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Pediatric Critical Care Research and Training Program

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Through this program, the PTCIB supports research and training opportunities to inform the practice of health care providers who stabilize, diagnose, and manage the care of critically ill children of all ages. Such research focuses on investigating the safety and effectiveness of treatment and management strategies for all sorts of pediatric critical illness and injury, including sepsis (blood infection), multiple organ dysfunction syndrome, acute lung injury, and traumatic brain injury (TBI). In addition, we will support research focused on the care of critically ill children with complex chronic health problems and on the toll that such illness takes on the family.

Within the Pediatric Critical Care Research and Training Program, there are two complementary research portfolios, described below.

Pediatric Critical Care Medicine, Pathophysiology, and Management of Critical Illness Portfolio

This portfolio—managed by Robert Tamburro—includes projects on:

  • Physiology/Pathophysiology of critical illness
  • Biomarkers related to critical illness
  • Medical and pharmacological management of critical illness
  • Pediatric surgery and surgical intervention
  • Anesthesia
  • Remote monitoring/Telemedicine
  • Statistical modeling studies of critical illness
  • Medical devices
  • Conditions of particular interest:
    • Multiple organ dysfunction
    • Sepsis
    • Acute, severe traumatic brain injury
    • Serious life-threatening injury
    • Acute lung injury
    • Critical illness in children with complex, chronic conditions

Ethical, Translational, and Applied Research in Pediatric Critical Care Practice Portfolio

This portfolio—managed by Tammara Jenkins—includes projects on:

  • Nursing and non-pharmacological management of critical illness
  • Bereavement, palliative care, end-of-life in PICU populations
  • Ethical issues related to critical illness and pediatric critical care research
  • Functional outcomes of critical illness
  • Environment of care
    • Healthcare systems
    • Interdisciplinary healthcare team dynamics and family communication
    • Clinical education and training
    • Patient safety
  • Psychosocial aspects of critical care (child, family, and healthcare provider)
  • Care-based implementation science

In addition to investigator-initiated research, the Pediatric Critical Care Program also supports a number of research training programs, including the Pediatric Critical Care and Trauma Scientist Development Program, a national faculty training and career development program that develops successful pediatric critical care and trauma physician scientists who conduct research to enhance the scientific understanding, clinical management, and rehabilitation of pediatric trauma and critical illness.

The program also supports the Collaborative Pediatric Critical Care Research Network, which serves as a national resource for studying the scientific bases of pediatric critical care medicine.​ ​​

Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology