High-Risk Pregnancy: NICHD Research Goals

Research on high-risk pregnancy focuses on maternal physiology, environmental variables, and conditions and treatments occurring during pregnancy that affect the health of the mother and fetus. Topics of interest include:

  • Pathophysiological states of pregnancy
  • Prevention of stillbirth and preterm birth
  • The health impact on mother and infant of pregnancy-related disorders
  • Understanding the effects of pregnancy on women with chronic medical conditions and disabilities
  • Pathogenesis of maternal infections and their effects on fetal development
  • The effect of maternal medications and a mother’s use and abuse of drugs on fetal development
  • Adolescent pregnancy

Understanding pregnancy processes and fetal development can pave the way for predicting and preventing poor pregnancy outcomes for mothers and their newborns in the United States and around the world.

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