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Can epigenetic changes & developmental epigenetic changes cause cancer?

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Epigenetic changes can be associated with many types of cancer. Cancer was the first human disease to be linked to epigenetics.1

It is unlikely that epigenetic changes alone cause any one cancer. Rather, most cancers are caused by the build-up over time of many different mutations and epigenetic changes in many different genes.

  1. Simmons, D. (2008). Epigenetic influences and disease. Nature Education, 1(1). Retrieved July 24, 2012, from External Web Site Policy [top]

Last Reviewed: 10/28/2013
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology