Marie Elizabeth Thoma, Ph.D, M.H.S.

Address:

DESPR, NICHD, NIH
6100 Executive Blvd, #7B03B
Bethesda, MD 20892

Contact Information:

Phone: 301-435-2295
Email: thomame@mail.nih.gov

EDUCATION

January 2010 -present
Bethesda, MD
Postdoctoral Fellow, Intramural Research Training Award Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health
November 2009
Baltimore, MD
PhD, Reproductive Epidemiology concentration Department of Population, Family, and Reproductive Health Johns Hopkins Bloomberg School of Public Health Thesis: “The Epidemiology and Natural History of Bacterial Vaginosis in Rakai, Uganda” Advisor: Dr. Ronald Gray
November 2009
Baltimore, MD
MHS, Department of Biostatistics Johns Hopkins Bloomberg School of Public Health Advisor: Dr. Mei-Cheng Wang
May 2000
Philadelphia, PA
B.A., Anthropology, minor in Nutrition, summa cum laude College of Arts and Sciences, University of Pennsylvania Honors Thesis: “Diversity and the University: Social Options for a Diverse Campus” Advisor: Dr. Francis E. Johnston
Fall 1998
Samoa/Fiji
Pacific Island Studies School for International Training Independent Study: “The Socioeconomic Impact of Marine Conversation in Aliepata, Samoa”

PROFESSIONAL EXPERIENCE

June 2005 – July 2009
Baltimore, MD
Research Assistant Johns Hopkins Bloomberg School of Public Health Research Projects: Rakai Health Sciences Program; Prognosis, Improvements in Quality of Life, and Social Integration of Women with Obstetric Fistula after Surgical Treatments study; Iron Supplementation in Adolescent girls in West Bengal, India
May 2008 – June 2008
Washington D.C.
Research Assistant Save the Children, Saving Newborn Lives Survey-based Indicators for Monitoring and Evaluation of Newborn Health Programs
Aug 2002 – Aug 2004
Baltimore, MD
Research Program Coordinator Johns Hopkins Bloomberg School of Public Health
Nov 2000 – July 2002
New York, NY
Research Program Coordinator Mailman School of Public Health, Columbia University
1999 – 2000
Philadelphia, PA
Research Assistant Department of Anthropology, University of Pennsylvania
May 1999 – Aug 1999
Washington D.C.
Administrative Liaison International Fund for Agricultural Development

TEACHING

Summer 2011, 2012 Lecturer, Reproductive Health Studies in Child Health and Human Development, DESPR, NICHD, NIH
April 2011 Lecturer, Issues in Reproductive Epidemiology Research Fellows Seminar, DESPR, NICHD, NIH
Spring 2009 Teaching Assistant, Statistical Methods in Public Health IV Johns Hopkins Bloomberg School of Public Health
2007 – 2008 Teaching Assistant, Methods in Biostatistics I-IV Johns Hopkins Bloomberg School of Public Health
Spring 2006, 2007 Teaching Assistant, Reproductive and Perinatal Epidemiology Johns Hopkins Bloomberg School of Public Health
2006 – 2008 Tutor, Statistical Methods in Public Health Johns Hopkins Bloomberg School of Public Health
2006 Tutor, Principles of Epidemiology Johns Hopkins Bloomberg School of Public Health

MENTORING

Summer 2010 K. Leanne Sanders, Summer Fellow, NICHD, NIH (Co-mentor)
2012 J. Fredo Louis, Postbaccalaureate Fellow, NICHD, NIH (Co-mentor)

HONORS AND AWARDS

2010 Delta Omega Honors Society, Johns Hopkins University
2009 – 2010 Caroline Cochran Scholarship Fund, Johns Hopkins University
2008 – 2009 The R. Bradley Sack Family Scholarship Award for Infectious Diseases in the Developing World, Johns Hopkins University
2008 – 2009 Endowed Fellowship in Family Planning and Reproductive Health, Johns Hopkins University
2006 – 2007 Endowed Fellowship in Family Planning and Reproductive Health, Johns Hopkins University
2000 Golden Key International Honors Society, University of Pennsylvania
2000 Mortar Board National Honors Society, University of Pennsylvania

PROFESSIONAL MEMBERSHIPS

Alpha Chapter of the Delta Omega Honors Society in Public Health
American Public Health Association
American Sexually Transmitted Disease Association
Society for Epidemiologic Research
Society for Pediatric and Perinatal Epidemiologic Research
American Statistical Association

RESEARCH SUPPORT

Aug 2009 – Dec 2009 Predoctoral Fellowship
Role: Predoctoral Fellow (Mentor: Dr. Mark Klebanoff)
Agency: National Institute of Child Health and Human Development
Type: Intramural Research Training Award
April 2008 – March 2009 The Natural History of Bacterial Vaginosis and Modes of Transmission, Rakai, Uganda
Role: Principal Investigator
Agency: Center for Disease Control and Prevention
Type: R36PS001104-01
A dissertation training award to investigate the natural history of and risk factors for BV and vaginal flora changes among a cohort of pre-and postmenarcheal women in Rakai, Uganda
Sept 2004 – May 2007 Johns Hopkins Sexually Transmitted Diseases Training Center Grant
Role: Predoctoral Fellow (PI: Dr. Jonathan Zenilman)
Agency: National Institute of Allergy and Infectious Diseases
Type: T32A1050056

RESEARCH ACTIVITIES

Microbial Diversity of Water Sources, Rakai, Uganda
Role: Epidemiologist (PI: Drs. Ronald Gray and Maria Wawer)
Agency: Rakai Health Sciences Program
Type: n/a
A pilot project to describe bacterial species present in water from different sources in communities enrolled in the Rakai Health Sciences Program ongoing cohort using 16S rRNA sequencing

The Effect of Diet on Bacterial Vaginosis (BV) and Periodontal Disease (PD)
Role: Co-Principal Investigator (Co-PI: Dr. Alisha Rovner)
Agency: National Institute of Child Health and Human Development
Type: Intramural
To assess the association between diet and dietary indices from food frequency questionnaires on BV and PD from the Longitudinal Study of Vaginal Flora (LSVF)

Microbial Diversity of Vaginal, Stool, and Uretheral Samples in Infants
Role: Principal Investigator
Agency: National Institute of Child Health and Human Development/National Institute of Environmental Health Sciences
Type: Intramural
A pilot project to describe bacterial species collected from infants at 1 and 12 weeks of age from different sites (vagina, stool, and urethra) using 16S rRNA sequencing to inform future studies on vertical transmission of microflora

New York State Infant Development Screening Program (Upstate KIDS)
Role: Postdoctoral Researcher (PI: Dr. Mary Hediger)
Agency: National Institute of Child Health and Human Development
Type: Intramural
To determine whether infertility treatments, such as ovulation-stimulating medications and various assisted reproductive technologies (ART), adversely affect the growth, motor, and social development of children from birth through age three years

Endometriosis Natural History, Diagnosis, and Outcomes (ENDO) Study
Role: Postdoctoral Researcher (PI: Dr. Germaine Buck Louis)
Agency: National Institute of Child Health and Human Development
Type: Intramural
To assess the relation between exposure to persistent environmental chemicals and the incidence and severity of endometriosis using a matched-exposure cohort design to recruit women from geographic areas with known environmental contamination who were undergoing laparoscopy

Approaches for assessing trends in infertility
Role: Principal Investigator
Agency: National Institute for Child Health and Human Development Type: Intramural To assess determinants and trends in infertility using different methodologic approaches within the National Survey of Family Growth

Validation Study of Retrospectively Reported Time-to-Pregnancy Data
Role: Postdoctoral Researcher (PI: Dr. Rajeshwari Sundaram)
Agency: National Institute for Child Health and Human Development
Type: Intramural To compared the validity at 3 to 4 years of male and female recalled time to pregnancy (TTP) and other covariates with their original prospective pregnancy study using the Longitudinal Investigation of Fertility and the Environment (LIFE) Study, which utilized a prospective cohort design suitable for following couples across sensitive windows of human reproduction and development.

PUBLICATIONS AND REPORTS

Peer-Reviewed Manuscripts

Thoma ME, Hediger ML, Sundaram R, Chen Z, Peterson CM, Croughan MS, Buck Louis GM, for the ENDO Study Working Group. Comparing “apples and pears”: How well do women perceive their body size and shape? J Women’s Health. 2012. (Accepted)

Sanders KL, Thoma ME, Yu K, Albert PS. An evaluation of the natural history of bacterial vaginosis using transition models. Sex Transm Dis. 2011 Dec;38(12):1131-6. [PMID: 22082724]

Thoma ME, Gray RH, Kiwanuka N, Wang MC, Sewankambo N, Wawer M. The natural history of bacterial vaginosis (BV) diagnosed by Gram stain among women in Rakai, Uganda. Sex Transm Dis. 2011 Nov;38(11):1040-1045. [PMID: 21992981]

