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Formal Title:






6100 EXECUTIVE BLVD Room 7B07H, MSC 7510
Bethesda Md 20892-7510
For FedEx use:
Rockville Md 20852

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Ruzong Fan, Ph.D, is an investigator in  Biostatistics and Bioinformatics Branch (BBB) of Division of Intramural Population Health Research (DIPHR), NICHD. He received his first Ph.D in Probability Theory  from Institute of Applied Mathematics, Chinese Academy of Sciences, Beijing in 1988; and his second Ph.D in biostatistics from University of Michigan -- Ann Arbor, 1998. Dr. Fan's research interests focus on statistical genetics, stochastic modeling, stochastic processes and applications.

Software of Statistical Genetics by Dr. Fan's group

Curriculum Vitae for Ruzong Fan in PDF (PDF - 74 KB)
Curriculum Vitae for Ruzong Fan in HTML


Publications (PubMed):

Title Authors Publication Date
Functional linear models for association analysis of quantitative traits.Fan R,Wang Y,Mills JL,Wilson AF,Bailey-Wilson JE,Xiong MGenet Epidemiol2013 Nov
Association analysis of complex diseases using triads, parent-child dyads and singleton monads.Fan R,Lee A,Lu Z,Liu A,Troendle JF,Mills JLBMC Genet2013 Sep 4
Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.Feenstra B,Geller F,Carstensen L,Romitti PA,Körberg IB,Bedell B,Krogh C,Fan R,Svenningsson A,Caggana M,Nordenskjöld A,Mills JL,Murray JC,Melbye MJAMA2013 Aug 21
A discussion of gene-gene and gene-environment interactions and longitudinal genetic analysis of complex traits.Fan R,Albert PS,Schisterman EFStat Med2012 Sep 28
Longitudinal Association Analysis of Quantitative Traits.Fan R,Zhang Y,Albert PS,Liu A,Wang Y,Xiong MGenet Epidemiol2012 Sep 10
Next generation analytic tools for large scale genetic epidemiology studies of complex diseases.Mechanic LE,Chen HS,Amos CI,Chatterjee N,Cox NJ,Divi RL,Fan R,Harris EL,Jacobs K,Kraft P,Leal SM,McAllister K,Moore JH,Paltoo DN,Province MA,Ramos EM,Ritchie MD,Roeder K,Schaid DJ,Stephens M,Thomas DC,Weinberg CR,Witte JS,Zhang S,Zöllner S,Feuer EJ,Gillanders EMGenet Epidemiol2012 Jan
Bivariate combined linkage and association mapping of quantitative trait loci.Jung J,Zhong M,Liu L,Fan RGenet Epidemiol2008 Jul
Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4.Yang Q,Biernacka JM,Chen MH,Houwing-Duistermaat JJ,Bergemann TL,Basu S,Fan R,Liu L,Bourgey M,Clerget-Darpoux F,Lin WY,Elston RC,Cupples LA,Apprey V,Cui J,Dupuis J,Ionita-Laza I,Li R,Lou X,Perdry H,Sherva R,Shugart YY,Suarez B,Wang H,Wormald H,Xing G,Xing CGenet Epidemiol2007
Haplotypes of the surfactant protein genes A and D as susceptibility factors for the development of respiratory distress syndrome.Thomas NJ,Fan R,Diangelo S,Hess JC,Floros JActa Paediatr2007 Jul
High-resolution association mapping of quantitative trait loci: a population-based approach.Fan R,Jung J,Jin LGenetics2006 Jan
Sibship T2 association tests of complex diseases for tightly linked markers.Fan R,Knapp MHum Genomics2005 Jun
Family-based association tests suggest linkage between surfactant protein B (SP-B) (and flanking region) and respiratory distress syndrome (RDS): SP-B haplotypes and alleles from SP-B-linked loci are risk factors for RDS.Floros J,Thomas NJ,Liu W,Papagaroufalis C,Xanthou M,Pereira S,Fan R,Guo X,Diangelo S,Pavlovic JPediatr Res2006 Apr
Combined linkage and association mapping of quantitative trait loci by multiple markers.Jung J,Fan R,Jin LGenetics2005 Jun
