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How many people are affected by or at risk for congenital adrenal hyperplasia (CAH)?

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Classic CAH occurs in about one of every 15,000 births worldwide.1

Nonclassic CAH is among the most common genetic disorders. It occurs in about one of every 1,000 people, but could occur in as many as 1 in 20 people in some communities.2 It is more common in Ashkenazi Jews, Hispanics, Italians, and Yugoslavians.3


  1. National Adrenal Diseases Foundation. (n.d.). CAH: Diagnosis. Retrieved April 25, 2012, from http://www.nadf.us/diseases/cah.htm#diagnosis External Web Site Policy [top]
  2. National Adrenal Diseases Foundation. (n.d.). CAH: Nonclassical. Retrieved April 25, 2012, from http://www.nadf.us/diseases/cah.htm#nonclassical External Web Site Policy [top]
  3. NIH Clinical Center. (n.d.). Patient education: Facts about CAH. Retrieved April 25, 2012, from http://www.cc.nih.gov/ccc/patient_education/pepubs/cah.pdf (PDF - 752 KB) [top]

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Last Updated Date: 07/31/2013
Last Reviewed Date: 07/09/2013
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology