In addition to the specific research efforts described on this Web site, the NICHD also conducts and supports projects on other topics related to pregnancy and birth.

Drug Safety in Pregnant Women

During pregnancy, women may need medical care that requires the use of medications or supplements, either by prescription or over-the-counter. Giving medications to a pregnant woman can affect the health of her fetus. Similarly, there are times when the fetus needs medication for some reason. Giving medication to a fetus in the womb can also have effects on the mother's health.

Despite these needs, very few of the medications and supplements available today have been tested in pregnant women, to determine their safety and effectiveness for both mother and fetus. Without evidence on drug safety in pregnant women, health care providers can't be sure they're making safe recommendations to their patients about medications and supplements.

The Food and Drug Administration (FDA), the government agency with primary responsibility for labeling medications and supplements, has joined the NICHD in searching for a solution to this potentially dangerous situation.

The FDA is working to change existing drug regulations in regard to use in pregnant women. With these changes, drug companies will have to provide evidence that a drug is safe for both mother and fetus before it can receive proper labeling.

For its part, the NICHD has started the Obstetric- Pharmacology Research Unit Network to support new research on the safety and effectiveness of medications used during pregnancy. For more information on this and other pharmacology research efforts, please visit the Obstetric and Pediatric Pharmacology Branch Web site.

Reproductive Health in Women with Disabilities

Through its National Center for Medical Rehabilitation Research (NCMRR), the NICHD is working to understand the issues that women with disabilities face, in terms of their reproductive health. Much of this research occurs within the projects that address the overall health of and health promotion for women with disabilities.

Some of the research projects supported by the NCMRR include: finding body responses to spinal cord injury that are unique to women; understanding how spinal cord injury impacts a woman's sexual responses and sexual health; learning how arthritis and multiple sclerosis affect women's reproductive health; realizing how menopause and the stages of menopause are unique in women with disabilities.

The Center for Research on Women With Disabilities (CROWD), at the Baylor College of Medicine in Texas, conducts research on a wide range of topics in the area of women with disabilities. The NCMRR has provided support for the Center in the past. The CROWD Web site offers patient information on reproductive health for women with disabilities. The site also offers results from the National Study of Women with Physical Disabilities, a study supported by the NCMRR that spurred the creation of CROWD.

In addition, the NICHD recently sponsored a meeting on Pregnancy in Women with Physical Disabilities.