201505 Omics Approaches to Assess Human Placental Development and Function in Real Time

A Request for Applications with set-aside is proposed entitled, “Omics Approaches to Assess Human Placental Development and Function in Real Time” using the R01/R21 Research Project/Exploratory/Developmental grant mechanisms.

Purpose

The purpose of the proposed initiative is to leverage omics approaches to monitor human placental development and function in a safe, non-invasive or minimally-invasive manner in real time across pregnancy. Abnormalities of placental development and function are known to underlie many major pathologies of pregnancy, but there is a paucity of in vivo information obtained at early times in gestation when many of the pregnancy pathologies are believed to have their origins.

Scope

The proposed RFA will solicit applications aimed at the application of omics approaches alone or in combination with other technologies to identify and validate biomarkers of human placental development and/or function throughout gestation. Approaches known to be contraindicated for use in pregnant women will not be allowed.

Objectives

The objective of the RFA is to apply omics in order to assess human placental development and function in real time across pregnancy. This may include the development and application of new tools or technologies as well as the application of current technologies.

Program Contact

David Weinberg, Ph.D.
Office of the Director

 

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