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Appendix B

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Table 2. History and Blood Phe Levels of 67 PKUCS Subjects Enrolled in the Adult Follow-up Study(Values tabulated are mean ± s.d.)

Age (years) Diet Discontinued n Max Dx Phe (mg/dL) Age 1st Tr. (days) 6 years Blood Phe Level (mg/dL) 10 years Blood Phe Level (mg/dL) Current Blood Phe Level (mg/dL)
4.8 - 6.5 years 36 49±12 21±11 13±4 27±6 24±7
4.8 - 6.5 years Never Resumed 22 49±12 23±12 14±4 27±6 27±6
4.8 - 6.5 years Some Additional Treatment 14 49±9 19±10 13±4 26±6 20±7
6.5 - 12.5 years 13 57±15 21±16 12±5 20±6 26±10
6.5 - 12.5 years Never Resumed 7 58±14 28±19 14±5 21±8 26±7
6.5 - 12.5 years Some Additional Treatment 6 57±17 13±5 9±3 19±5 25±13
12.5 - 20.0 years 11 48±9 19±9 12±5 14±5 20±7
12.5 - 20.0 years Never Resumed 5 48±2 19±9 12±5 15±53 23±5
12.5 - 20.0 years Some Additional Treatment 6 48±13 19±9 11±7 14±7 18±8
Never Discontinued 7 41±10 16±13 9±3 11±3 16±6

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Last Updated Date: 08/28/2006
Last Reviewed Date: 08/28/2006
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology