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Epidemiology Branch (EB)

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EB Research - Reproductive Epidemiology

Air Quality and Reproductive Health - Longitudinal Investigation of Fertility and the Environment (LIFE) Study

Air pollution exposure has been associated with decrements in semen quality including DNA damage and recent animal research suggests there may be an effect on fertility measures in females as well. We use the Community-Multiscale Air Model (CMAQ) to determine exposure for criteria air pollutants including PM2.5 and ozone as well as over 30 air toxics, temperature and relative humidity to examine reproductive health effects in the LIFE Study. Couples attempting pregnancy at study sites in Michigan and Texas (n=501) have residential air pollution exposure assigned by CMAQ as well as using other air pollution modeling strategies based on monitor data and proximity to major roadways. Exposure models will be completed in 2013.

Principal Investigator

Pauline Mendola, Ph.D.

DIPHR Collaborators

Last Reviewed: 09/09/2014

Contact Information

Name: Dr Enrique Fabian Schisterman
Chief and Senior Investigator
Epidemiology Branch
Phone: 301-435-6893
Fax: 301-402-2084

Staff Directory
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology