Concepts for proposed Requests for Applications (RFA) are reviewed during the Open Session of Council. These are the features of the process:
This approach to concept review:
For this meeting, two concepts were reviewed:
Intellectual and Developmental Disabilities Research Centers Learning Disabilities Research Centers
A Request for Applications is proposed entitled “Intellectual and Developmental Disabilities Research Centers (IDDRC) 2010.” The proposed RFA will use the Centers award (P30) mechanism.
This RFA is a continuation of one of NICHD’s cornerstone programs, the Intellectual and Developmental Disabilities Research Centers (IDDRCs), which eligibility is open to qualifying institutions. The original IDDRCs were established by Congressional mandate in the early 1960s to provide facilities and support for research in intellectual and developmental disabilities (IDD, formerly mental retardation), and develop university-affiliated facilities to train personnel to provide care for individuals with IDD. There are currently 14 funded IDDRCs located at universities and children’s hospitals throughout the country, with a focus on providing core equipment, services, and personnel to support investigators whose goal is to understand the causes of and develop treatments for IDD. Over the past 40 years, the Centers’ activities have increased this understanding dramatically, and the core services have expanded to include state-of-the-art infrastructure support in such fields as developmental neurobiology, genomics, proteomics, neuroimaging, epidemiology, biostatistics, behavioral science and clinical translational research. Since its original inception, the IDDRC program has continued to evolve and mature, with the Centers promoting collaborative, interdisciplinary projects within and between Centers and serving as focal points for IDD research and training throughout the US.
The proposed RFA will solicit applications to establish or continue an Intellectual and Developmental Disabilities Research Center that provides shared cores, resources, and facilities to promote multidisciplinary research in the field of IDD. Although the goal of the IDDRCs is provide research support to multiple investigators rather than directly fund research projects, the breadth and depth of the supported research projects is immense; in fact, many of these projects have as their funding sources other NIH Institutes such as NINDS and NIMH, and a number are supported by foundations and private research institutions. The IDDRCs have demonstrated a remarkable ability to leverage resources from their host institutions, private donors, and other sources to facilitate growth. This diversity allows the Centers to support substantially more projects and affiliates than would be possible using NICHD support alone.
The objective of this RFA is to fund Centers that will provide support and facilities for a cohesive, interdisciplinary program of research and research training in intellectual disabilities and related aspects of human development. Applicants are encouraged to develop translational and collaborative research programs that will provide infrastructure for investigators who will make substantive advances in the field of IDD.
Melissa A. Parisi, M.D., Ph.D.
Intellectual and Developmental Disabilities Branch
Center for Developmental Biology and Perinatal Medicine
A Request for Applications (RFA) is proposed entitled “Learning Disabilities Research Centers.” This proposed RFA will use the specialized research center grant (P50) mechanism.
The purpose of this recurring RFA is to continue to stimulate transdisciplinary research examining issues related to etiology, classification and definition of, and prevention and remediation of learning disabilities impacting listening, speaking, reading, writing and mathematics with an emphasis on comorbid conditions. The P50 mechanism allows for richly integrative, multi-method approaches to examining research topics focusing on learning disabilities that are simply not feasible through standard research mechanisms.
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) maintains a longstanding interest in the study of normal language and reading development, learning disabilities, and disorders that adversely affect the development of listening, speaking, reading, writing, and mathematics abilities. Continuation of the Learning Disabilities Research Centers program provides a unique opportunity to continue the strong transdisciplinary research connecting behavioral, neurobiological and genetic studies of reading, writing and related learning disabilities which is difficult to facilitate through other mechanisms.
The continuation of the Learning Disabilities Research Centers would refine the classification and definition models for learning disabilities, further extend basic and translational research on learning disabilities in the area of reading and writing skill development across the lifecourse, continue dissemination of translational research to researcher and practitioners, and increase the research data directly relevant to highly diverse populations.
Program Contact:Brett Miller, Ph.D.Child Development and Behavior BranchCenter for Research for Mothers and Children