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Serpe Lab: Unit on Cellular Communication

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Overview

The Unit on Cellular Communication, headed by Mihaela Serpe, investigates molecular mechanisms that regulate cellular signaling during development, employng the Drosophila system. The group's studies on early embryonic patterning showed how evolutionary changes in proteolytic destruction of the BMP-binding protein Sog by Tolloid/BMP-1 have influenced morphogen gradient formation and function in the Drosophila embryo. The group recently identified a neuropillin and tolloid-like protein, Neto, as a component essential for clustering the ionotropic glutamate receptors at the Drosophila neuromuscular junction.

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Last Updated Date: 04/22/2014
Last Reviewed Date: 04/22/2014

Contact Information

Name: Dr Mihaela Serpe
Investigator
Unit on Cellular Communication
Phone: 301-435-1940
Fax: 301-402-1323
Email: serpemih@mail.nih.gov

Staff Directory
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology