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Eisenberg, Esther

Formal Title:



Program Director, Reproductive Medicine and Infertility Program; Project Scientist of the NICHD Reproductive Medicine Network; planning and execution of reproductive medicine/infertility portfolio; review of oversight and monitoring of clinical trials; analysis of clinical data; preparation of protocol summaries and progress reports; manuscript preparation and publication; long-range planning of reproductive medicine programs; interact with physician scientists; review progress reports





6710B ROCKLEDGE DRIVE Room 2359A, MSC 7002
Bethesda ,MD 20817


I received my medical training at Albert Einstein College of Medicine in New York, residency training in Obstetrics and Gynecology at Tufts University Medical Center in Boston, and completed a fellowship in Reproductive Endocrinology and Infertility at Pennsylvania Hospital of the University of Pennsylvania in Philadelphia. I was an Assistant Professor of Obstetrics and Gynecology at University of Pennsylvania (Pennsylvania Hospital), where I started and directed one of the first in vitro fertilization (IVF) programs in the United States from 1983 until 1992. Since then, I have been a reproductive endocrinologist and Professor of Obstetrics and Gynecology and Director of the Division of Reproductive Endocrinology and Infertility at Vanderbilt University Medical Center in Nashville, Tennessee. After joining the faculty of Vanderbilt University School of Medicine in 1992, I completed a Master’s of Public Health with an emphasis in epidemiology at Vanderbilt University in 2000. Since 2007, I have also served as Medical Officer in the Fertility and Infertility Branch and the Project Scientist of the Reproductive Medicine Network, a cooperative multicenter clinical trials network that studies infertility and reproductive diseases and disorders.  



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My overarching goal is to improve women’s health.  I have tried to accomplish this through various avenues including clinical care of women with reproductive diseases and disorders, teaching medical students and residents, working collaboratively to do research on endometriosis and infertility, and through advancing knowledge both in peer reviewed journals and also in writings directed at the general public and health care consumer.  I have written numerous articles on endometriosis, infertility and hormonal problems in women, and co-authored a book, Hysterectomy: Exploring Your Options, published by the Johns Hopkins Press in 2003.  Currently, I serve on the Editorial Board of Fertility and Sterility.  My areas of expertise are hormonal problems in women including infertility, ovulation induction, menstrual diseases and disorders, polycystic ovarian syndrome, endometriosis, and menopause and its consequences.  

Publications (PubMed):

Long-term outcomes in children born after assisted conception.
Endometrial shedding effect on conception and live birth in women with polycystic ovary syndrome.
Predictors of pregnancy and live birth after insemination in couples with unexplained or male-factor infertility.
The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome.
Recruitment challenges of a multicenter randomized controlled varicocelectomy trial.
Proactively establishing a biologic specimens repository for large clinical trials: an idea whose time has come.
Establishing a biologic specimens repository for reproductive clinical trials: technical aspects.
Estimating rates of multiple gestation pregnancies: sample size calculation from the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial.
Increasing burden of institutional review in multicenter clinical trials of infertility: the Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies.
Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism.
Decision trees for identifying predictors of treatment effectiveness in clinical trials and its application to ovulation in a study of women with polycystic ovary syndrome.
Reduced expression of progesterone receptor-B in the endometrium of women with endometriosis and in cocultures of endometrial cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Endometrial biology and the etiology of endometriosis.
Reduced progesterone action during endometrial maturation: a potential risk factor for the development of endometriosis.
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