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Mayer Lab: Section on Neurophysiology and Biophysics

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Mark Mayer's Section on Neurophysiology and Biophysics, investigates ionotropic glutamate receptors (iGluRs)—the molecular pores that mediate signal transmission at the majority of excitatory synapses in the mammalian central nervous system. Given the receptors' essential role in normal brain function and development as well as mounting evidence that dysfunction of GluR activity mediates several central nervous system diseases and damage during stroke, the Section studies receptor mechanisms by combining atomic-resolution structural data obtained by X-ray diffraction with functional data collected from rapid perfusion techniques and patch clamp recording.

Last Reviewed: 04/09/2015

Contact Information

Name: Dr Mark L Mayer
Senior Investigator
Section on Neurophysiology and Biophysics
Phone: 301-496-9346
Fax: 301-496-2396

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