Rajeshwari Sundaram, Ph.D., M.Stat.

Current Position:

Investigator, Biostatistics & Bioinformatics Branch
Division of Epidemiology, Statistics & Prevention Research
Eunice Kennedy Shriver National Institute of Child Health

& Human Development
The National Institutes of Health

Address:

6100 Executive Blvd., Room 7B05
Rockville, Maryland 20852
301-435-6953
301-402-2084 (fax)
sundaramr2@mail.nih.gov

Education:

1994-1999 Ph.D., Statistics, Michigan State University, East Lansing
1991-1993 M.Stat. (Applied Statistics & Data Analysis), Indian Statistical Institute, Kolkata
1988-1991 B.Sc. (Honors), Mathematics, University of Calcutta, India

Research Interests:

Work Experience:

Research projects:

Principal Investigator, Eunice Kennedy Shriver National Institute of Child Health and Human Development

2011-2012 Validation Study of Retrospectively Reported Time-to-Pregnancy Data, LIFE Study; $356,359

Lead Statistician and Co-Investigator, Eunice Kennedy Shriver National Institute of Child Health and Human Development

2004-2010 Longitudinal Investigation of the Environment and Fertility (LIFE Study); $11,000,000
2006-2009 Stress and Time to Pregnancy, Oxford Conception Study; $107,000
2007-2011 Upstate KIDS Study; $7,560,993
2011-2012 Air Quality and Women’s Reproductive Health. (LIFE Study and Consortium on Safe Labor Study), $494,458
2014-2019 Upstate KIDS CVD Follow-Up, $5,197,696 (tentative)

Co-Investigator, Eunice Kennedy Shriver National Institute of Child Health and Human Development

2006-2010 Persistent Environmental Compounds and Gynecologic Health (ENDO Study); $5,300,000

Awards:

Grants:

Teaching:

At NICHD:

Mentoring:

At UNC-Charlotte:

Graduate courses taught

Undergraduate courses taught

Mentoring

Master's Projects Supervised:

Professional Service:

At NICHD

At UNC-Charlotte

Adhoc Reviewer for Biometrics, Statistics in Medicine, Journal of Statistical Planning and Inference, Human Reproduction, Environmental Health Perspective, Statistical Methodology

Grand Rounds

Invited Talks

Oral Presentations at Scientific meetings

Refereed Manuscripts:

* denotes mentored paper.

  1. Rougoor CW, Sundaram, R, van Arendonk JAM. The relation between breeding management and 305-day milk production, determined via principal components regression and partial least squares. Livestock Production Science, 2000; 66: 71-83.

  2. Sundaram R. Estimation of scale parameter based on doubly censored samples. Journal of Statistical Planning and Inference, 2003; 115: 657-681.

  3. Brandon W, Troyer J, Sundaram R, Sun Y, Schoeps N, Walsh B. Medicaid enrollee switching among managed care plans. Journal of Health Care for the Poor and Underserved, 2005; 16:760-779.

  4. Sundaram R. Semi-parametric Inference in Proportional Odds Model with time-dependent covariates. Journal of Statistical Planning and Inference, 2006;136:320-334.

  5. Sundaram R. Estimation in two sample randomly truncated scale model. Journal of Statistical Planning and Inference, 2006; 136:2983-3006.

  6. Biswas A, Sundaram R. Kernel Survival function estimation based on doubly censored data. Communications in Statistics, Theory and Methods, 2006; 35:1293-1307. Authorship in alphabetical order.

  7. Datta S, Sundaram R. Nonparametric marginal estimation in a multistage model using current status data. Biometrics, 2006; 62: 829-837. Authorship in alphabetical order.

  8. Sundaram R. Robust Analysis of Recurrent Events in presence of terminal events. Invited paper for “Statistical Advances in the Bio-Medical Sciences: State of the art and future directions”, edited by Datta, Segal, Fine, Biswas; John Wiley and Sons, NJ, 2007.

