James Louis Mills, M.D., M.S.

October 2014

Current Position

Senior Biomedical Research Service Scientist
Senior Investigator
Eunice Kennedy Shriver National Institute of Child Health and
Human Development
National Institutes of Health
2000-present

Address

Epidemiology Branch
Division of Intramural Population Health Research
6100 Executive Boulevard, Room 7B03
Bethesda, Maryland 20892
Voice: (301) 496-5394
FAX: (301) 402-2084
E-mail: jamesmills@nih.gov

Education

University of Pennsylvania: 1965-1969
Degree: Bachelor of Arts, with Distinction, 1969
Major: History -Pre Med

New York Medical College: 1969-1973
Degree: Doctor of Medicine, 1973

University of Pennsylvania: 1978-1979
Degree: Master of Science, 1979
Course: Epidemiology

Academic & Research Experience

Chief, Pediatric Epidemiology Section
Epidemiology Branch
Division of Epidemiology, Statistics, and Prevention Research
National Institute of Child Health and Human Development
1990-2006 (sections eliminated in restructuring, 2006)

Senior Investigator (Research Medical Officer, GS-13, GS-14 and GS-15)
National Institute of Child Health and Human Development
National Institutes of Health
1982-1999

Medical Staff Fellow
National Institute of Child Health and Human Development
National Institutes of Health
1979-1982

Post Graduate Training and Fellowship Appointments

Pediatric Resident, The New York Hospital
Cornell University Medical Center, 1973-1975

Fellow in Ambulatory Pediatrics, Children's
Hospital of Philadelphia, 1975-1976

Fellow in Endocrinology, Children's Hospital
of Philadelphia, 1976-1979 Robert Wood Johnson Clinical Scholar
University of Pennsylvania, 1976-1979

Faculty Appointments

Fellow: Department of Pediatrics
Cornell University School of Medicine, 1974-1975

Post-Doctoral Fellow: Department of Research Medicine
University of Pennsylvania, 1976-1979

Attending Pediatric Endocrinologist: Clinical Center
National Institutes of Health 1979-1995

Attending Pediatrician: Clinical Center
National Institutes of Health 1981-1984

Lecturer: Department of Epidemiology
The Johns Hopkins University, 1982-1985

Associate: Department of Epidemiology
The Johns Hopkins University, 1985-present

Consultant Pediatric Endocrinologist: National Naval Medical Center 1985-2005

Medical Certification

Diplomate: National Board of Medical Examiners, 1974
Specialty Certification: American Board of Pediatrics, 1978
Sub-Specialty Certification: American Board of Pediatrics, Pediatric Endocrinology Sub-Board, 1980
Licensure: New York Pennsylvania

Professional Societies

American Epidemiological Society
American Pediatric Society
Pediatric Endocrine Society
Society for Pediatric Research
American College of Epidemiology
Teratology Society

Other Professional Training and Experience

Research Assistant, Laboratory of Human Genetics, New York Medical College, 1970-1971

Fellow in Tropical Medicine, International Center for Medical Research and Training, National Institutes of Health, San Jose, Costa Rica, 1972

Graduate Student in Health Care Administration, The Wharton School, University of Pennsylvania, 1976-1977

Pediatrician, Medical Associates, Children's Hospital of Philadelphia, 1977-1979 Consultant Endocrinologist, Ortho Pharmaceutical Corporation and Paul D. Stolley, M.D. Study of Estrogen Effects in Oral Contraceptive Workers, 1978-1979

Scientific Review Service (since 2000)

Journal Reviewer

New England Journal of Medicine (frequent reviewer)
JAMA
The Lancet
American Journal of Epidemiology
American Journal of Obstetrics and Gynecology
American Journal of Medical Genetics
Birth Defects Research-A
American Journal of Clinical Nutrition
Pediatrics
Pediatric and Perinatal Epidemiology
Others-this is not something I systematically record

Extramural Grant Review

Reviewer, Center For Inherited Disease Research, Gene Environment and Health Initiative Study, Technical Advisory Group, Bethesda, MD, October, 2007.

Planning Committees – Workshops, Annual Meetings, Training

Symposium Chair and Organizer, Public Affairs Committee Symposium– Birth Defects and Other Adverse Pregnancy Outcomes Due to Obesity. Teratology Society, Vancouver, BC. June 2004.

Invited Speaker, Congenital Malformations. ART Children’s Health: A Systematic Review. Workshop. American Society for Reproductive Medicine. Philadelphia, PA. October 2004.

Planning Committee, Teratology Society Annual Meeting, Monterey, CA. June 2008.

Planning Committee, Teratology Society Annual Meeting, Rio Mar, PR, June 2009

Planning Committee, NHANES Monitoring of Biomarkers of Folate and Vitamin B12 Status, 2009-2010

Organizer, Symposium: Vitamin B12 Deficiency and Neural Tube Defects. Teratology Society, Louisville, KY, June 2010.

Committees, Advisory Boards and Other Professional Services

Member, Second Structural Birth Defects Meeting, NICHD, Bethesda, December 2002. Invited Expert, US Food and Drug Administration Pregnancy Labeling Subcommittee Meeting on Pregnancy Registries, Rockville, MD, February 2000

Participant/ Invited Speaker, Advisory Committee for Reproductive Health Drugs, Food and Drug Administration - Adding folic acid to oral contraceptives, December, 2003.

Advisor, US Food and Drug Administration. Division of Reproductive and Urologic Products. Silver Spring, MD, March, 2006.

Deputy Director for Intramural Research Representative, BSC review, Radiation Oncology Branch, NCI 2010

Public Affairs Committee. Teratology Society 2010-2013

Vaccines and Medications in Pregnancy Surveillance Systems, American Academy of Allergy, Asthma and Immunology, Advisory Committee Member, 2010-present

NICHD Member and Executive Secretary. Data Safety Monitoring Board, CHEF Study. 2010-present

Expert Reviewer. Technical Assistance Package—CDC to FDA. Corn Masa Flour Fortification

Judge for the Marcy Speer Pre and Post Doctoral Research Awards. 7th International Conference on Neural Tube Defects, Nov. 2011.

Biomarkers of Nutrition for Development (BOND) Folate Expert Panel Member. 2012-2013

March of Dimes Consultant. Stillbirths 37 to 39 Weeks. December 2012.

March of Dimes Research Advisory Committee A. Grant reviewer. February 2013.

March of Dimes Gene Discovery and Translational Grants Advisory Committee. Grant reviewer. February 2014.

Teratology Society. Mentor “Ambassador Program”. June 2014

Invited Keynotes, Talks and Seminars

Invited Speaker, Slone Memorial Lecture, Slone Epidemiology Unit, Boston University, Boston, MA. April 2000

Faculty Member, Harvard Medical School Continuing Education Course on Human Teratogens, Boston, MA. April 2000.

Invited Speaker, Medical Grand Rounds, University of Pittsburgh, Pittsburgh, PA. Sept. 2000.

Invited Speaker, Plenary Session, Congress of Genetics and Molecular Medicine of Mexico, Monterrey, Mexico, Oct. 2000.

Expert Panel Member, Expert Panel on Periconceptional Folic Acid Use to Prevent Congenital Malformations, Budapest, Hungary. April 2001.

Invited Speaker, Slone Memorial Lecture, Slone Epidemiology Unit, Boston University, Boston, MA. April 2000

Faculty Member, Harvard Medical School Continuing Education Course on Human Teratogens, Boston, MA. April 2000.

Invited Speaker, Medical Grand Rounds, University of Pittsburgh, Pittsburgh, PA. Sept. 2000.

Invited Speaker, Plenary Session, Congress of Genetics and Molecular Medicine of Mexico, Monterrey, Mexico, Oct. 2000.

Expert Panel Member, Expert Panel on Periconceptional Folic Acid Use to Prevent Congenital Malformations, Budapest, Hungary. April 2001.

Plenary Session Speaker, Charting the Course, Birth Defects, Developmental Disabilities, and Disability and Health. CDC, Atlanta, September, 2002.

Guest speaker, Clinical Nutrition Research Center, University of Alabama, Birmingham, November,2002.

Invited Speaker, Folic Acid-Beyond the Prevention of Neural Tube Defects. American College of Preventive Medicine, Orlando, FL. February 2004.

Invited Speaker, Current Topics in Neonatal/Infant Nutrition and Metabolism V. Methionine, Methylation and Epigenetics. Houston, TX. January 2005.

Invited Speaker, The Intrauterine Environment: Long-term Consequences of Obesity and Metabolic Disease Conference. Maternal Obesity and Birth Defects. Bethesda, MD. September, 2005.

Invited Speaker, Folic Acid and Neural Tube Defects. Pediatric Neurology Grand Rounds, Johns Hopkins School of Medicine, Baltimore, MD, October, 2006.

Invited Speaker, Careers in Washington, D.C.- Medical Research. University of Pennsylvania, Philadelphia, PA, February, 2007.

Invited Speaker, Neural Tube Defects and Folic Acid: The Science and The Controversy, Benjamin Franklin Scholars Program, University of Pennsylvania, Philadelphia, PA, February, 2007.

Invited Speaker, Food Fortification with Folic Acid: Effects and Side Effects. Organization of Teratology Information Specialists/Teratology Society Joint Meeting. Monterey, CA, June 2008.

Invited Speaker, Maternal Obesity and Congenital Heart Defects. Coordinating Committee, NICHD National Child and Maternal Health Education Program, Bethesda, MD. Jan. 2012

Invited Keynote Speaker and Session Chair, 9th International Conference on Homocysteine and One-carbon Metabolism, Dublin, Ireland September 2013.

Invited Workshops and Panel Discussions

Workshop Member, WHO Conference on International Collaborative Studies on the Prevention of Cranio-facial Abnormalities, Park City, Utah. May 2001.

Session Chair, NIH Structural Birth Defects Investigators Meeting, Bethesda, Maryland. July 2001.

Advisor, Centers for Disease Control and Prevention Neural Tube Defects-Folic Acid Intake Meeting (Evaluation of Data from NBDPS), Atlanta, GA, August, 2007.

Session Chair, Teratology Society Annual Meeting. Monterey, CA, June 2008.

Invitee, Challenges and Opportunities in Using Newborn Screening Samples for Translational Research: A Workshop. Institute of Medicine Roundtable on Translating Genomic-Based Research for Health, Washington, DC, May 2010.

Participant, Optimizing Folic Acid/Folate Awareness and Intake in High-Risk Women Roundtable. March of Dimes, Bayer Health Care Pharmaceuticals, Washington, DC, June 2010.

Invited Participant, Birth Defect Gene Research Conference (CDC), Washington, DC 2010

Invited Panel Member: NHANES Monitoring of Biomarkers of Folate and Vitamin B12 Status, 2010.

Faculty Member, Harvard Medical School Continuing Education Course on Human Teratogens, Boston, MA. April 2011.

Speaker, Mary Frances Picciano Dietary Supplements Research Practicum. Folate and Folic Acid. NIH. Folate and Folic Acid. June 2011.

Speaker, Mary Frances Picciano Dietary Supplements Research Practicum. NIH. Folate and Folic Acid. June 2012.

Faculty Member, Harvard Medical School Continuing Education Course on Human Teratogens, Boston, MA. April 2013.

Speaker, Mary Frances Picciano Dietary Supplements Research Practicum. NIH. Folate and Folic Acid. June 2013.

Speaker, Mary Frances Picciano Dietary Supplements Research Practicum. NIH. Folate and Folic Acid. June 2014.

Presentations at Scientific Meetings (as presenter)

Speaker and Panel Member, Consensus Conference on the Safe and Optimal Use of Isotretinoin, American Academy of Dermatology, New Orleans, Louisiana. February, 2002.

Speaker, Long-term Mortality in the U.S. Cohort of Pituitary Growth Hormone Recipients. American Epidemiological Society. New York, NY, March 2002.

Invited Speaker, Assisted Reproduction Technology and Reproductive Problems: What are the facts and Issues? Teratology Society, Phila. Pa. June 2003.

Invited Discussant, Selected Gene Polymorphisms of Possible Vascular Impact, and Their Interaction with Maternal Smoking, As Risk Factors for Gastroschisis. Teratology Society. St. Pete Beach, FL. June 2005.

Speaker, Maternal Obesity and Congenital Heart Defects. American Epidemiological Society, Baltimore, MD, March 2010.

Speaker, Vitamin B12 Deficiency and Neural Tube Defects: Is There a Causal Relationship? Teratology Society, Louisville, KY, June 2010.

Invited Speaker, NIAAA Collaborative Initiative on FASD. Feb. 2011.

Speaker, American Epidemiological Society. Do high blood folate levels exacerbate the metabolic abnormalities in people with low vitamin B12 levels? March 2011

Platform presentation, Free and total choline levels during pregnancy and neural tube defects. 7th International Conference on Neural Tube Defects, Nov. 2011.

Speaker, American Epidemiological Society. Choline: An “essential nutrient”, but is it essential to prevent neural tube defects? March 2012

Speaker, American Epidemiological Society. Food fortification produces unmetabolized folic acid in serum. March 2013.

Speaker, American Epidemiological Society. Obesity and Congenital Heart Defects, March 2014

Awards and Honors

General Honors Program, University of Pennsylvania, 1965
Graduation with Distinction in History, University of Pennsylvania, 1969
National Institutes of Health Student Fellowship for the Study of Tropical
Medicine, 1972
Robert Wood Johnson Clinical Scholar, 1976
Fellow, Leonard Davis Institute, 1978
Elected to Society for Pediatric Research, 1984
Elected-Fellow, American College of Epidemiology, 1987
Selected for American Men and Women of Science, 1988
NIH Director's Award (NIH's Highest Award) for Birth Defects Research, 1989
NIH Special Act or Service Award for Research on Neural Tube Defects, 1990
Elected to American Pediatric Society, 1991
Elected to American Epidemiological Society, 1991
U.S. Public Health Service Special Recognition Award for Risks and Benefits of Fluoride Report, 1992.
Selected Speaker for University of Pennsylvania Distinguished Alumni-Faculty
Lecture, 1994
Invited Speaker, Congressional Biomedical Research Caucus, 1995
AAll-Time Top NICHD Accomplishments@ Two projects among the 36 most important research achievements (intramural and extramural) in NICHD history, 1998
Richard K. Miller Lecturer, University of Rochester, 1999
Slone Memorial Lecturer, Boston University, 2000
NIH Director's Award for Research on Folate Metabolism and Birth Defects, 2000
Author of one of four Papers Selected As “Classic Papers” from 50 years of publications in the journal of the Teratology Society 2010
Centers for Disease Control and Prevention. Special Act or Service Award. “In recognition of your contribution to the health of children by providing scientific expertise to the assessment of the safety of folic acid” 2011.

Patent

Materials and methods associated with polymorphic variants in two enzymes involved in folate-dependent and one-carbon metabolic pathways. Diagnostic and therapeutic methods are provided involving the correlation of polymorphic variants in MTBFD1, MTHFD1, and other genes with relative susceptibility for various pregnancy-related and other complications. US7879551 External Web Site Policy

Mentoring

NIH Summer Interns

Laura Kresch, epidemiology graduate student
Isabelle Von Kohorn, medical student
Homa Khorrami, medical student
Irene Woo, medical student
Joshua Cornman-Homonoff, medical student

NIH IRTAs

Lucinda England, MD, MPH
Caroline Signore, MD, MPH
Elizabeth Flanigan, MD, MPH
Tonia Carter, PhD
Devon Kuehn, MD
Shannon Rigler, MD
Angela Dimopoulos, MD
Erin Hagen, B.S.

Publications

Refereed Manuscripts

  1. Mills JL, Baker L, Goldman A. Malformations in infants of diabetic mothers occur before the seventh gestational week: Implications for therapy. Diabetes 1979; 28:292-293.
  2. Mills JL, Spackman T, Borns P, Mandell G, Schwartz W. The usefulness of lateral neck radiographs in laryngotracheobronchitis. Am J Dis Child 1979; 133:1140-1142.
  3. Bahn A, Mills JL, Snyder P, Gann P, Houten L, Bialik O, Hollmann L, Utiger R. Hypothyroidism in workers exposed to polybrominated biphenyls. N Engl J Med 1980; 302:31-33.
  4. Mills JL, Harlap S, Harley E. Should coitus late in pregnancy be discouraged? Lancet 1981; 2:136-138.
  5. Mills JL, Stolley P, Davies J, Moshang T. Premature Thelarche: Natural history and etiologic investigation. Am J Dis Child 1981; 135:743-745.
  6. Stanley C, Mills JL, Baker L. Intragastric feeding in type I glycogen storage disease: Factors affecting the control of lactic acidemia. Pediatr Res 1981; 15:1504-1508.
  7. Mills JL. Malformations in infants of diabetic mothers. Teratology 1982; 25:385-394.
  8. Mills JL, Harley E, Reed G, Berendes HW. Are spermicides teratogenic? JAMA 1982; 248:2148-2151.
  9. Mills JL, Fishl A, Knopp R, Ober C, Jovanovic L, Polk BF, and the DIEP. Malformations in infants of diabetic mothers: Problems in study design. Prev Med 1983; 12:274-286.
  10. Mills JL, Harley EE, Moessinger A. Standards for measuring umbilical cord length. Placenta 1983; 4:423-425.
  11. Breskin M, Worthington-Roberts B, Knopp R, Brown Z, Plovie B, Mottet N, Mills JL. First trimester serum zinc concentrations in human pregnancy. Am J Clin Nutr 1983; 38:943-953.
  12. Diabetes Research Program - National Institutes of Health. Summary of a Workshop on Immunosuppression in the Management of Type I Diabetes Mellitus (IDDM). N Engl J Med 1983; 309:1199-1200.
  13. Jovanovic L, Mills JL, Peterson C. Anti-insulin antibody titers do not influence control or insulin requirements in early pregnancy. Diabetes Care 1984; 7:68-71.
  14. Rhoads GG, Mills JL. The role of the case-control study in evaluating health interventions: Vitamin supplementation and neural tube defects. Am J Epidemiol 1984; 120:803-808.
  15. Mills JL, Jefferys J, Stolley P. Effects of occupational exposure to estrogen and progestogens. J Occup Med 1984; 26:269-272.
  16. Mills JL, Graubard BI, Harley EE, Rhoads GG, Berendes HW. Maternal alcohol consumption and birth weight: How much drinking during pregnancy is safe? JAMA 1984; 252:1875-1879.
  17. Mills JL, Reed G, Nugent RP, Harley EE, Berendes HW. Are there adverse effects of periconceptional spermicide use? Fertil Steril 1985; 43:442-446.
  18. Castracane VD, Jovanovic L, Mills JL. Effect of normoglycemia before conception on early pregnancy hormone profiles. Diabetes Care 1985; 8:473-476.
  19. Klebanoff MA, Mills JL, Berendes HW. Mother's birth weight as a predictor of macrosomia. Am J Obstet Gynecol 1985; 153:253-257.
  20. Klebanoff MA, Mills JL. Is vomiting during pregnancy teratogenic? Brit Med J 1986; 292:724-726.
  21. Marx S, Vinik A, Santen R, Floyd J, Mills JL, Green J. Multiple endocrine neoplasia type I: Assessment of laboratory tests to screen for the gene in a large kindred. Medicine1986; 65:226-241.
  22. Mills JL, Shiono PH, Shapiro L, Crawford P, Rhoads GG. Early growth predicts timing of puberty in boys: Results of a 14 year nutrition and growth study. J Pediatr 1986; 109:543-547.
  23. Rhoads GG, Mills JL. Can vitamin supplements prevent neural tube defects? Current evidence and ongoing investigations. Clin Obstet Gynecol 1986; 29:569-579.
  24. Mills JL. Malformations in infants of diabetic mothers. In: John Sever, Robert Brent (eds.). Teratogen Update. Alan R. Liss, New York, 1986, pp. 165-176.
  25. Freni-Titulaer LW, Cordero JF, Haddock L, Lebron G, Martinez R, Mills JL. Premature thelarche in Puerto Rico: A search for environmental factors. Am J Dis Child 1986; 140:1263-1267.
  26. Moessinger AC, Mills JL, Harley EE, Ramakrishnanm R, Berendes HW, Blanc WA. Umbilical cord length in Down's syndrome. Am J Dis Child 1986; 140:1276-1277.
  27. Mills JL, Alexander D. Teratogens and "litogens". N Engl J Med 1986; 315:1234-1236.
  28. Mills JL, Graubard BI, Klebanoff MA. An association of placenta praevia and sex ratio at birth. Brit Med J 1987; 294:544.
  29. Mills JL, Graubard BI. Is moderate drinking during pregnancy associated with an increased risk for malformations? Pediatr 1987; 80:309-314.
  30. Jovanovic L, Singh M, Saxena BB, Mills JL, Tulchinsky D, Holmes LB, Simpson JL, Metzger BE, LaBarbera A, Aarons JH, Van Allen MI, the NICHD-DIEP Study Group. Verification of early pregnancy tests in a multicentered trial. Proc Soc Exp Biol Med 1987; 184:201-205.
  31. Simpson JL, Mills JL, Holmes LB, Ober CL, Aarons JH, Jovanovic L, Knopp RH, the DIEP Study Group. Low fetal loss rates following ultrasound-proved viability in early pregnancy. JAMA 1987; 258:2555-2557.
  32. Sweeney AM, Meyer MR, Aarons JH, Mills JL, LaPorte RE. Evaluation of methods for the prospective identification of early fetal losses in environmental epidemiology studies. Am J Epidemiol 1988; 127:843-850.
  33. Mills JL, Knopp RH, Simpson JL, Jovanovic-Peterson L, Metzger BE, Holmes LB, Aarons JH, Brown Z, Reed GF, Bieber FR, Van Allen M, Holzman I, Ober C, Peterson CM, Withiam MJ, Duckles A, Mueller-Heubach E, Polk BF, the NICHD-DIEP Study. Lack of relation of increased malformation rates in infants of diabetic mothers to glycemic control during organogenesis. N Engl J Med 1988; 318:671-676.
  34. Mills JL, Simpson JL, Driscoll SG, Jovanovic-Peterson L, Van Allen M, Aarons JH, Peterson CM, Withiam-Wilson M, Brown Z, Ober C, Harley E, Macpherson TA, Duckles A, Mueller-Heubach E, the NICHD-DIEP Study. Incidence of spontaneous abortion among normal women and insulin-dependent diabetic women whose pregnancies were identified within 21 days of conception. N Engl J Med 1988; 319:1617-1623.
  35. Braunstein GD, Mills JL, Reed GD, Jovanovic LC, Holmes LB, Aarons JH, Simpson JL, the NICHD-DIEP Study Group. Comparison of serum placental protein hormone levels in diabetic and normal pregnancy. J Clin Endocrin Metab 1989; 68:3-8.
  36. Simpson JL, Mills JL, Morey A, Metzger BE, Knopp RH, Holmes LB, Jovanovic L, Aarons JH, Brown Z, Van Allen M, Elias S, NICHD-DIEP Study Group. Drug ingestion during pregnancy: infrequent exposure in a contemporary United States sample. Am J Perinatol 1989; 6:244-251.
  37. Mills JL, Rhoads GG, Simpson JL, Cunningham GC, Conley MR, Lassman MR, Walden ME, Depp OR, Hoffman HJ, and the NICHD-Neural Tube Defects Study Group. The absence of a relation between the periconceptional use of vitamins and neural-tube defects. N Engl J Med 1989; 321:430-435.
  38. Morin NC, Wirth FH, Johnson DH, Frank LM, Pressburg HJ, Van De Water VL, Chee EM, Mills JL. Congenital malformations and psychosocial development in children conceived by in vitro fertilization. J Pediatr 1989; 115:222-227.
  39. Sweeney AM, Meyer MR, Mills JL, Aarons JH, LaPorte RE. Evaluation of recruitment strategies for prospective studies of spontaneous abortion. J Occupat Med 1989; 31:980-985.
  40. Mills JL, Simpson JL, Rhoads GG, Graubard BI, Hoffman HJ, Conley MR, Lassman M, Cunningham G. Risk of neural tube defects in relation to maternal fertility and fertility drug use. The Lancet 1990; 336:103-104.
  41. Mills JL, Fradkin J, Schonberger L, Gunn W, Thomson RA, Piper J, Wysowski D, Brown P. Status report on the U.S. human growth hormone recipient follow-up study. Hormone Res 1990; 33:116-120.
  42. Jovanovic-Peterson L, Peterson CM, Reed GF, Metzger BE, Mills JL, Knopp RH, Aarons JH, and the NICHD-DIEP Study. Maternal postprandial glucose levels and infant birth weight: The Diabetes in Early Pregnancy Study. Am J Obstet Gynecol 1991; 164:103-111.
  43. Fradkin JL, Schonberger LB, Mills JL, Gunn WJ, Piper JM, Wysowski DK, Thomson R, Durako S, Brown P. Creutzfeldt-Jakob disease in pituitary growth hormone recipients in the United States. JAMA 1991; 265:880-884.
  44. Simpson JL, Mills JL, Rhoads GG, Cunningham GC, Hoffman HJ, Conley MR. Vitamins, folic acid and neural tube defects: Comments on investigations in the United States. Prenatal Diagnosis (Special issue relating to International Congress on Early Fetal Diagnosis)1991; 11:641-648.
  45. Mills JL, Klebanoff MA, Graubard BI, Carey JC, Berendes HW. Barrier contraceptive methods and preeclampsia. JAMA 1991; 265:70-73.
  46. Simpson JL, Mills JL, Rhoads GG, Cunningham GC, Conley MR, Hoffman HJ. Genetic heterogeneity in neural tube defects. Ann Génét 1991; 34:279-286.
  47. Peterson CM, Jovanovic-Peterson L, Mills JL, Conley MR, Knopp RH, Reed GF, Aarons JH, Holmes LB, Brown Z, Van Allen M, Schmeltz R, Metzger BE, the NICHD-Diabetes in Early Pregnancy Study. The Diabetes in Early Pregnancy Study: Changes in cholesterol, triglycerides, body weight, and blood pressure. Am J Obstet Gynecol 1992; 166:513-518.
  48. Brown ZA, Mills JL, Metzger BE, Knopp RH, Simpson JL, Jovanovic-Peterson L, Scheer K, Van Allen MI, Aarons JH, Reed GF, and the National Institute of Child Health and Human Development Diabetes in Early Pregnancy Study. Early sonographic evaluation for fetal growth delay and congenital malformations in pregnancies complicated by insulin-requiring diabetes mellitus. Diabetes Care 1992; 15:613-619.
  49. Mills JL, Tuomilehto J, Yu KF, Colman N, Blaner WS, Koskela P, Rundle WE, Forman M, Toivanen L, Rhoads GG. Maternal vitamin levels during pregnancies producing infants with neural tube defects. J Pediatr 1992; 120:863-871.
  50. Mills JL, Raymond E. Effects of recent research on recommendations for periconceptional folate supplement use. Ann N Y Acad Sci `993; 678:137-145.
  51. Mills JL, Holmes L, Aarons JH, Simpson JL, Brown ZA, Jovanovic-Peterson, LG, Conley MR, Graubard BI, Knopp R, Metzger BE. Moderate caffeine use and the risk of spontaneous abortion and intrauterine growth retardation. JAMA 1993; 269:593-597.
  52. Klebanoff MA, Read JS, Mills JL, Shiono PH. The risk of childhood cancer after neonatal exposure to vitamin K. N Engl J Med 1993; 329:905-908.
  53. Jacobson JM, Colman N, Ostrow NA, Simson RW, Tomesch D, Marlin L, Rao M, Mills J, Clemen J, Prince AM. Passive immunotherapy in the treatment of advanced HIV infection. J Infect Dis 1993; 168:298-305.
  54. Mills JL, Simpson JL. Prospects for prevention of neural tube defects by vitamin supplementation. Current Opinion in Neurology and Neurosurgery 1993; 6:554-558.
  55. Robins LN, Mills JL, Krulewitch C, Herman AA. Effects of in utero exposure to street drugs. Amer J Publ Hlth 1993; Supplement to vol. 83:1-32.
  56. Raymond E, Mills JL. Placental abruption: Maternal risk factors and associated fetal conditions. Acta Obstet Gynecol Scand 1993; 72:633-639.
  57. Mills JL. Data torturing. N Engl J Med 1993; 329:1196-1199.
  58. Fradkin JE, Mills JL, Schonberger LB, Wysowski DK, Thomson R, Durako SJ, Robison LL. Risk of leukemia after treatment with pituitary growth hormone. JAMA 1993; 270:2829-2832.
  59. Waller KD, Mills JL, Simpson JL, Cunningham GC, Conley MR, Lassman MR, Rhoads GG. Are obese women at risk for producing malformed offspring? Am J Obstet Gynecol 1994; 170:541-548.
  60. Shu XO, Jin F, Linet MS, Zheng W, Clemens J, Mills J, Gao YT. Diagnostic x-ray and ultrasound exposure and risk of childhood cancer. Brit J Cancer 1994; 70:531-536.
  61. Haupt R, Fears TR, Robison LL, Mills JL, Nicholson HS, Zeltzer LK, Meadows AT, Byrne J. Educational attainment in long-term survivors of childhood acute lymphoblastic leukemia. JAMA 1994; 272:1427-1432.
  62. Mills JL, McPartin JM, Kirke PN, Lee YJ, Conley MR, Weir DG, Scott JM. Homocysteine metabolism in pregnancies complicated by neural-tube defects. Lancet 1995; 345:149-151.
  63. Shu XO, Hatch MC, Mills JL, Clemens JD, Susser M. Maternal smoking, alcohol drinking, caffeine consumption and fetal growth: Results from a prospective study. Epidemiol 1995; 6:115-120.
  64. Chew EY, Mills JL, Metzger BE, Remaley NA, Jovanovic-Peterson L, Knopp RH, Conley MR, Rand L, Simpson JL, Holmes LB, Aarons JH, and the NICHD Diabetes in Early Pregnancy Study. Metabolic control and progression of retinopathy: The Diabetes In Early Pregnancy Study. Diabetes Care 1995; 18:631-637.
  65. Mills JL, Conley MR. Periconceptional vitamin supplementation to prevent neural tube defects: How can we do it? Eur J Obstet Gynecol Reprod Biol 1995; 61:49-55.
  66. Mills JL, Scott JM, Kirke PN, McPartlin JM, Conley MR, Weir DG, Molloy AM, Lee YJ. Homocysteine and neural tube defects. J Nutr 1996; 126:756S-760S.
  67. Simpson JL, Mills JL, Kim H, Holmes LB, Lee J, Metzger B, Knopp R, Jovanovic-Peterson L, Aarons J, Conley M. Infectious processes: an infrequent cause of first trimester spontaneous abortions. Hum Reprod 1996; 11:668-72.
  68. Whitehead AS, Gallagher P, Mills JL, Kirke PN, Burke H, Molloy AM, Weir DG, Shields DC, Scott JM. A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects. Q J Med 1995; 88:763-766.
  69. Kenney LB, Nicholson HS, Brasseux C, Mills JL, Robison LL, Zeltzer LK, Meadows AT, Reaman GH, Byrne J. Birth defects in offspring of adult survivors of childhood acute lymphoblastic leukemia: a Children=s Cancer Group/National Institutes of Health Report. Cancer 1996; 78:169-176.
  70. Simpson JL, Carson SA, Mills JL, Conley MR, Aarons J, Holmes LB, Jovanovic-Peterson L, Knopp R, Metzger B. Prospective study showing that antisperm antibodies are not associated with pregnancy losses. Fertil Steril 1996; 66:36-42.
  71. Mills JL, Conley MR. Folic acid to prevent neural tube defects: scientific advances and public health issues. Curr Opin Obstet Gynecol 1996; 8:394-397.
  72. Zeltzer LK, Chen E, Weiss R, Guo MD, Robinson LL, Meadows AT, Mills JL, Nicholson HS, Byrne J. Comparison of psychologic outcome in adult survivors of childhood acute lymphoblastic leukemia versus sibling controls: a Children's Cancer Group and National Institutes of Health study. J Clin Oncol 1997; 15:547-556.
  73. Ramsbottom D, Scott JM, Molloy A, Weir DG, Kirke PN, Mills JL,
    Gallagher PM, Whitehead AS. Are common mutations of cystathionine beta-synthase involved in the aetiology of neural tube defects? Clin Genet 1997; 51:39-42.
  74. Mills JL, Simpson JL, Cunningham GC, Conley MR, Rhoads GG. Vitamin A and birth defects. Am J Obstet Gynecol, 177:31-36, 1997.
  75. Mills JL, Fears TR, Robison LL, Nicholson HS, Sklar CA, Byrne J. Menarche in a cohort of 188 long-term survivors of acute lymphoblastic leukemia. J Pediatr 1997; 131:598-602.
  76. Kirke PN, Mills JL, Scott JM. Homocysteine metabolism in pregnancies complicated by neural tube defects. J Nutr 1997; 13:994-57.
  77. Cnattingius S, Mills JL, Yuen J, Eriksson O, Salonen-Ross H. The paradoxical effect of smoking in preeclamptic pregnancies: smoking reduces the incidence but increases the rates of perinatal mortality, abruptio placentae, and intrauterine growth restriction. Am J Obstet Gynecol 1997; 177:156-61.
  78. Molloy AM, Daly S, Mills JL, Kirke PN, Whitehead AS, Ramsbottom D, Conley MR, Weir DG, Scott JM. Thermolabile variant of 5,10 methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations. Lancet 1997; 349:1591-93.
  79. Molloy AM, Mills JL, Kirke PN, Ramsbotton D, McPartlin JM, Burke H, Conley M, Whitehead AS, Weir DG, Scott JM. Low blood folates in NTD pregnancies are only partly explained by thermolabile 5,10-methylenetetrahydrofolate reductase: Low folate status alone may be the critical factor. Am J Med Genet 1998; 78:155-159.
  80. Daly S, Mills JL, Molloy AM, Conley M, Lee YJ, Kirke PN, Weir DG, Scott JM. Minimum effective dose of folic acid for food fortification to prevent neural-tube defects. Lancet 1997; 350:1666-69.
  81. Simpson JL, Carson SA, Chesney C, Conley MR, Metzger B, Aarons J, Holmes JB, Jovanovic-Peterson L, Knopp R, Mills JL. Lack of association between anti-phospholipid antibodies and first trimester spontaneous abortion: prospective study of pregnancies detected within 21 days of conception. Fertil Steril 1998; 69:814-20.
  82. Miller RK, Hendrickx AG, Mills JL, Hummler H, Wiegand U. Periconceptional vitamin A use: how much is teratogenic? Reprod Toxicol 1998; 12:75-88.
  83. Mills JL, Jovanovic L, Knopp R, Aarons J, Conley M, Park E, Lee YJ, Holmes L, Simpson JL, Metzger B. Physiological reduction in fasting plasma glucose concentration in the first trimester of normal pregnancy: The Diabetes in Early Pregnancy Study. Metabolism 1998; 47:1140-44.
  84. Vargas FR, Roessler E, Gaudenz K, Belloni E, Whitehead AS, Kirke PN, Mills JL, Hooper G, Stevenson RE, Cordeiro I, Correia P, Felix T, Gereige R, Cunningham ML, Canun S, Antonarakis SE, Strachan T, Tsui LC, Scherer SW, Muenke M. Analysis of the human Sonic Hedgehog coding and promoter regions in sacral agenesis, triphalangeal thumb, and mirror polydactyly. Hum Genet 1998; 102:387-392.
  85. Molloy AM, Mills JL, Kirke PN, Whitehead AS, Weir DG, Scott JM. Whole-blood folate values in subjects with different methylenetetrahydrofolate reductase genotypes: Differences between the radioassay and microbiological assays. Clin Chem 1998; 44:186-188.
  86. Jovanovic L, Metzger BE, Knopp RH, Conley MR, Park E, Lee YJ, Simpson JL, Holmes L, Aarons JH, Mills JL. The Diabetes in Early Pregnancy Study: Beta-hydroxybutyrate levels in type I diabetic pregnancy compared with normal pregnancy. Diabetes Care 1998; 21:1978-84.
  87. Tao ML, Guo MD, Weiss R, Byrne J, Mills JL, Robison LL, Zeltzer LK. Smoking in adult survivors of childhood acute lymphoblastic leukemia. J Natl Cancer Inst 1998; 90:219-25.
  88. Shields DC, Kirke PN, Mills JL, Ramsbottom D, Molloy AM, Burke H, Weir DG, Scott JM, Whitehead AS. The >thermolabile= variant of methylenetetrahydrofolate reductase and neural tube defects: an evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother. Am J Hum Genet 1999; 164:1045-1055.
  89. Chen E, Zeltzer LK, Bentler PM, Byrne J, Nicholson HS, Meadows AT, Mills JL, Haupt R, Fears TR, Robison, LL. Pathways linking treatment intensity and psychosocial outcomes among adult survivors of childhood leukemia. J Health Psychol 1998; 3:23-38.
  90. Mills JL, DerSimonian R, Raymond E, Morrow JD, Roberts II LJ, Clemens JD, Hauth JC, Catalano P, Sibai B, Curet LB, Levine RJ. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia. JAMA 1999; 282:356-362.
  91. Mills JL, Kirke PN, Molloy AM, Burke H, Conley MR, Lee YJ, Mayne PD, Weir DG, Scott JM. Methylenetetrahydrofolate reductase thermolabile variant and oral clefts. Am J Med Genet 1999; 86:71-74.
  92. Brody LC, Baker PJ, Chines PS, Musick A, Molloy AM, Swanson DA, Kirke PN, Ghoush S, Scott JM, Mills JL. Methionine synthase: high resolution mapping of the human gene and evaluation as a candidate locus for neural tube defects. Mol Genet Metabol 1999; 67: 324-333.
  93. Whitehead AS, Molloy AM, Ramsbottom, D, Weir DG, Kirke PN, Mills, JL, Gallagher PM, Scott JM. Gene-gene interactions and neural tube defects. Clin Genet 1999; 55:133-4.
  94. Daly SF, Molloy AM, Mills JL, Lee YJ, Conley M, Kirke PN, Weir DG, Scott JM. The influence of 5,10 methylenetetrahydrofolate reductase genotypes on enzyme activity in placental tissue. Br J Obstet Gynaecol 1999; 106:1214-8.
  95. Molloy AM, Mills JL, Kirke PN, Weir DG, Scott JM. Folate status and neural tube defects. Biofactors 1999; 10:291-4.
  96. Shields DC, Ramsbottom D, Donoghue C, Pinjon E, Kirke PN, Molloy AM, Edwards YH, Mills JL, Mynett-Johnson L, Weir DG, Scott JM, Whitehead AS. Association between historically high frequencies of neural tube defects and the human T homologue of mouse T (Brachyury). Am J Med Genet 2000; 92: 206-11.
  97. Mills JL. Fortification of foods with folic acid: how much is enough? N Engl J Med 2000; 342: 1442-5.
  98. Jovanovic L, Knopp RH, Brown Z, Conley MR, Park E, Mills JL, Metzger BE, Aarons JH, Holmes LB, Simpson JL. Declining insulin requirements in the late first trimester of diabetic pregnancy. Diabetes Care 2001; 24: 1130-6.
  99. Feinleib M, Beresford SAA, Bowman BA, Mills JL, Rader JI, Selhub J, Yetley EA. Folate fortification for the prevention of birth defects: Case study. Am Journal Epidemiol 2001; 154: S 60-S69, supplement.
  100. O'Leary VB, Parle-McDermott A, Molloy AM, Kirke PN, Johnson Z, Conley M, Scott JM, Mills JL. MTRR and MTHFR polymorphism: Link to Down syndrome? Am J Med Genet 2002; 107: 151-155.
  101. Molloy AM, Mills JL, McPartlin J, Kirke PN, Scott JM, Daly S. Maternal and fetal plasma homocysteine concentrations at birth: The influence of folate, vitamin B12, and the 5,10 methylenetetrahydrofolate reductase 677 C->T variant. Am J Obstet Gynecol 2002; 186: 499-503.
  102. Daly S, Mills JL, Molloy AM, Conley M, McPartlin J, Lee YJ, Young PB, Kirke PN, Weir DG, Scott JM. Low dose folic acid lowers plasma homocysteine levels in women of child bearing age: A double blind, randomized placebo controlled trial. Q J Med 2002; 95:733-40.
  103. George L, Mills JL, Johansson ALV, Nordmark A, Olander B, Granath F, Cnattingius S. Plasma folate levels and risk of spontaneous abortion. JAMA 2002; 288: 1867-73.
  104. Birth Defects Research group (in alphabetical order): Brody LC, Conley M, Cox C, Kirke PN, McKeever MP, Mills JL, Molloy AM, O'Leary VB, Parle-McDermott A, Scott JM, Swanson DA. A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate-cyclohydrolase, formyltetrahydrofolate synthetase (MTHFD1) is a maternal genetic risk factor for neural tube defects. Am J Hum Genet 2002; 71: 1207-15.
  105. Mills JL, Von Kohorn I, Conley MR, Zeller JA, Cox C, Williamson RE, Dufour DR. Low vitamin B12 levels presenting without anemia: the effect of folic acid fortification of grain. Amer J Clin Nutr 2003; 77: 1474-7.
  106. Parle-McDermott A, Mills JL, Kirke PN, O'Leary PB, Swanson DA, Pangilanin F, Conley M, Molloy AM, Cox C, Scott JM, Brody LC. Analysis of the MTHFR 1298 A->C and 677C->T polymorphisms as risk factors for neural tube defects J Hum Genet 2003; 48: 190-3.
  107. Mills JL, England L, Granath F, Cnattinguis S. Cigarette smoking and male:female sex ratio. Fertil Steril 2003; 79:1243-5.
  108. O'Leary VB, Mills JL, Kirke PN, Parle-McDermott AP, Swanson DA, Weiler A, Pangilinan F, Conley M, Molloy AM, Lynch M, Cox C, Scott JM, Brody LC. Analysis of the human folate receptor beta gene for an association with neural tube defects. Mol Genet Metabol 2003; 79: 129-33.
  109. England LJ, Levine RJ, Mills JL, Klebanoff MA, Yu KF, Cnattingius S. Adverse pregnancy outcomes in snuff users. Am J Obstet Gynecol 2003; 189: 939-943.
  110. Parle-Mc Dermott A, Mc Manus EJ, Mills JL, O'Leary VB, Pangilinan F, Cox C, Weiler A, Molloy AM, Conley M, Watson D, Scott JM, Brody LC, Kirke PN Members of the Birth Defects Research Group. Polymorphisms within the vitamin B12 dependent methylmalonyl-coA mutase are not risk factors for neural tube defects. Mol Genet Metabol 2003; 80: 463-468.
  111. Glover DA, Byrne J, Mills JL, Robison LL, Nicholson HS, Meadows A, Zeltzer LK. Impact of central nervous system treatment on mood in adult survivors of childhood leukemia: A report from the Children's Cancer Group J Clin Oncol 2003; 21: 4395-4401.
  112. Byrne J, Fears TR, Mills JL, Zeltzer LK, Sklar C, Nicholson HS, Haupt R, Reaman GH, Meadows AT, Robison LL. Fertility in women treated with cranial radiotherapy for childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2004; 42:589-597.
  113. Mills JL, Schonberger LB, Wysowski DK, Brown P, Durako S, Cox C, Kong F, Fradkin JE. Long-term mortality in the United States cohort of pituitary-derived growth hormone recipients. J Pediatr 2004; 144:430-436.
  114. Avaria M, Mills JL, Kleinsteuber K, Aros S, Conley MR, Cox C, Klebanoff M, Cassorla F. Peripheral nerve conduction abnormalities in children exposed to alcohol in utero. J Pediatr 2004; 144:338-343.
  115. Kirke PN, Mills JL, Molloy AM, Brody LC, O'Leary VB, Daly L, Murray S, Conley M, Mayne P, Smith O, Scott JM. A single polymorphism (MTHFR C677T) puts half of the population at increased risk of neural tube defects: case-control study. Brit Med J 2004; 328:1535-6.
  116. Seitzman RL, Glover DA, Meadows AT, Mills JL, Nicholson HS, Robison LL, Byrne J, Zeltzer LK. Self-concept in adult survivors of childhood acute lymphoblastic leukemia: A Cooperative Children's Cancer Group and National Institutes of Health Study. Pediatr Blood Cancer 2004; 42:230-240.
  117. Byrne J, Fears TR, Mills JL, Zeltzer LK, Sklar C, Meadows AT, Reaman GH, Robison LL. Fertility of long-term male survivors of acute lymphoblastic leukemia diagnosed during childhood Pediatr Blood Cancer 2004; 42: 364-72.
  118. Parle-McDermott A, Mills JL, Kirke PN, Cox C, Signore CC, Kirke S, Molloy AM, O'Leary VB, Pangilinan FJ, O'Herlihy C, Brody LC, Scott JM. The MTHFD1 R653Q polymorphism is a maternal genetic risk factor for severe abruptio placentae. Amer J Med Gen A 2004; 132: 365-8.
  119. Rao MR, Brenner RA, Schisterman EF, Vik T, Mills JL. Impaired long term cognitive development in children with persistent crying. Arch Dis Child 2004; 89:989-92.
  120. Mills JL, Signore C. Birth defect rates before and after food fortification with folic acid.. Birth Defects Res A Clin Mol Teratol 2004; 70: 844.
  121. Swanson DA, Pangilinan F, Mills JL, Kirke PN, Conley M, Weiler A, Frey T, Parle-McDermott A, O'leary VB, Seltzer RR, Moynihan KA, Molloy AM, Burke H, Scott JM, Brody LC. Evaluation of transcobalamin II polymorphisms as neural tube defect risk factors in an Irish population. Birth Defects Res A Clin Mol Teratol 2005; 73:239-44.
  122. Signore C, Mills JL, Cox C, Trumble AC. Effects of folic acid fortification on twin gestation rates. Obstet Gynecol 2005; 105:757-62.
  123. Jovanovic L, Knopp RH, Kim H, Cefalu WT, Zhu XD, Lee YJ, Simpson JL, Mills JL. Elevated pregnancy losses at high and low extremes of maternal glucose in early normal and diabetic pregnancy: Evidence for a protective adaptation in diabetes. Diabetes Care 2005; 28:1113-7.
  124. O'Leary VB, Mills JL, Pangilinan F, Kirke PN, Cox C, Conley M, Weiler A, Peng K, Shane B, Scott JM, Parle-McDermott A, Molloy AM, Brody LC Members of the Birth Defects Research Group. Analysis of methionine synthase reductase polymorphisms for neural tube defect association. Mol Genet Metab 2005; 85:220-7.
  125. Molloy AM, Mills JL, Cox C, Daly SF, Conley M, Brody LC, Kirke PN, Scott JM, Ueland PM. Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery. Am J Clin Nutr 2005; 82:836-842.
  126. Parle-McDermott A, Pangilinan F, Mills JL, Signore CC, Molloy AM, Cotter A,Conley M, Cox C, Kirke PN, Scott JM, Brody LC. A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss. Mol Hum Reprod 2005; 11:477-480.
  127. O'Leary VB, Mills JL, Parle-McDermott A, Pangilinan F, Molloy AM, Cox C, Weiler A, Conley M, Kirke PN, Scott JM, Brody LC; Birth Defects Research Group. Screening for new MTHFR polymorphisms and NTD risk. Am J Med Genet A 2005; 138:99-106.
  128. Mills JL, Druschel CM, Pangilinan F, Pass K, Cox C, Seltzer RR, Conley MR, Brody LC. Folate-related genes and omphalocele. Am J Med Genet A 2005; 136:8-11.
  129. O'Leary VB, Pangilinan F, Cox C, Parle-McDermott A, Conley M, Molloy AM, Kirke PN, Mills JL, Brody LC, Scott JM; Members of the Birth Defects Research Group. Reduced folate carrier polymorphisms and neural tube defect risk. Mol Genet Metab 2006; 87:364-9.
  130. Aros S, Mills JL, Torres C, Henriquez C, Fuentes A, Capurro T, Mena M, Conley M, Cox C, Signore C, Klebanoff M, Cassorla F. Prospective identification of pregnant women drinking four or more standard drinks (> or = 48 g) of alcohol per day. Subst Use Misuse 2006; 41:183-97.
  131. Parle-McDermott A, Kirke PN, Mills JL, Molloy AM, Cox C, O'leary VB, Pangilinan F, Conley M, Cleary L, Brody LC, Scott JM. Confirmation of the R653Q polymorphism of the trifunctional C1-synthase enzyme as a maternal risk for neural tube defects in the Irish population. Eur J Hum Genet 2006; 14:768-72.
  132. Signore C, Mills JL, Qian C, Yu K, Lam C, Epstein FH, Karumanchi SA, Levine RJ. Circulating angiogenic factors and placental abruption. Obstet Gynecol 2006; 108:338-44.
  133. Parle-McDermott A, Mills JL, Molloy AM, Carroll N, Kirke PN, Cox C, Conley MR, Pangilinan FJ, Brody LC, Scott JM. The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels. Mol Genet Metab 2006; 88:290-4.
  134. Parle-McDermott A, Pangilinan F, Mills JL, Kirke PN, Gibney ER, Troendle J, O'Leary VB, Molloy AM, Conley M, Scott JM, Brody LC. The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population. Am J Med Genet A 2007; 143:1174-80.
  135. Mills JL, Hediger ML, Molloy CA, Chrousos GP, Manning-Courtney P, Yu KF, Brasington M, England LJ.
    Elevated levels of growth-related hormones in autism and autism spectrum disorder. Clin Endocrinol (Oxf) 2007; 67:230-7.
  136. Hediger ML, England LJ, Molloy CA, Yu KF, Manning-Courtney P, Mills JL. Reduced bone cortical thickness in boys with autism or autism spectrum disorder. J Autism Dev Disord 2008; 38:848-856
  137. Signore C, Ueland PM, Troendle J, Mills JL. Choline concentrations in human maternal and cord blood and
    intelligence at 5 y of age. Am J Clin Nutr. 2008; 87:896-902.
  138. Mills JL, Molloy AM, Parle-McDermott A, Troendle JF, Brody LC, Conley MR, Cox C, Pangilinan F, Orr DJA, Earley M, McKiernan E, Lynn EC, Doyle A, Scott JM, KirkePN. Folate-related Gene Polymorphisms as Risk Factors for Cleft Lip and Cleft Palate. Birth Defects Res A Clin Mol Teratol. 2008;82: 636-643.
  139. Pangilinan F, Geiler K, Dolle J, Troendle J, Swanson DA, Molloy AM, Sutton M, Conley M, Kirke PN, Scott JM, Mills JL and Brody LC. Construction of a high resolution linkage disequilibrium map to evaluate common genetic variation in TP53 and neural tube defect risk in an Irish population. Am J Med Genet A 2008; 146A: 2617-2625.
  140. Signore C, Aros S, Morrow JD, Troendle J, Conley MR, Flanigan EY, Cassorla F, Mills JL. Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking greater than or equal to 48 grams of alcohol per day. Alcohol Clin Exp Res 2008; 32: 1893-1898.
  141. Signore C, Mills JL, Qian C, Yu KF, Rana S, Karumanchi A, Levine RJ. Circulating soluble endoglin and placental abruption. Prenat Diagn. 2008; 28:852-858.
  142. Flanigan EY, Aros S, Bueno MF, Conley M, Troendle JF, Cassorla F, Mills JL. Eye malformations in children with heavy alcohol exposure in utero. J Pediatr. 2008;153:391-395.
  143. Molloy AM, Kirke PN, Troendle JF, Burke H, Sutton M, Brody LC, Scott JM, Mills JL. Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic acid fortification. Pediatr 2009.123:917-23.
  144. Mitchell A, Pangilinan P, VanderMeer J, Molloy AM, Troendle J, Conley M, Kirke PN, Scott JM, Brody LC, Mills JL. Uncoupling protein 2 polymorphisms as risk factors for neural tube defects. Birth Defects Res A Clin Mol Teratol. 2009 85: 156-60.
  145. Carroll N, Pangilinan F, Molloy AM, Troendle J, Mills JL, Kirke PN, Brody LC, Scott JM, Parle-McDermott A. Analysis of the MTHFD1 promoter and risk of neural tube defects. Hum Genet 2009. 129: 247-56.
  146. Molloy AM, Brody LC, Mills JL, Scott JM, Kirke PN. The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human NTD. Birth Defects Res A Clin Mol Teratol 2009. 85:285-94.
  147. Troendle JF, Yu KF, Mills JL. Testing for genetic association with constrained models using triads. Ann Hum Genet. 2009 73:225-30.
  148. Molloy AM, Quadros EV, Sequeira JM, Troendle JF, Scott JM, Kirke PN, Mills JL. Lack of association between folate-receptor autoantibodies and neural-tube defects. N Engl J Med. 2009. 361:152-60.
  149. Parle-McDermott A, Pangilinan F, O'Brien KK, Mills JL, Magee AM, Troendle J, Sutton M, Scott JM, Kirke PN, Molloy AM, Brody LC. A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency. Hum Mutat. 2009. 30:1650-6.
  150. Moslehi R, Signore C, Tamura D, Mills JL, Digiovanna JJ, Tucker MA, Troendle J, Ueda T, Boyle J, Khan SG, Oh KS, Goldstein AM, Kraemer KH. Adverse effects of trichothiodystrophy DNA repair and transcription gene disorder on human fetal development. Clin Genet. 2010. 77:365-73.
  151. Carter TC, Molloy AM, Pangilinan F, Troendle JF, Kirke PN, Conley MR, Orr DJ, Earley M, McKiernan E, Lynn EC, Doyle A, Scott JM, Brody LC, Mills JL. Testing reported associations of genetic risk factors for oral clefts in a large Irish study population. Birth Defects Res A Clin Mol Teratol. 2010. 88: 84-93.
  152. Bloom MS, Houston AS, Mills JL, Molloy CA, Hediger ML. . Finger bone immaturity and 2D:4D ratio measurement error in the assessment of the hyperandrogenic hypothesis for the etiology of autism spectrum disorders. Physiol Behav. 2010. 100:221-4.
  153. Mills JL, Troendle J, Conley MR, Carter T, Druschel CM. Maternal obesity and congenital heart defects: a population-based study. Am J Clin Nutr. 2010 Jun;91(6):1543-9.
  154. Beaty TH, Murray JC, Marazita ML, Munger RG, Ruczinski I, Hetmanski JB, Liang KY, Wu T, Murray T, Fallin MD, Redett RA, Raymond G, Schwender H, Jin SC, Cooper ME, Dunnwald M, Mansilla MA, Leslie E, Bullard S, Lidral AC, Moreno LM, Menezes R, Vieira AR, Petrin A, Wilcox AJ, Lie RT, Jabs EW, Wu-Chou YH, Chen PK, Wang H, Ye X, Huang S, Yeow V, Chong SS, Jee SH, Shi B, Christensen K, Melbye M, Doheny KF, Pugh EW, Ling H, Castilla EE, Czeizel AE, Ma L, Field LL, Brody L, Pangilinan F, Mills JL, Molloy AM, Kirke PN, Scott JM, Arcos-Burgos M, Scott AF. A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. Nat Genet. 2010.42:525-9.
  155. Molloy CA, Kalkwarf HJ, Manning-Courtney P, Mills JL, Hediger ML. Plasma 25 (OH)D concentration in children with autism spectrum disorder. Dev Med Child Neurol. 2010;52:969-971
  156. Obican SG, Finnell RH, Mills JL, Shaw GM, Scialli AR. Folic acid in early pregnancy: a public health success story. FASEB J. 2010
  157. Pangilinan F, Mitchell A, VanderMeer J, Molloy AM, Troendle J, Conley M, Kirke PN, Sutton M, Sequeira JM, Quadros EV, Scott JM, Mills JL, Brody LC. Transcobalamin II receptor polymorphisms are associated with increased risk for neural tube defects. J Med Genet. 2010;47:677-85.
  158. Bailey RL, Mills JL, Yetley EA, Gahche JJ, Pfeiffer CM, Dwyer JT, Dodd KW, Sempos CT, Betz JM, Picciano MF. Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged > or = 60 years in the United States. Am J Clin Nutr. 2010;92:383-9.
  159. Troendle JF, Mills JL. Correction for multiplicity in genetic association studies of triads: the permutation TDT. Ann Hum Genet. 2011 75(2):284-91.
  160. Carter TC, Pangilinan F, Troendle JF, Molloy AM, Vandermeer J, Mitchell A, Kirke PN, Conley MR, Shane B, Scott JM, Brody LC, Mills JL. Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population. Am J Med Genet A. 2011 ;155:14-21.
  161. Mills JL. Malformations in infants of diabetic mothers. Teratology 25:385-94. 1982. Birth Defects Res A Clin Mol Teratol. 2010 ;88:769-78.
  162. Aros S, Mills JL, Iñiguez G, Avila A, Conley MR, Troendle J, Cox C, Cassorla F. Effects of prenatal ethanol exposure on postnatal growth and the insulin-like growth factor axis. Horm Res Paediatr. 2011;75:166-73.
  163. Sutton M, Mills JL, Molloy AM, Troendle JF, Brody LC, Conley M, Mc Donnell R, Scott JM, Kirke PN. Maternal folate, vitamin B12 and homocysteine levels in pregnancies affected by congenital malformations other than neural tube defects.Birth Defects Res A Clin Mol Teratol. 2011 ;91:610-5
  164. Yetley EA, Pfeiffer CM, Phinney KW, Fazili Z, Lacher DA, Bailey RL, Blackmore S, Bock JL, Brody LC, Carmel R, Curtin LR, Durazo-Arvizu RA, Eckfeldt JH, Green R, Gregory JF 3rd, Hoofnagle AN, Jacobsen DW, Jacques PF, Molloy AM, Massaro J, Mills JL, Nexo E, Rader JI, Selhub J, Sempos C, Shane B, Stabler S, Stover P, Tamura T, Tedstone A, Thorpe SJ, Coates PM, Johnson CL, Picciano MF. Biomarkers of folate status in NHANES: a roundtable summary. Am J Clin Nutr. 2011 ;94:303S-312S.
  165. Yetley EA, Pfeiffer CM, Phinney KW, Bailey RL, Blackmore S, Bock JL, Brody LC, Carmel R, Curtin LR, Durazo-Arvizu RA, Eckfeldt JH, Green R, Gregory JF 3rd, Hoofnagle AN, Jacobsen DW, Jacques PF, Lacher DA, Molloy AM, Massaro J, Mills JL, Nexo E, Rader JI, Selhub J, Sempos C, Shane B, Stabler S, Stover P, Tamura T, Tedstone A, Thorpe SJ, Coates PM, Johnson CL, Picciano MF. Biomarkers of vitamin B-12 status in NHANES: a roundtable summary. Am J Clin Nutr. 2011 ;94:313S-321S.
  166. Mills JL, Carter TC, Scott JM, Troendle JF, Gibney ER, Shane B, Kirke PN, Ueland PM, Brody LC, Molloy AM. Do high blood folate concentrations exacerbate metabolic abnormalities in people with low vitamin B-12 status? Am J Clin Nutr. 2011 ;94:495-500.
  167. Cornman-Homonoff J, Kuehn D, Aros S, Carter TC, Conley MR, Troendle J, Cassorla F, Mills JL. Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery. J Matern Fetal Neonatal Med. 2011. in press
  168. Stone N, Pangilinan F, Molloy AM, Shane B, Scott JM, Ueland PM, Mills JL, Kirke PN, Sethupathy P, Brody LC. Bioinformatic and genetic association analysis of microRNA target sites in one-carbon metabolism genes. PLoS One. 2011;6:e21851.
  169. Abrams JY, Schonberger LB, Belay ED, Maddox RA, Leschek EW, Mills JL, Wysowski DK, Fradkin JE. Lower risk of Creutzfeldt-Jakob disease in pituitary growth hormone recipients initiating treatment after 1977. J Clin Endocrinol Metab. 2011;96:E1666-9.
  170. Murphy LE, Mills JL, Molloy AM, Qian C, Carter TC, Strevens H, Wide-Swensson D, Giwercman A, Levine RJ. Folate and vitamin B(12) in idiopathic male infertility. Asian J Androl. 2011 ;13:856-61.
  171. Moslehi R, Kumar A, Mills JL, Ambroggio X, Signore C, Dzutsev A. Phenotype-specific adverse effects of XPD mutations on human prenatal development implicate impairment of TFIIH-mediated functions in placenta. Eur J Hum Genet,2012;20: 626-631.
  172. Mills JL, Carter TC, Kay DM, Browne M, Brody LC, Liu A, Romitti PA, Caggana M, Druschel C, Folate and vitamin B12 related genes and risk for omphalocele. Hum Genet. 2012;131:739-46.
  173. Kuehn D*, Aros S*, Cassorla C, Avaria M, Unanue N, Henriquez C, Kleinsteuber K, Conca B, Avila A, Carter TC, Conley MA, Troendle J, Mills JL. *These authors contributed equally to this manuscript. Alcohol Clin Exp Res. 2012 ;36:1811-9.
  174. Minguzzi S, Molloy AM, Kirke PN, Mills JL, Scott JM, Troendle J, Pangilinan F, Brody LC, Parle-McDermott A. Development of a melting curve assay to genotype a tri-allelic polymorphism of MTHFD1L: an association study of nonsyndromic Cleft in Ireland. BMC Med Genet 2012 ;13:29.
  175. Carter TC, Kay DM, Browne ML, Liu A, Romitti PA, Kuehn D, Conley MR, Caggana M, Druschel CM, Brody LC, Mills JL. Hirschsprung's disease and variants in genes that regulate enteric neural crest cell proliferation, migration and differentiation. J Hum Genet. 2012; 57:485-93.
  176. Pangilinan F, Molloy AM, Mills JL, Troendle JF, Parle-McDermott A, Signore C, O'Leary VB, Chines P, Seay JM, Geiler-Samerotte K, Mitchell A, Vandermeer JE, Krebs KM, Sanchez A, Cornman-Homonoff J, Stone N, Conley M, Kirke PN, Shane B, Scott JM, Brody LC. Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects. BMC Med Genet. 2012;13:62.
  177. Browne ML, Carter TC, Kay DM, Kuehn D, Brody LC, Romitti PA, Liu A, Caggana M, Druschel CM, Mills JL. Evaluation of genes involved in limb development, angiogenesis, and coagulation as risk factors for congenital limb deficiencies. Am J Med Genet A. 2012 ;158A:2463-72.
  178. Carter TC, Kay DM, Browne ML, Liu A, Romitti PA, Kuehn D, Conley MR, Caggana M, Druschel CM, Brody LC, Mills JL. Anorectal atresia and variants at predicted regulatory sites in candidate genes. Ann Hum Genet. 2013;77:31-46
  179. Justice CM, Yagnik G, Kim Y, Peter I, Jabs EW, Erazo M, Ye X, Ainehsazan E, Shi L, Cunningham ML, Kimonis V, Roscioli T, Wall SA, Wilkie AO, Stoler J, Richtsmeier JT, Heuzé Y, Sanchez-Lara PA, Buckley MF, Druschel CM, Mills JL, Caggana M, Romitti PA, Kay DM, Senders C, Taub PJ, Klein OD, Boggan J, Zwienenberg-Lee M, Naydenov C, Kim J, Wilson AF, Boyadjiev SA. A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9. Nat Genet. 2012 ;44:1360-4
  180. Desch KC, Ozel AB, Siemieniak D, Kalish Y, Shavit JA, Thornburg CD, Sharathkumar AA, McHugh CP, Laurie CC, Crenshaw A, Mirel DB, Kim Y, Cropp CD, Molloy AM, Kirke PN, Bailey-Wilson JE, Wilson AF, Mills JL, Scott JM, Brody LC, Li JZ, Ginsburg D. Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association. Proc Natl Acad Sci U S A. 2013 ;110:588-93
  181. Irwin DJ, Abrams JY, Schonberger LB, Leschek EW, Mills JL, Lee VM, Trojanowski JQ. Evaluation of potential infectivity of Alzheimer and Parkinson disease proteins in recipients of cadaver-derived human growth hormone. JAMA Neurol. 2013 ;70:462-8
  182. Mamasoula C, Prentice RR, Pierscionek T, Pangilinan F, Mills JL, Druschel C, Pass K, Russell MW, Hall D, Töpf A, Brown DL, Zelenika D, Bentham J, Cosgrove C, Bhattacharya S, Riveron JG, Setchfield K, Brook JD, Bu'Lock FA, Thornborough C, Rahman TJ, Doza JP, Tan HL, O'Sullivan J, Stuart AG, Blue G, Winlaw D, Postma AV, Mulder BJ, Zwinderman AH, van Engelen K, Moorman AF, Rauch A, Gewillig M, Breckpot J, Devriendt K, Lathrop GM, Farrall M, Goodship JA, Cordell HJ, Brody LC, Keavney BD. Association between C677T polymorphism of methylene tetrahydrofolate reductase and congenital heart disease: meta-analysis of 7697 cases and 13,125 controls. Circ Cardiovasc Genet. 2013;6:347-53
  183. Moslehi R, Mills JL, Signore C, Kumar A, Ambroggio X, Dzutsev A. Integrative transcriptome analysis reveals dysregulation of canonical cancer molecular pathways in placenta leading to preeclampsia. Sci Rep. 2013;3:2407
  184. Feenstra B, Geller F, Carstensen L, Romitti PA, Körberg IB, Bedell B, Krogh C, Fan R, Svenningsson A, Caggana M, Nordenskjöld A, Mills JL, Murray JC, Melbye M. Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis. JAMA. 2013;310:714-21
  185. Fan R, Wang Y, Mills JL, Wilson AF, Bailey-Wilson JE, Xiong M Functional linear models for association analysis of quantitative traits. Genet Epidemiol. 2013 Nov;37(7):726-42.
  186. Molloy AM, Einri CN, Jain D, Laird E, Fan R, Wang Y, Scott JM, Shane B, Brody LC, Kirke PN, Mills JL.
    Is low iron status a risk factor for neural tube defects? Birth Defects Res A Clin Mol Teratol. 2014 ;100:100-6
  187. Li Q, Xiong W, Chen J, Zheng G, Li Z, Mills, JL, Liu A. A robust test for quantitative trait analysis with model uncertainty in genetic association studies. Statistics and Its Interface 2014; 7:61-68
  188. Brite J, Laughon SK, Troendle J, Mills J. Maternal overweight and obesity and risk of congenital heart defects in offspring. Int J Obes (Lond). 2013 Jun;38:878-82
  189. Bao W, Tobias DK, Bowers K, Chavarro J, Vaag A, Grunnet LG, Strøm M, Mills J, Liu A, Kiely M, Zhang C.
    Physical activity and sedentary behaviors associated with risk of progression from gestational diabetes mellitus to type 2 diabetes mellitus: a prospective cohort study. JAMA Intern Med. 2014 ;174:1047-55
  190. Zhang C, Hu FB, Olsen SF, Vaag A, Gore-Langton R, Chavarro JE, Bao W, Yeung E, Bowers K, Grunnet LG, Sherman S, Kiely M, Strøm M, Hansen S, Liu A, Mills J, Fan R; the DWH study team. Rationale, design, and method of the Diabetes & Women's Health study - a study of long-term health implications of glucose intolerance in pregnancy and their determinants. Acta Obstet Gynecol Scand. 2014 e published
  191. Ma Q, Ozel AB, Ramdas S, McGee B, Khoriaty R, Siemieniak D, Li HD, Guan Y, Brody LC, Mills JL, Molloy AM, Ginsburg D, Li JZ, Desch KC. Genetic variants in PLG, LPA and SIGLEC 14 as well as smoking contribute to plasma plasminogen levels. Blood. 2014 Sep 10 [Epub ahead of print]
  192. Rigler SL, Kay DM, Sicko RJ, Fan R, Liu A, Caggana M, Browne ML, Druschel CM, Romitti PA, Brody LC, Mills JL. Novel copy-number variants in a population-based investigation of classic heterotaxy. Genet Med. 2014 Sep 18 [Epub ahead of print]
  193. Mills JL, Fan R, Brody LC, Liu A, Ueland PM, Wang Y, Kirke PN, Shane B, Molloy AM. Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects. Am J Clin Nutr. 2014 Oct;100(4):1069-74
  194. Yeung EH, Liu A, Mills JL, Zhang C, Männistö T, Lu Z, Tsai MY, Mendola P. Increased Levels of Copeptin Before Clinical Diagnosis of Preelcampsia. Hypertension. 2014 Sep 15. [Epub ahead of print]
  195. Pangilinan F, Molloy AM, Mills JL, Troendle JF, Parle-McDermott A, Kay DM, Browne ML, McGrath EC, Abaan H, Sutton M, Kirke PN, Caggana M, Shane B, Scott JM, Brody LC. Replication and exploratory analysis of 24 candidate risk polymorphisms for neural tube defects. BMC Med Genet. 2014 ;15:102.
  196. International League Against Epilepsy Consortium on Complex Epilepsies. Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies. Lancet Neurol. 2014 ;13:893-903

Non-refereed Manuscripts

  1. Mills JL, Bongiovanni A. Effect on male genitalia of prenatal estrogens. Pediatr 1978; 62:1160-1165.
  2. Report of the Second International Workshop - Conference on Gestational Diabetes. Summary and recommendations IV. Prognostic considerations. Diabetes 1986; 34:126 (suppl. 2).
  3. O'Sullivan J, Harris MI, Mills JL. Diabetes in pregnancy. In: Diabetes in America. Diabetes Data Compiled 1984. Department of Health and Human Services. NIH Publication No. 85-1468, Chapter XX, 1985, pp. 1-17.
  4. Mills JL, O'Sullivan J. Infants of diabetic mothers. In: Diabetes in America. Diabetes Data Compiled 1984. Department of Health and Human Services. NIH Publication No. 85-1468, Chapter XXI, 1985, pp. 1-19.
  5. Mills JL. Reporting provocative results: Can we publish "hot" papers without getting burned (Commentary). JAMA 1987; 258:3428-3429.
  6. Mills JL. Commentary. Diabetes Spectrum: From Research to Practice 1990; 3:165-166.
  7. Mills JL. Fertility drugs and neural tube defects: Why can't we make up our minds? Teratol 1990; 42:595-596. (Invited Commentary incorrectly listed as Letter)
  8. Mills JL. Commentary. Diabetes Spectrum: From Research to Practice 4:218, 1991.
  9. Mills JL. Protecting the embryo from x-rated drugs. N Engl J Med 1995; 333:124-5.
  10. Mills JL. Cocaine, smoking, and spontaneous abortion. N Engl J Med 1999; 340:380-81.
  11. Mills JL. Folate and oral clefts: where do we go from here? New directions in oral clefts research. Teratol 1999; 60:251-252.
  12. Mills JL, England L. Food fortification to prevent neural tube defects: is it working? JAMA 2001; 285:3022-3.
  13. Statement of the Public Affairs Committee of the Teratology Society on the Importance of Smoking Cessation during Pregnancy [contributing author and committee member]. Jane Adams lead author. Birth Defects Research (Part A) 2003; 67: 895-899.
  14. The Public Affairs Committee of the Teratology Society [Member of the Committee] Causation in teratology-related litigation. Birth Defects Research Part A: Clinical and Molecular Teratology 2005; 73:421-423.
  15. The Public Affairs Committee of the Teratology Society [Member of the Committee].
    Maternal Obesity and Pregnancy. Birth Defects Research Part A: Clinical and Molecular Teratology 2006; 76:73-77.
  16. Mills JL. Depressing observations on the use of selective serotonin-reuptake inhibitors during pregnancy. N Engl J Med 2006; 354:636-8.
  17. Molloy AM, Kirke PN, Brody LC, Scott JM, Mills JL. Effects of folate and vitamin B12 deficiencies during pregnancy on fetal, infant and child development. Food and Nutrition Bulletin 2008; 29 Suppl 2: S101-111.
  18. Mills JL, Carter TC. Preventing neural tube defects and more via food fortification? Am J Epidemiol 2009; 169: 18-21.
  19. Acyclovir exposure and birth defects: an important advance, but more are needed. Mills JL, Carter TC.
    JAMA. 2010 ;304:905-6.
  20. Mills JL. Malformations in infants of diabetic mothers. Teratology 25: 385-94. 1982. Birth Defects Res A Clin Mol Teratol. 2010 ;88:769-78 [Selected “Classic Paper” celebrating 50th anniversary of the Teratology Society]

Invited Book Chapters

  1. Koppe J, Smorenberg-Schoorl M, van den Berg-Loonen E, Mills JL. Diabetes, congenital malformations and HLA types. In: Stern L, Bard H, and Friis-Hansen B (eds.). Intensive Care in the Newborn, vol. 4. Masson Publishing, New York, 1983, pp. 15-18.
  2. Workgroup - National Diabetes Advisory Board. Pregnancy and fetal malformations. In: Progress and Promise in Diabetes Research: Report of the Second National Diabetes Research Conference. National Diabetes Advisory Board. Department of Health and Human Services. NIH Publication No. 84-661, 1984, pp. 87-95.
  3. Simpson JL, Mills JL. Methodologic problems in determining fetal loss rates: Relevance to chorionic villi sampling. In: Fraccaro M, Simoni G, Brambati B (eds.). First Trimester Fetal Diagnosis. Springer-Verlag, New York, 1985, pp. 321-333.
  4. Mills JL. Endocrinology of premature thelarche. In: John McLachlan (ed.). Estrogens in the Environment II: Influences on Development. Elsevier, New York, 1985, pp. 412-427.
  5. Cordero JF, Haddock L, Lebron G, Martinez R, Freni-Titulaer LW, Mills JL. Premature thelarche in Puerto Rico: Design of a case-control study. In: John McLachlan (ed.). Estrogens in the Environment II. Elsevier, New York, 1985, pp. 380-395.
  6. Simpson JL, Mills JL. Methodologic problems in determining fetal loss rates. In: Brambati B, Simoni G, Fabro (eds.). Chorionic Villus Sampling: Fetal Diagnosis of Genetic Diseases in the First Trimester. Marcel Dekkar, New York, 1986, pp. 227-257.
  7. Rotter J, Mills JL. Diabetes mellitus. In: Berini RY, Kahn E (eds.). Clinical Genetics Handbook. Medical Economics, Oradell, New Jersey, 1986, pp. 227-234.
  8. Mills JL, Withiam M. Diabetes, pregnancy, and malformations: An epidemiologic perspective. In: Jovanovic L, Peterson CM, Fuhrmann K (eds.). Diabetes and Pregnancy: Teratology, Toxicity and Treatment. Praeger, New York, 1986, pp. 3-14.
  9. Jovanovic L, Mills JL, Peterson CM. Rationale for the use of human insulin in pregnancy. In: Jovanovic L, Peterson CM, Fuhrmann K (eds.). Diabetes and Pregnancy: Teratology, Toxicity and Treatment. Praeger, New York, 1986, pp. 157-167.
  10. Mills JL, Graubard BI. La controversia sugli effetti del bere moderatamente durante la gravidanza. In: Pachi A, Astrei G (eds.). Tutela Della Salute Della Gestante e del Concepito. Acta Medica, Rome, 1986, pp. 123-128.
  11. Simpson JL, Mills JL, Knopp RH, Jovanovic L, Metzger BE, NICHD-DIEP. Congenital anomalies and type I diabetes mellitus. Proceedings of 12th Meeting International Federation Obstetrics and Gynecology. Rio de Janeiro, 1988, J.A. Pinotti, P. Belfort, eds., Parthenon, Lancaster, U.K.
  12. Mills JL. Spermicides and Birth Defects. In: Phantom Risk: Scientific Inference and the Law, Foster KR, Bernstein DE, Huber PW (eds.). MIT Press, 1993, pp. 87-100.
  13. Simpson JL, Mills JL, Ober C, Holmes L, Knopp R, Jovanovic-Peterson L, Metzger B, Aarons J, Conley M, Reed G, and the NICHD-DIEP. Is there a genetic basis for diabetic teratogenicity? In: The Current Status of Gynaecology and Obstetric Series, Proceedings of the XIIIth World Congress of Gynaecology and Obstetrics, Singapore, September 1991, Volume 2: Fetal Physiology and Pathology, Teoh E-S, Ratnam SS, Macnaughton M (eds.). Parthenon Publishing Group, 1993, pp.119-125.
  14. Simpson JL, Mills JL, Rhoads G, Cunningham G. Genetic heterogeneity and neural tube defects: relevance to folate-responsiveness. Care, Concern and Cure. Proceedings of the XIII European Congress on Perinatal Medicine, Amsterdam, May 1992, Parthenon Publ.
  15. Mills JL. Birth defects. Congressional Record 1996; 141:E1743-4.
  16. Klebanoff MA, Read J, Mills JL, Shiono PH. Neonatal vitamin K administration and cancer during childhood. In: Sutor A, Hathaway W, eds. Proceedings of the International Symposium on Vitamin K in Infancy. Stuttgart, Germany: 1995, 303-313.
  17. Carson SA, Mills JL, Metzger B, Jovanovic-Peterson L, Knopp R, Conley M, Simpson JL. How significant are non-genetic factors in spontaneous abortions? (In) New Horizons in Reproductive Medicine, Parthenon Publishing Group, New York, C. Coutifaris and L. Mastroianni, eds., 1997, pp 501-506.
  18. Molloy AM, Ramsbottom D, McPartlin J, Whitehead AS, Weir DG, Scott JM, Kirke PN, Burke H, Daly S, Mills JL, Conley M. 5,10-Methylenetetrahydrofolate reductases C677T genotypes and folate related risk factors for neural tube defects. In:W. Pfleiderer, H. Rokos, eds. Chemistry and Biology of Pteridines and Folates 1997: Proceedings of the Eleventh International Symposium on Pteridines and Folates, Berchtesgaden, Germany, June 15-20, 1997. Berlin: Blackwell Science; 1997: 291-296.