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Gene linked to excess male hormones in female infertility disorder
A variant in a gene active in cells of the ovary may lead to the overproduction of androgens—male hormones similar to testosterone— occurring in women with polycystic ovary syndrome (PCOS), according to scientists funded by the National Institutes of Health. The discovery may provide information to develop a test to diagnose women at risk for PCOS and also for the development of a treatment for the condition.


NICHD podcast features research on adrenal gland disorders
This month’s NICHD Research Perspectives podcast focuses on adrenal gland disorders and research conducted by NICHD staff at the NIH Clinical Center.


Scientific Vision: The Next Decade
The NICHD embarked upon a collaborative process in 2011 to create a scientific Vision, identifying the most promising scientific opportunities for the Institute and its partners to pursue over the next decade. The newly published Scientific Vision statement presents the results of that process and outlines scientific goals for the coming decade.


NICHD reorganizes extramural program
​Alan Guttmacher, M.D., Director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) announced a number of changes to streamline the institute’s organizational structure and accelerate the exchange of scientific ideas.


NICHD vision statement now available online
A document charting a research course for the many collaborators who share an interest in promoting the science concerning human development through the life span, child health, women's health, and rehabilitation research is now available online.


Research for a Lifetime: Commemorating the NICHD’s 50th Anniversary
On October 17, 1962, President John F. Kennedy signed into law the legislation establishing the NICHD to examine “the complex process of human development from conception to old age.” The Institute marks its golden anniversary with Research for a Lifetime, an all-day scientific colloquium to highlight the Institute’s mission, accomplishments, and future research directions.


Evidence-based Methodology Workshop on Polycystic Ovary Syndrome (PCOS)
​PCOS is a leading cause of infertility in women and is linked to a variety of health problems. The NICHD and the NIH Office of Disease Prevention are convening a workshop to evaluate the best evidence currently available on PCOS diagnosis criteria, causes, long-term health consequences, and management and prevention.


June NICHD Director's Podcast Now Online
The June 2012 NICHD Research Perspectives—NICHD' monthly podcast series—features discussions of a treatment that reduces the body temperatures of infants who experience oxygen deficiency at birth, the effectiveness of progesterone as a treatment for the infertility associated with polycystic ovary syndrome, and the influence that engaging the attention of young children with autism has on their language development.


Focus on Infertility Research at the NICHD
Infertility is a broad term used to define any condition that prevents a man or woman from conceiving a child or that interferes with carrying a pregnancy to term. In this Spotlight, the NICHD describes some of its research activities and recent findings related to infertility causes and treatments for both men and women.


Progestin Treatment for Polycystic Ovarian Syndrome may Reduce Pregnancy Chances
The hormone progestin, often given as a first step in infertility treatment for polycystic ovary syndrome (PCOS), appears to decrease the odds of conception and of giving birth, according to a study by a National Institutes of Health research network.


NIH Obesity Research Featured in HBO's The Weight of the Nation
Obesity is one of today's most pressing health issues facing this country. On May 14 and 15, 2012, HBO premieres The Weight of the Nation, a four-part documentary exploring the personal costs of and scientific advances related to obesity. The series reflects years of research supported by the NIH, including the NICHD, that has helped shape our understanding of obesity, as well as ways to prevent and treat it at every stage of life.


Women Sought for NIH Study of Infertility Disorder
Young women in the Washington, D.C., area who have polycystic ovarian syndrome (PCOS) are encouraged to take part in a study at the National Institutes of Health on the possible role of the adrenal glands in the disorder.


Recovery Act Funds Key Reproductive Health Research
Millions of Americans with reproductive health disorders stand to benefit from new research funded by the National Institutes of Health. With funds from the American Recovery and Reinvestment Act, the National Institutes of Health today announced grants totaling nearly $60 million for research into disorders that impair fertility, cut short a woman's reproductive years, and often cause intense pain.


Gene Variation Predicts Response to Treatment in Common Infertility Disorder
NIH-sponsored researchers have discovered that women who have polycystic ovary syndrome (PCOS) are less likely to ovulate in response to a promising new drug treatment for the condition if they have a variation in a particular gene.


Standard Therapy More Effective Than Diabetes Drug for Achieving Pregnancy in Common Fertility Disorder
Metformin, a drug used to treat diabetes and thought to hold great promise at overcoming the infertility associated with polycystic ovary syndrome (PCOS), is less useful for helping women with the condition achieve pregnancy than is the standard treatment with the infertility drug clomiphene, report researchers in an NIH research network.


Oral Diabetes Drug Shows Promise in Preventing Miscarriage in Common Infertility Disorder
The anti-diabetes drug metformin appears to reduce the likelihood of early miscarriage in women with a common form of female infertility, according to a study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).


For details and further information on select NICHD News Releases, please see Backgrounders.

Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology