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Dever, Tom

Formal Title:

Senior Investigator





6 CENTER DR Room 228, MSC 0609
Bethesda Md 20892-0609
For FedEx use:
Bethesda Md 20892

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Dr. Thomas Dever is head of the Section on Protein Biosynthesis in the Laboratory of Gene Regulation and Development of the NICHD at the NIH, a position he has held since 1994. The Dever lab studies the mechanism of regulation of eukaryotic protein synthesis. Using a combination of yeast molecular genetic, biochemical and structural techniques they are gaining new insights into the process of cellular protein synthesis and dissecting the structure-function properties of the cellular factors that promote translation. They are also studying viral regulators of the eIF2 kinases in an effort to understand at the molecular level how these kinases regulate protein synthesis and how their activities can be modulated in response to environmental or developmental cues.

Dr. Dever received his B.S. in Chemistry from Gannon University, Erie, Pennsylvania in 1984. He received his Ph.D. in Biochemistry in 1990 from Case Western Reserve University in Cleveland, Ohio where he initiated his studies on eukaryotic translation in the laboratory of Bill Merrick. He studied as a post-doctoral fellow in the laboratory of Alan Hinnebusch in the NICHD from 1990 to 1994. In addition to his research activities Dr. Dever serves on the editorial board of the journal Molecular Cell.

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