  9. Sundaram R. Semi-parametric Inference in Proportional Odds Model with randomly truncated data. Journal of Statistical Planning and Inference, 2009; 139: 1381-1393.

  10. Sundaram R. Estimation in two sample randomly truncated scale model. Virtual Special Issue: Biostatistics & Statistical Bioinformatics, Elsevier Statistics Journal, 2008.

  11. Chang M, Parker E, Muller T, Haenen C, Mistry M, Finkielstain G, Murphy-Ryan M, Barnes K, Sundaram R, Baron J. Changes in cell cycle kinetics responsible for limiting somatic growth in mice. Pediatric Research 64: 240-245, 2008.

  12. Cooney M, Buck Louis G, Sundaram R, McGuiness BJ, Lynch CD. Validity of Self Reported Time-to-Pregnancy. Epidemiology 20: 56-59, 2008.

  13. Zhang J, Sundaram R, Sun W, Troendle J. Fetal Growth and Spontaneous Onset of Labor in Humans. American Journal of Epidemiology 168: 946-951, 2008.

  14. Brandon W, Sundaram R, Dunham A. Multiple switching in Medicaid managed care: A Proportional Hazards Model. Journal of Health Care for Poor and Underserved 20:1124-1141, 2009.

  15. Datta S, Lan L, Sundaram R. Nonparametric estimation of waiting time distributions in a Markov model based on current status data. Journal of Statistical Planning and Inference 13:2885-2897, 2009. Authorship in alphabetical order.

  16. *Hyun S, Sun Y, Sundaram. Assessing Cumulative Incidence Functions under the Semi-parametric Additive Risk Model. Statistics in Medicine 28:2748-2768, 2009.

  17. Sun Y, Sundaram R, Zhao Y. Empirical likelihood inference for the Cox model with time-dependent coefficients via local partial likelihood. Scandinavian Journal of Statistics 6:444-462, 2009. Authorship in alphabetical order.

  18. *Kim SD, Sundaram R, Louis GB. Joint modeling of intercourse behavior and human fecundability using Structural equation models. Biostatistics 11: 559-571, 2010.

  19. *Mikolajczyk R, Louis GB, Cooney M, Lynch C, Sundaram R. Characteristics of prospectively measured vaginal bleeding among women trying to conceive. Paediatric and Perinatal Epidemiology 24: 24-30, 2010.

  20. Murphy L, Gollenberg A, Louis GB, Kostyniak J, Sundaram R. Pre-Conception Polychlorinated Biphenyl Exposure and Infant Birth Weight. Environmental Health Perspectives 118: 297-302, 2010.

  21. Neta G, von Ehrenstein O, Lum K, Sundaram R, Zhang J. Risk association of cord blood cytokines with preterm delivery and small for gestational age infants. American Journal of Epidemiology 171:859-867, 2010.

  22. *Pollack A, Louis GB, Sundaram R, Lum K. Caffeine Consumption and Pregnancy Loss. Fertility and Sterility 93: 304-306, 2010.

  23. Zhang J, Troendle J, Mikolajczyk R, Sundaram R, Beaver J, Fraser W. The 1st Stage of Labor: 1959 – 1966. Obstetrics & Gynecology 115:705-710, 2010.

  24. Bloom M, Louis GMB, Sundaram R, Kostyniak J, Jain J. Metals and fecundity. Reproductive Toxicology 31:158-63, 2011.

  25. Buck Louis GM, Schisterman EF, Sweeney AM, Wilcosky TC, Gore-Langton R E, Lynch CD, Barr DB, Schrader SM, Kim S, Chen Z and Sundaram R. Designing Prospective Cohort Studies for Assessing Reproductive and Developmental Toxicity during Sensitive Windows of Human Reproduction and Development - the LIFE Study. Paediatric and Perinatal Epidemiology 25:413-424, 2011.

  26. Buck Louis GM, Rios LI, McLain A, Cooney M, Kostyniak P and Sundaram R. Persistent organochlorine pollutants and menstrual cycle length. Chemosphere 85(11):1742-8, 2011.

  27. Buck Louis GM, Lum K, Sundaram R, Chen Z, Kim S, Lynch C, Schisterman, EF and Pyper C. Stress reduces conception probabilities across the fertile window: Evidence in support of relaxation. Fertility and Sterility 95(7):2184-2189, 2011.

  28. Gollenberg A, Cooney M, Mumford S, Sundaram R, Louis GB. Validity of retrospectively reported behaviors during the periconception window. Journal of Reproductive Medicine Mar-Apr; 56(3-4):130-7, 2011.

  29. Louis GMB, Hediger M, Peterson M, Croughan M, Sundaram R, Stanford J, Chen Z, Fujimoto V, Varner M, Trumble A, Giudice L. Incidence of endometriosis by study population and diagnostic method: the ENDO Study. Fertility and Sterility 96:360-365, 2011.

  30. Louis GMB, Schisterman EF, Sweeney A, Wilcosky T, Gore-Langton R, Lynch C, Barr D, Schrader S, Kim SD, Chen Z, Sundaram R. Designing Prospective Cohort Studies for Assessing Reproductive and Developmental Toxicity during Sensitive Windows of Human Reproduction and Development- The LIFE Study. Paediatric and Perinatal Epidemiology 25:413-424,2011.

  31. *Lum K, Sundaram R, Louis GB. Women’s lifestyle behaviors while trying to become pregnant: evidence supporting preconception guidance. Am. J. Obstet. Gynecol. 205(3):203.e1-7, 2011.

  32. *McLain AC, Sundaram R., Cooney MA, Gollenberg AL, Buck Louis GM. Clustering of fecundability within women. Paediatric and Perinatal Epidemiology 25: 460–465, 2011.

  33. Buck Louis GM, Sundaram R, Schisterman EF, Sweeney AM, Lynch CD, Gore- Langton RE, Chen Z, Kim S, Caldwell K, & Barr DB. Heavy Metals and Couple Fecundity, the LIFE Study. Chemosphere 87:1201-1207, 2012.

  34. Kunisue T, Chen Z, Louis GMB, Sundaram R, Hediger ML, Sun L, Kannan K. Urinary Concentrations of Benzophenone-type UV Filters in the US Women from Two Cities and Their Association with Endometriosis. Environmental Science and Technology 46:4624-4632, 2012.

  35. Laughon SK, Zhang J, Grewal J, Sundaram R, Beaver J, Reddy U. Induction of Labor in Contemporary Obstetric Practice. Am. J. Obstet Gynecol 206:486.e1-9, 2012

  36. Louis GMB, Chen Z, Peterson CM, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Varner MW, Fujimoto VY, Giudice LY, Trumble A, Parsons PJ, Kannan K. Persistent Lipophilic Environmental Chemicals and Endometriosis: The ENDO Study, 2007-2009. Environmental Health Perspectives 120:811-816, 2012.

  37. Louis GMB, Chen Z, Peterson CM, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Varner MW, Fujimoto VY, Giudice LY, Trumble A, Parsons P J, Kannan K. Perfluorochemicals and Endometriosis: The ENDO Study. Epidemiology (in press)..

  38. Lynch CD, Sundaram R, Buck Louis GM, Lum KJ, Pyper C. Are increase levels of self-reported psychosocial stress, anxiety, and depression associated with fecundity? Fertility and Sterility (in press).

  39. *McLain AC, *Lum K., Sundaram R. A joint mixed effects dispersion model for menstrual cycle length and time-to-pregnancy. Biometrics, 68:648-656, 2012.

  40. *McLain AC, Sundaram R, Louis GMB. Modeling time to pregnancy in presence of sterile fraction using transformation survival model. Statistical methods in medical research (in press).

  41. Sundaram R, McLain A, Louis Buck G. A survival analysis approach to modeling human fecundity. Biostatistics. 13:4-17, 2012.