High resolution T association tests of complex diseases based on family data.Fan R,Knapp M,Wjst M,Zhao C,Xiong MAnn Hum Genet2005 Mar
Pedigree linkage disequilibrium mapping of quantitative trait loci.Fan R,Spinka C,Jin L,Jung JEur J Hum Genet2005 Feb
High-resolution joint linkage disequilibrium and linkage mapping of quantitative trait loci based on sibship data.Fan R,Jung JHum Hered2003
Linkage and association studies of QTL for nuclear families by mixed models.Fan R,Xiong MBiostatistics2003 Jan
Genome association studies of complex diseases by case-control designs.Fan R,Knapp MAm J Hum Genet2003 Apr
Combined high resolution linkage and association mapping of quantitative trait loci.Fan R,Xiong MEur J Hum Genet2003 Feb
Association studies of QTL for multi-allele markers by mixed models.Fan R,Jung JHum Hered2002
High resolution mapping of quantitative trait loci by linkage disequilibrium analysis.Fan R,Xiong MEur J Hum Genet2002 Oct
Is low iron status a risk factor for neural tube defects?Molloy AM,Einri CN,Jain D,Laird E,Fan R,Wang Y,Scott JM,Shane B,Brody LC,Kirke PN,Mills JLBirth Defects Res A Clin Mol Teratol2014 Feb
Genotype-based association mapping of complex diseases: gene-environment interactions with multiple genetic markers and measurement error in environmental exposures.Lobach I,Fan R,Carroll RJGenet Epidemiol2010 Dec
A powerful score test to detect positive selection in genome-wide scans.Zhong M,Lange K,Papp JC,Fan REur J Hum Genet2010 Oct
A genome-wide association scan for rheumatoid arthritis data by Hotelling's T2 tests.Chen L,Zhong M,Chen WV,Amos CI,Fan RBMC Proc2009 Dec 15
Quantitative trait loci for exercise training responses in FVB/NJ and C57BL/6J mice.Massett MP,Fan R,Berk BCPhysiol Genomics2009 Dec 30
Transmission of surfactant protein variants and haplotypes in children hospitalized with respiratory syncytial virus.Thomas NJ,DiAngelo S,Hess JC,Fan R,Ball MW,Geskey JM,Willson DF,Floros JPediatr Res2009 Jul
Combined linkage and association mapping of quantitative trait Loci with missing completely at random genotype data.Fan R,Liu L,Jung J,Zhong MBehav Genet2008 May
Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.Deac OM,Mills JL,Shane B,Midttun Ø,Ueland PM,Brosnan JT,Brosnan ME,Laird E,Gibney ER,Fan R,Wang Y,Brody LC,Molloy AMJ Nutr2015 Apr
Pleiotropy Analysis of Quantitative Traits at Gene Level by Multivariate Functional Linear Models.Wang Y,Liu A,Mills JL,Boehnke M,Wilson AF,Bailey-Wilson JE,Xiong M,Wu CO,Fan RGenet Epidemiol2015 Mar 23
Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects.Mills JL,Fan R,Brody LC,Liu A,Ueland PM,Wang Y,Kirke PN,Shane B,Molloy AMAm J Clin Nutr2014 Oct
Novel copy-number variants in a population-based investigation of classic heterotaxy.Rigler SL,Kay DM,Sicko RJ,Fan R,Liu A,Caggana M,Browne ML,Druschel CM,Romitti PA,Brody LC,Mills JLGenet Med2014 Sep 18
Generalized functional linear models for gene-based case-control association studies.Fan R,Wang Y,Mills JL,Carter TC,Lobach I,Wilson AF,Bailey-Wilson JE,Weeks DE,Xiong MGenet Epidemiol2014 Nov
Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5'-Phosphate Concentration in Healthy Adults.Carter TC,Pangilinan F,Molloy AM,Fan R,Wang Y,Shane B,Gibney ER,Midttun Ø,Ueland PM,Cropp CD,Kim Y,Wilson AF,Bailey-Wilson JE,Brody LC,Mills JLJ Nutr2015 May 13
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology