The Effect of Perinatal Exposure to Persistent Organochlorine Compounds on Child Health and Development from Birth to Age Two
Principal investigator: Courtney Denning-Johnson Lynch, Ph.D, M.P.H.
Persistent organochlorine compounds (POCs) such as polychlorinated biphenyls (PCBs) and chlorinated pesticides, are ubiquitous in the environment. While production of PCBs in the United States ended in 1977, they persist in the environment due to prior manufacturing releases, accidental spills and leaks, and improper storage and dumping. POCs have been shown to cross the placenta and are excreted in breast milk, thereby exposing the developing fetus and infant. This study uses data from the New York State Angler Cohort Prospective Pregnancy Study to examine whether or not infant growth, development, and health are affected by prenatal and childhood exposure to PCBs and organochlorine pesticides.
DESPR Collaborators
· Germaine M. Buck Louis, Ph.D., M.S.
· Enrique F. Schisterman, Ph.D.
Selected Publications
Senn KM, McGuinness BM, Buck GM, Vena JE, Anderson S, & Rogers BT. (2005). Longitudinal study of babies born to mothers enrolled in a preconception prospective pregnancy study: Study design and methodology, New York State Angler Cohort Study. Environmental Research, 97(2):163-169. [Abstract]