  42. Chason R, McLain AC, Sundaram R, Chen Z, Segars JH, Pyper C, Louis GMB. Preconception Stress and the Secondary Sex Ratio: A Prospective Cohort Study. Fertility and Sterility (in press).

  43. Thoma ME, Hediger ML, Sundaram R, Stanford JB, Peterson CM, Croughan MS, Chen Z, Louis GMB and the ENDO Study. Comparing “Apples and Pears:” Women’s perceptions of their body size and shape. Journal of Women’s Health (in press).

  44. *Kim SD, Sundaram R, Louis GMB. Flexible Bayesian Human Fecundity Models. Bayesian Analysis (in press). Invited for discussion.

  45. Louis GMB, Sundaram R, Schisterman, E., Maisog, J., Kim, S. D., Chen, Z., Sweeney, A. Persistent organochlorine compounds and Time to pregnancy. Environmental Health Perspectives (provisionally accepted).

Book Chapters:

  1. Sundaram R, Balakrishnan N. Semi-parametric inference for competing risks data. Methods and applications of statistics in life and health sciences, Chapter 67, 749-765, Eds. Balakrishnan, N. Read, C. B., Vidakovic, B., Kotz, S., Johnson, N. L.; John Wiley and Sons, NJ, 2009.

  2. Sundaram R, Louis GMB, Kim SD. Statistical modeling of human fecundity. Methods and applications of statistics in life and health sciences, Chapter 73, pages 815833, Eds. Balakrishnan, N. Read, C. B., Vidakovic, B., Kotz, S., Johnson, N. L.; John Wiley and Sons, NJ, 2009.

  3. Louis GMB, Sundaram R. Exposome: time for transformative research. Statistics in Medicine (in press).

  4. Albert PS, Sundaram R, McLain A. Innovative approaches to analyzing longitudinal data with missingness using shared parameter models. Lecture notes in Statistics.

Manuscripts under review:

  1. *Mclain AC, Sundaram R, Louis GMB. Prediction of longitudinal binary data with informative dropout: A joint modeling approach.

  2. Laughon SK, McLain AC, Sundaram R, Catov J, Louis GMB. Maternal lipid change in relation to length of gestation: a prospective cohort study with preconception enrollment of women.

  3. Thoma ME, McLain AC, Louis JF, King RB, Trumble A, Sundaram R, Louis GMB. The prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach.

  4. Sundaram R, Lynch C, Kissell K, Mclain AC, Pyper C, Louis GMB. Stress and menstrual cycle characteristics.

Manuscripts in preparation:

  1. Sundaram R, Ghoshal S, Mclain AC. Statistical inference of median cost associated with recurrent hospitalizations in presence of terminal event.

  2. Lynch C, Sundaram R, Maisog J, Sweeney A, Louis GMB. Increased levels of physiologic stress are associated with decreased fecundability: results from a couple-based prospective study, The LIFE Study.

  3. Mumford S, Sundaram R, Schisterman E, Maisog J, Chen Z, Kim S, Sweeney A, Louis GMB. Phytoestrogens and time-to-pregnancy.

  4. Katki H, Sundaram R, Wacholder S. A joint model of HPV tests and cervical cancer for potential use in developing cancer screening guidelines.

Work in progress:

  1. Sundaram R, Biswas A, Grewal J, Laughon S, Reddy U. A multistage model approach to modeling functional data, with application to human labor curves.

  2. Lum K, Sundaram R, Louis T. Incorporating Sampling Plan and Competing Risks in Analysis of Prospective Pregnancy Studies.

  3. *Nsoesie E, Sundaram R. Modeling digit preference in self-reported data in pregnancy studies.

  4. Sundaram R, Louis GMB. Accounting for heterogeneous fertile window in modeling fecundability.

  5. Sundaram, R. Louis, G.M.B. An elastic-net approach to variable selection with discrete survival data: An application to chemicals and time to pregnancy studies.