exposure to caffeine in the womb, even in small amounts, may lead to shorter height in childhood, suggests an analysis by NICHD researchers. Children of women with low caffeine intake during pregnancy were slightly shorter than their peers born to women who consumed no caffeine while pregnant. The gaps in height widened between ages 4 and 8 years.
Spotlight: Scientific Advances from the Division of Intramural Research
The Division of Intramural Research provides fundamental knowledge about the nature and behavior of living systems through basic, clinical, and population-based research.
Science Update: NIH-led working group proposes new paradigm of ovarian anatomy
A group of experts led by NICHD has proposed a new anatomic model of the ovary and recommended standardized nomenclature to describe its major features.
Spotlight: Expanding Research Opportunities at NIH for Howard University Students
Learn about a collaboration between NICHD and Howard University.
Item of Interest: NICHD researchers collaborate with basic scientists to understand rare, fatal childhood neurological disorder
NICHD researchers conducting a clinical study of patients with a rare, fatal neurological disorder have partnered with basic scientists to find better ways to understand the disease, monitor its progression, and ultimately find treatments.
Spotlight: Advancing neuroscience research for children around the world
Eight years ago, NIH announced a collaboration with the Bill & Melinda Gates Foundation to develop solutions for a variety of global health challenges. Learn how NICHD research is supporting this goal.