The NICHD conducts and supports a variety of clinical research related to POI. Select a link below to learn more about these projects.
Featured NICHD Clinical Trials on POI
The following NICHD clinical studies are currently recruiting participants:
POI Clinical Research Program
Doctors at the NIH are conducting a clinical research program whose goal is to develop improved treatments for young women with POI. These studies will help doctors and patients learn more about POI. This research also will clarify the ways POI differs from menopause.
Feasibility Study for Development of an Early Test for Ovarian Failure
This study aims to gain information about normal ovarian function that will be useful in developing a test for early detection of ovarian failure.
The Natural History of Reproductive and Overall Health in Girls and Women With a Premutation in the FMR1 Gene: Creation of a Patient Registry
Women with the Fragile X gene premutation are at higher risk for POI and other health problems. The purpose of this research effort is to develop a patient registry of women with an abnormal FMR1 gene and to monitor their general and reproductive health.
Ovarian Follicle Function in Patients With Premature Ovarian Failure No proven therapy to restore ovarian function and fertility is available to patients with POI. This research protocol will look at clinical features of patients to identify who might be suitable for later clinical trials to test therapies to restore ovarian function.
NICHD Clinical Trials
ClinicalTrials.gov Search Results
Information on current NIH-sponsored clinical trials on “Primary Ovarian Insufficiency” is available at the link below or by calling 800-411-1222.