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Amenorrhea: Clinical Trials

The NICHD conducts and supports a variety of clinical research projects related to uterine fibroids. Select a link below to learn more about these projects.

Featured NICHD Clinical Trials

  • Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes
    This trial aims to determine which changes in body composition and hormones differentiate athletes who stop getting their periods, athletes who continue to get their periods, and non-athletes. It also studies whether estrogen given as a pill or a patch (versus no estrogen) increases bone density and improves bone structure in adolescent athletes who are not getting their periods because of low estrogen.

  • Pulsatile GnRH in Anovulatory Infertility
    The trial will explore the effects of synthetic gonadotropin-releasing hormone (GnRH) upon the pituitary gland and the ovaries of women with infertility. Women diagnosed with GnRH deficiency, hypothalamic amenorrhea, acquired hypogonadic hypogonadism, or polycystic ovarian syndrome (PCOS) will participate in this study. Researchers hope the administration of GnRH will lead to proper stimulation of the pituitary gland and to normal ovulation and menstruation.

  • Ovarian Follicle Function in Patients with Premature Ovarian Failure
    No proven therapy to restore ovarian function and fertility is available to patients with karyotypically normal spontaneous premature ovarian failure. This study will evaluate patients and, if possible, determine suitability for therapeutic research protocols.

  • Inherited Reproductive Disorders
    This study will evaluate patients with reproductive disorders, including low hormone levels that delay or prevent puberty and the problem of precocious puberty, to learn how they may be inherited.

  • Gondanotropin Levels in Puberty and Fertility
    Researchers want to study patients with low levels or total lack of GnRH to better understand how it affects puberty and fertility.

NICHD Clinical Trials

ClinicalTrials.gov Search Results

Information on current NIH-sponsored clinical trials is available by following the link below or by calling 1-800-411-1222.

Last Updated Date: 11/30/2012
Last Reviewed Date: 03/03/2013
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Epidemiology Statistics and Prevention Branch Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology