January 17, 2012 (10 am to 11 am)
Office of the Director, NICHD
Balcony A, Natcher Building (Building 45), NIH Main Campus, Bethesda, Maryland
NICHD Director Alan E. Guttmacher, M.D., initiated the NICHD Director’s Lecture Series as a way to showcase cutting-edge science relevant to the Institute’s mission. The forum also enables staff and other attendees to interact with other nationally recognized scientists.The Series starts off 2012 with Pharmacogenomics: Beyond Biomarkers, featuring Richard Weinshilboum, M.D., of the Mayo Clinic in Rochester, Minnesota. Dr. Weinshilboum is the Mary Lou and John H. Dasburg Professor for Cancer Genomics Research, the chair of the Division of Clinical Pharmacology, and a professor of Molecular Pharmacology & Experimental Therapeutics and Medicine. He is also a principal investigator on several NIH grants, including one from the NICHD.Pharmacogenomics is the study of the role of inheritance in variations to drug response phenotypes, which can range from a mild lack of the desired drug efficacy to serious adverse drug reactions. During his presentation, Dr. Weinshilboum will briefly review the origins of pharmacogenomics in pharmacogenetic studies of single genes—often genes that encode drug metabolizing enzymes or drug transporters—followed by examples of the use of genome-wide techniques to pursue drug response phenotypes. Although pharmacogenomics is often thought of as a “translational” science, Dr. Weinshilboum will also provide examples that illustrate the use of pharmacogenomics as discovery science, illuminating novel biology and novel mechanisms of drug response.
The NICHD Director’s Lecture Series is open to the public, and registration is not required. Non-NIH employees should visit http://www.nih.gov/about/visitor/index.htm for details about getting to the NIH campus and security procedures.
Dr. Lynne Haverkos, Child Development and Behavior Branch, Center for Research for Mothers and Children, NICHDTel: (301) 435-6881E-mail: firstname.lastname@example.org
Individuals with disabilities who need sign language interpreters and/or reasonable accommodations to participate should contact Tiffany Ray (email@example.com or 301-594-1968) or the Federal TTY Relay Number (1-800-877-8339). Please make your requests at least five days in advance of the event.
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