Thoma ME, Klebanoff M, Rovner A, Nansel T, Neggers Y, Andrews W, Schwebke J. Bacterial vaginosis (BV) is associated with dietary indices. J Nutr. 2011, Sep;141(9):1698-704. [PMID: 21734062]

Thoma ME, Gray RH, Kiwanuka N, Wang MC, Aluma S, Sewankambo N, Wawer M. The Short-term Variability of Bacterial Vaginosis (BV) Diagnosed by Nugent Gram Stain Criteria among Sexually Active Women in Rakai, Uganda. Sex Transm Dis. 2011 Feb;38(2):111-6. [PMID: 20921931]

Thoma ME, Gray RH, Kiwanuka N, Wang MC, Aluma S, Sewankambo N, Wawer M. Longitudinal changes in vaginal microbiota composition assessed by Gram-stain among never sexually active pre-and postmenarcheal adolescents in Rakai, Uganda. J Pediatr Adolesc Gynecol. 2011 Feb;24(1):42-7. [PMID: 20709584]

Submitted Manuscripts

Cheon K, Thoma ME, Kong X, Albert PS. A mixture of Markov models for heterogeneous longitudinal ordinal data: with applications to longitudinal bacterial vaginosis data, 2012.

Hunsberger S, Albert P, Thoma ME. Approaches for retrospective sampling for longitudinal transition regression models. 2012.

Manuscripts in Preparation

Thoma ME, Louis JF, McLain AC, King RB, Trumble AC, Sundaram R, Buck Louis GM. A comparison of measurement approaches for estimating the prevalence of infertility in the National Survey of Family Growth.

Louis JF, Thoma ME, McLain AC, King RB, Trumble AC, Sundaram R, Buck Louis< GM. Prevalence of couple infertility in the US based on male reporting: evidence from a nationally-representative survey.

Thoma ME, Gray RH, Kiwanuka N, Wang MC, Aluma S, Sewankambo N, Wawer M. Risk and protective factors for persistent BV among a cohort of reproductive-aged women in Rakai, Uganda.

Thoma ME, Klebanoff MA, Nansel TR, Hediger ML, Neggers Y, Jeffcoat M, Rovner A. The association between periodontal disease (PD) and dietary fats and cholesterol.

Research Letters

Thoma M, Gray RH, Kiwanuka N, Serwadda D, Wawer M. Unsafe injections and transmission of HIV-1 in sub-Saharan Africa. Lancet. 2004 May 15; 363(9421):1650-1. [PMID: 15145649]

Gray RH, Thoma M, Kiwanuka N, Serwadda D, Wawer M. HIV transmission through health care in sub-Saharan Africa. Lancet. 2004 Nov.6-12; 364(9446):1666.

Reports

Report of a Consultative Meeting on Survey-based Indicators for Monitoring and Evaluation of Newborn Health Programs April 29-30, 2008. Save the Children, Saving Newborn Lives. [prepared initial draft]

PRESENTATIONS AND INVITED TALKS

Thoma ME, Louis JF, McLain AC, King RB, Trumble AC, Sundaram R, Buck Louis GM. A comparison of measurement approaches for estimating the prevalence of infertility in the National Survey of Family Growth. Oral presentation at the 2012 Meeting of the Society for Pediatric and Perinatal Epidemiologic Research, June 2012, Minneapolis, MN.

Louis J, Thoma M, Trumble A. Prevalence of couple infertility in the US based on male reporting: evidence from a nationally-representative survey. Poster presentation at the NIH Spring Research Festival, April 2012, Bethesda, MD.

Cheon K, Thoma ME, Kong X, Albert PS. A mixture of Markov models for heterogeneous longitudinal ordinal data: with applications to analyzing longitudinal bacterial vaginosis data. Oral presentation at the Eastern North American Region of the International Biometric Society Spring Meeting, April 2012, Washington D.C.

Thoma ME, Hediger ML, Sundaram R, Chen Z, Peterson CM, Croughan MS, Buck Louis GM, for the ENDO Study Working Group. Comparing “apples and pears”: How well do women perceive their body size and shape? Oral presentation at the American Society for Reproductive Medicine 67th Annual Meeting, October 2011, Orlando, FL.

Thoma ME, Klebanoff MA, Nansel TR, Hediger ML, Neggers Y. The association between periodontal disease (PD) and dietary fats and cholesterol. Poster presentation at the 2011 Meeting of the Society for Pediatric and Perinatal Epidemiologic Research, June 2011, Montreal, Canada.

Thoma M, Gray RH, Kiwanuka N, Wang MC, Aluma S, Sewankambo N, Wawer M. The Short-term Variability of Bacterial Vaginosis (BV) among Sexually Active Women in Rakai, Uganda. Poster presentation at the 2010 Meeting of the Society for Epidemiologic Research, June 2010, Seattle, WA.

Thoma M, Gray RH, Kiwanuka N, Wang MC, Aluma S, Sewankambo N, Wawer M. Don’t throw BV out with the bathwater: risk and protective factors for bacterial vaginosis (BV) in Rakai, Uganda. Poster presentation at the 23rd Annual Meeting of the Society for Pediatric and Perinatal Epidemiologic Research, June 2010, Seattle, WA.

Thoma M, Gray R, Kiwanuka N, Serwadda D, Nalugoda F, Kigozi G, Wang M, Aluma S, Ndyanabo A, Wawer MJ. Stage of Puberty and Vaginal Flora Development. Poster presentation at the 18th International Society for Sexually Transmitted Disease Research, July 2009. London, England.

Thoma M, Gray R. Male Circumcision and Genital Ulcer Disease: A meta-analysis. Poster presentation at the 17th International Society for Sexually Transmitted Disease Research, July 2007. Seattle, WA.

Gray R, Wawer M, Thoma M, Serwadda D, Nalugoda F, Li X, Kigozi G, Kiwanuka N, Laeyendecker, Quinn T. Male Circumcision and the risks of female HIV and sexually transmitted infections acquisition in Rakai, Uganda. Oral presentation at the 13th Conference on Retroviral and Opportunistic Infections, February 2006. Denver, CO.

PROFESSIONAL ACTIVITIES AND SERVICE

Editorial Activities (Ad Hoc Reviewer)

American Journal of Epidemiology
British Journal of Obstetrics and Gynecology
Journal of Infectious Diseases in Obstetrics and Gynecology
Maternal and Child Health Journal
Society for Pediatric and Perinatal Epidemiology (SPER)
Society for Epidemiologic Research (SER)
Cochrane Review Group on HIV/AIDS
Indian Journal of Medical Research

Grant and Contract Review

Technical Reviewer for RFP “Validation of Retrospectively Reported Time to Pregnancy Data”

Journal Clubs and Seminars:

Reproductive Health Journal Club, NICHD (2009-present)
Epidemiologic Methods Journal Club, NICHD (2009-present)
Postdoctoral Epidemiology series, coordinator for Reproductive/Nutritional
Epidemiology (2011)
Reproductive Endocrinology for Epidemiologists, coordinator (2010-2011)
Sexually Transmitted Infections Journal Club, JHU (2005-2009)
Biostatistics MHS Journal Club, JHU, coordinator (2007-2008)
Sexually Transmitted Infections Seminar series, JHU, coordinator (2005-2007)

Committees:

Population, Family, and Reproductive Health Departmental Research Day (2006-2007)
Mortar Board National Senior Honors Society Executive Board (1999-2000)

PROFESSIONAL DEVELOPMENT

Certificates and Training

Managing Federal Grants and Cooperative Agreements for Recipients (2004), Management Concepts

One-day training on BV diagnosis and scoring, Dr. Sharon Hillier’s Lab, Magee Women’s Research Institute (2008)

Institute for Genome Sciences, Genomics Workshop at the University of Maryland School of Medicine (April 20-23, 2010)

Contractor Performance Assessment Reporting System (February 14th, 2011)

Good Clinical Practice Certification, NIAID, NIH (April 2011)

Introduction to R, Computer Training Program, Center for Information Technology, NIH (May 2011)

Contract Officer Representative Training, HHS University, online (October-present, 2012)

Measurement Error in Dietary Intake Data Webinar Series, Cancer Control and Population Sciences, National Cancer Institute (September – December, 2011)

Media Training, Oratorio Media and Presentation Training, Washington D.C. (November 2, 2011)

SAS Enterprise Guide 1: Querying and Reporting, Computer Training Program, Center for Information Technology, NIH (January 2012)

SAS Programming Essentials for Experienced SAS Enterprise Guide Users, Computer Training Program, Center for Information Technology, NIH (February 2012)

Software

STATA (advanced), R, SAS, Cochrane Collaboration Review Manager, Reference Manager, and Microsoft Office, Excel, Access, Power Point

Languages

German proficiency (writing and reading)

Work-related Travel

Uganda (2001, 2009); Samoa/Fiji (1998)