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Endometriosis: Clinical Trials

The NICHD conducts and supports a variety of clinical research related to endometriosis. Select a link below to learn more about these projects.

Featured NICHD Clinical Trials

Botulinum Toxin for Pelvic Pain in Women With Endometriosis

Some women with endometriosis have chronic pelvic pain that may be caused by spasms of the pelvic floor muscles, which can be identified by examination. Preliminary studies suggest that botulinum toxin may be able to treat these muscle spasms and reduce the associated pain. This study is testing to see if botulinum toxin injections into the pelvic floor muscles can decrease pain and spasms in women with pelvic pain.

Pelvic Pain in Women With Endometriosis.

This study, which is no longer recruiting participants, is examining pelvic pain associated with endometriosis and examining better approaches to treatment. Standard treatments-altering hormone levels to prevent endometrial tissue growth or surgically removing endometrial tissue-treat pelvic pain only temporarily. This study is investigating the role of sex hormones, immune chemicals, stress hormones, and genes in pelvic pain and trying to determine how the nerve, muscle, and skeletal systems are involved in this pain.

NICHD Clinical Trials

ClinicalTrials.gov Search Results

Information on current NIH-sponsored clinical trials on endometriosis is available at the link below or by calling 800-411-1222.

Last Updated Date: 11/30/2012
Last Reviewed Date: 11/30/2012
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Epidemiology Statistics and Prevention Branch Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology