Skip Navigation
Print Page

Program in Cellular Regulation and Metabolism (PCRM)

Skip sharing on social media links
Share this:

Alan Hinnebursch, Program Director

The seven investigators in this program, all belonging to the Laboratory of Gene Regulation and Development (LGRD), apply a combination of genetics, biochemistry, cell biology, and structural biology to elucidate the molecular basis of processes fundamentally important in cell biology or animal development. Three of the seven groups study molecular mechanisms of transcriptional and translational control of gene expression and the transposition of retroelements in budding or fission yeast. Two groups employ the fruit fly Drosophila to investigate molecular mechanisms in development, including the molecular basis of neuronal connection specificity in the visual system, receptor clustering at synapses of the neuromuscular junction, and cell signaling by TGF-beta factors. The aneuran Xenopus laevis serves as a model system for the work of the remaining two groups, one of which focuses on spindle assembly and chromosome segregation and the other on transcriptional programming of adult stem cells in organ development during metamorphosis.

​​​​​​​ ​​​​​​​​
Last Reviewed: 11/30/2012

Contact Information

Name: Dr Alan G Hinnebusch
Senior Investigator
Program in Cellular Regulation and Metabolism
Phone: 301-496-4480
Fax: 301-496-6828

Staff Directory
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology