The NICHD conducts and supports a variety of clinical research related to preterm labor and birth. Select a link below to learn more about these projects.
Featured NICHD Clinical Trials on Preterm Labor and Birth
- Surgical Procedures to Prevent Preterm Birth: Pregnant women who have a shortened cervix and have previously had a preterm baby are at increased risk for having another preterm baby. This study will determine whether reinforcing the cervix with a surgical stitch can reduce the chance of a preterm birth.
- Prematurity and Infant Neurological Disorders: Prematurity is a leading risk factor for cerebral palsy. Two-thirds of preterm neonates are born to mothers with preterm labor with intact membranes or preterm premature rupture of membranes. A growing body of evidence suggests that these conditions are heterogeneous. This is an observational cohort study designed to identify the mechanisms of disease in patients with preterm labor/contractions and preterm premature rupture of membranes and to describe the relationship between clinical, biochemical, histological, and biophysical parameters and the development of infant neurological disorders.
- Biological Mechanisms Underlying Preterm Birth: This study aims to investigate the basic mechanisms of preterm labor by systematically cataloging the changes in expression levels of all expressed genes whose sequences are available. The goals will be accomplished by using microarray technology followed by subsequent confirmative or complementary analyses.
NICHD Clinical Trials
ClinicalTrials.gov Search Results
Information on current NIH-sponsored clinical trials on preterm labor and birth is available at the links below or by calling 800-411-1222.