The NICHD conducts and supports a variety of clinical research related to obstetrics. Select a link below to learn more about some of these ongoing projects.
Featured NICHD Clinical Trials
- Oral L-Citrulline and ADMA in Pregnancy
This study's goal is to determine if oral usage of L-citrulline (3 grams/day) for 3 weeks provided in mid-pregnancy to obese subjects will decrease the plasma ADMA/L-aginine ratio, lower maternal blood pressure, improve endothelial-dependent vascular function and peripheral vascular stiffness, and improve uterine artery Doppler resistance and flow.
- Establishment of a Perinatal Database and a Bank of Biological Materials
The aim of this project is to establish a clinical database and a bank of biological materials that will be used to improve the understanding of the mechanisms underlying various pregnancy diseases.
- Fetal ST Segment and T Wave Analysis in Labor (STAN)
The purpose of this research is to test a new instrument called a fetal STAN monitor that may be used during labor to monitor the electrical activity of the fetus's heart.
- Biological Markers of Disease in the Prediction of Preterm Delivery, Preeclampsia, and Intra-Uterine Growth Retardation: A Longitudinal Study
Preterm delivery, preeclampsia, and intrauterine growth restriction are leading causes of perinatal morbidity and mortality. The main purpose of this study is to explore maternal and fetal factors that predict the development of these obstetric complications, so that early medical interventions may be tested in patients at high- and low-risk for adverse perinatal outcomes.
- The NICHD Fetal Growth Study: Twin Gestations
Normal growth and development of twins are important for a healthy pregnancy and the long-term health of the fetuses. This study will assess how twins grow and develop inside the womb, establishing normative baselines to help guide clinicians in managing patients with twin pregnancies. In turn, this knowledge can help reduce or prevent problems for both mothers and infants.
NICHD Clinical Trials
ClinicalTrials.gov Search Results
Information on current NIH-sponsored clinical trials on obstetrics is available at the link below or by calling 800-411-1222.