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Preimplantation Genetics and Development

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This program, directed by Dr. Ravi (Neelakanta) Ravindranath, supports research related to the genetic and epigenetic control mechanisms that impact upon the quality of oocytes and preimplantation embryos, including mitochondrial function. The relationships between oocytes, preimplantation embryos, and stem cells are a vital part of this program.

The role of epigenetics in reprogramming in early embryos, embryonic stem cells, induced pluripotent stem cells, other stem cells, and in cloning (somatic cell nuclear transfer), as well as the processes of self-renewal and differentiation of gametes, form a major focus of this program. Much of this research also provides critical foundations for the development, implementation, and efficacy and safety testing of assisted reproductive technologies, including preimplantation genetic diagnosis.​​

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