In collaboration with our colleagues in the research, public health, and public policy communities, as well as those in professional societies and advocacy groups, the Institute embarked on a process to identify the most promising opportunities of the next decade across the breadth of the science that the NICHD mission encompasses. The culmination of this process is a scientific Vision that sets an ambitious agenda and inspires the NICHD and our many collaborators to achieve new goals.The NICHD scientific Vision outlines a future that requires cross-Institute, cross-agency, cross-discipline, and international collaboration. The scientific Vision capitalizes on best practices and technologies while encouraging innovation and creativity; it addresses issues at both the macro- and micro-levels; and calls upon all of us to expand our horizons and expectations.Implementing the NICHD scientific Vision will entail writing new chapters in the Institute's story and in the science that brings us together. This effort will compel us to approach challenges together—bringing all of our passions and expertise to bear on the health and human development questions that lie ahead. Our mission is ennobling. Our possibilities are exciting.