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Spinal Cord Injury (SCI): Overview

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SCI is typically caused by a traumatic blow to (or penetration of) the spine that fractures or dislocates vertebrae. The trauma causes the resulting bone fragments, material in the spinal discs, or ligaments to bruise or tear into spinal cord tissue, damaging it or, in some cases, severing the cord entirely and resulting in partial or complete paralysis. The NICHD supports basic research related to SCI and promotes the development and application of devices, including prosthetics and wheelchairs, and the use of biomechanical modeling to improve the quality of life for people regardless of their injury. 

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Common Name

  • Spinal cord injury (SCI)

Scientific Names

  • Tetraplegia (pronounced te-truh-PLEE-jee-uh and formerly called quadriplegia [pronounced kwod-ruh-PLEE-jee-uh])
  • Paraplegia (pronounced par-uh-PLEE-jee-uh)
Last Updated Date: 07/30/2013
Last Reviewed Date: 05/28/2013
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology