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Kennison Lab: Section on Drosophila Gene Regulation

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Jim Kennison, who heads the Section on Drosophila Gene Regulation, studies the genomics of pattern differentiation in Drosophila. The group defined cis-acting regulatory sequences in the Sex combs reduced gene, indicating that, after the end of embryogenesis, two genetic elements about 70 kb apart in the Sex combs reduced gene must be in cistrans-acting factors that maintain proper repression of the homeotic genes have been identified in screens for new recessive mutants in somatic clones. While characterizing the essential genes within two regions that span about 1% of the Drosophila genome, the group also identified the first gene desert in Drosophila, a region of 55kb with many evolutionarily conserved DNA sequences, but with no apparent function under laboratory conditions. ​​

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Last Reviewed: 11/30/2012

Contact Information

Name: Dr Jim Kennison
Senior Investigator
Section on Drosophila Gene Regulation
Phone: 301-496-8399
Fax: 301-496-0243

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Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology