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Cellular and Molecular Biology, including Biochemical and Metabolic Research

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Because biochemical pathways are fundamental to normal body and brain function, changes in those pathways can disrupt not only the pathway itself, but also the processes and functions that rely on the pathway’s products and byproducts. 

The IDDB funds research on biochemical processes and metabolism as these topics relate to brain functioning, brain injury, and long-term consequences to the brain.  The Branch’s efforts include research in hypoxia/ischemia, mitochondrial disorders, many inborn errors of metabolism, including urea cycle disorders, lysosomal storage disorders, errors of amino acid metabolism (e.g., phenylalanine hydroxylase deficiency or phenylketonuria [PKU]), organic acidemias (e.g., propionic aci demia), and disorders of cholesterol metabolism, among others.​

Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology