Skip Navigation
  Print Page

Ahn Lab: Unit on Developmental Neurogenetics

Skip sharing on social media links
Share this:
Skip Internal Navigation ​​​​

Overview

Sohyun Ahn, who heads the Unit on Developmental Neurogenetics, and colleagues continue to investigate the role of Sonic hedgehog (Shh) signaling and its downstream effectors in neurogenesis of the developing and mature brain. Using conditional gene ablation approaches in the mouse, the Unit demonstrated a requirement of Gli3, a major negative regulator of Shh pathway, in neural progenitors in developing neocortex and in establishment of the postnatal neurogenic niche in the subventricular zone of the lateral ventricle. The Unit is currently characterizing additional signaling cues provided by the neurogenic niche that control the behavior of neural stem cells. Another project revealed that spatial and temporal genetic lineages of dopamine neuron precursors determine diversity among dopamine neurons.

​​​​​​​​​​​​​​ ​​​​​​​​​
Last Updated Date: 11/30/2012
Last Reviewed Date: 11/30/2012

Contact Information

Name: Dr Sohyun Ahn
Investigator
Section on Vertebrate Organogenesis
Phone: 301-402-2426
Fax: 301-402-0543
Email: ahnsohyun@mail.nih.gov

Staff Directory
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology