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McCune-Albright Syndrome (MAS): Research Activities and Scientific Advances

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Institute Activities and Advances

The NICHD’s Program on Developmental Endocrinology and Genetics conducts research on McCune-Albright syndrome (MAS) and Cushing syndrome. This program studies genetic changes that affect the body’s endocrine system. The investigators have diverse backgrounds that range from biochemistry to molecular endocrinology and genetics to clinical obesity research.

The NICHD’s research on MAS includes, but is not limited to, the study of:

  • The cellular features of patients with MAS and Cushing syndrome
  • The association between MAS and pituitary gland tumors
  • The evaluation of gastrointestinal polyps in MAS patients

Other Activities and Advances

The NICHD also supports work related to MAS through the NICHD-NIDDK Interinstitute Endocrinology Training Program. This program seeks to train internal medicine physicians to become first-rate endocrinologists who seek investigative careers. This group’s research has explored:

  • The effect MAS has on the structure of thyroid cells
  • The prognostic features of patients with MAS and Cushing syndrome, as well as long-term follow-up treatment options
Last Updated Date: 11/30/2012
Last Reviewed Date: 11/30/2012
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