The Section on Reproductive Medicine, headed by Lynnette Nieman, works on the hypothalamic pituitary adrenal axis in pregnancy, which complicates differential diagnosis of Cushing's syndrome, and on assessing the relative merits of immunometric and radioimmunoassay measurement of ACTH for diagnosis. The Section continues its work on the diagnosis and management of patients with hypercortisolism, recently focusing on ectopic ACTH-secreting tumors and their localization. Another focus of the Section s work is endometrial physiology and endometriosis pathologies, publishing studies on the endometrium, describing the localization of lesions in women with endometriosis, and use of raloxifene as an adjunct treatment for endometriosis. The Section found that staining of CD10, a cell-surface metalloendopeptidase present in normal endometrium, is helpful in diagnosing endometriosis.
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