Through its intramural and extramural organizational units, the NICHD supports and conducts a broad range of research on PCOS. Short descriptions of this research are included below.
The Institute's research focuses on genetic, molecular, and cellular mechanisms underlying PCOS as well as studies to determine precursors or predictors of PCOS in adolescents. The NICHD also supports and conducts studies on potential new treatments for PCOS, using animal models and human participants.
The Fertility & Infertility (FI) Branch is the NICHD's principal entity for the support of research on PCOS. One of the long-term goals of the FI Branch is to find more effective treatments for the symptoms of PCOS as well as other conditions associated with the disorder. Treatments of interest include both pharmacological and non-pharmacological interventions. The FI Branch is also interested in how individual factors like genetics affect responses to treatment. Other research includes demographic and risk information related to PCOS. Some FI Branch–supported findings include:
The Division of Intramural Research (DIR) also conducts research to advance understanding of the causes of PCOS. For example, the DIR Program on Developmental Endocrinology and Genetics is conducting a clinical trial to help determine if abnormal function of the adrenal glands contributes to elevated androgen levels and the development of PCOS in a subset of women. Researchers are currently looking for women to participate in this study. For more information on this research, visit http://clinicaltrials.gov/ct2/show/NCT01313455?term=NCT01313455&rank=1.
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