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International Workshop on Phosphodiesterases (PDE2009): Their Genetics, Function & Human Disease - Roster

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June 7-9, 2009


Day 1: Monday, June 8, 2009
Day 2: Tuesday, June 9, 2009

For more details on individual speakers, see the conference roster.

Day 1: Monday, June 8, 2009

9:00-9:45 am

Introductory Lecture: GNAS Mutations and Endocrine Disorders
L.S. Weinstein
National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland

9:45-10 am


Session I
PKA: Structure and Function and Insight from Human Disease and Mice

10:00-10:30 am

S. Taylor
University of California, San Diego, California
Title of talk: TBA

10:30-11:00 am

K. Taskén
University of Oslo, Norway
AKAP specificity and spatial dynamic of PKA regulatory subunits

11:00-11:30 am

C. Stratakis
Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland
Insight on cAMP pathway dysregulation in endocrine tumors from the study of PRKAR1A mutations

11:30 am-12:00 pm

Break (Poster Viewing)

12-12:30 pm

L. Kirschner
Ohio State University, Columbus, Ohio
Insight on PKA from PRKAR1A targeted inactivation in transgenic mice

12:30-1:00 pm

A. Lania
University of Milan, Italy
Expression and function of PKA regulatory units in endocrine-related tissues

1:00-1:30 pm

G. Langsley
Faculté de Médecine Paris Descartes - Hôpital Cochin, Paris, France
AMP-dependent protein kinase in infectious diseases

1:30-2:30 pm

Lunch Break (Poster Viewing)

Session IIA
GNAS Locus: Structure and Function

2:30-3:00 pm

G. Kelsey
The Babraham Institute, Cambridge, United Kingdom
Imprinted genes and energy homeostasis

3:00-3:30 pm

H. Jüppner
Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts
The GNAS locus and Pseudohyporathyroidism

3:30- 4:00 pm

P. Bianco
La Sapienza University, Rome, Italy
GNAS transcripts in skeletal progenitors

4:00-4:30 pm

Break (Poster Viewing)

Session IIB
Human Diseases Associated with GNAS Mutations

4:30-5:00 pm

G. Mantovani
University of Milan, Italy
Clinical and laboratory findings in patients with epigenetic defects at the GNAS locus

5:00-5:30 pm

Eileen Shore
The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Diagnostic and mutational spectrum of progressive osseous heteroplasia (POH) and other forms of GNAS-based heterotopic ossification

5:30- 6:00 pm

K. Freson
University of Leuven, Leuven, Belgium
XLalpha, its cofactor ALEX and blood platelet function

7:00 pm–10:00


Day 2: Tuesday, June 9, 2009

Session IIIA
PDEs: Structure and Function

9:00-9:30 am

M. Conti
University of California, San Francisco, California
Cyclic Nucleotide Phosphodiesterases: Molecular Regulation

9:30-10:00 am

G. Vandecasteele
Faculté de Pharmacie, Châtenay-Malabry Cedex, France
Spatiotemporal dynamics of cAMP signals: lessons from myocytes

10:00-10:30 am

M.D. Houslay
University of Glasgow, Glasgow, Scotland, United Kingdom
PDEs in cAMP cell signalling compartimentalization

10:30-11:00 am

Break (Poster Viewing)

Session IIIB
PDEs in Human Diseases

11:00-11:30 am

J. Bertherat 
Institute Cochin, Paris, France
Genetics of Phosphodiesterase 11A in patients with ACTH independent adrenocortical lesions

11:30 am-12:00 pm

A. Horvath
Eunice Kennedy Shriver National Institute of Child Health & Human Development, Bethesda, Maryland
PDE8B, PDE7A and other cAMP-binding PDEs and endocrine tumorigenesis 

12:00-12:30 pm

Dr. J. Beavo
University of Washington, Seattle, Washington
PDE as therapeutical targets


Dr. V. Manganiello
National Heart, Lung, and Blood Institute, Bethesda, Maryland
Role of PDE3B in Regulation of Energy Homeostasis

1:00-1:30 pm

Concluding Remarks

1:30-2:30 pm

Poster Viewing

(Posters to be removed by 3 pm)

Return to International Workshop on Phosphodiesterases (PDE2009) main page.

Last Updated Date: 11/30/2012
Last Reviewed Date: 11/30/2012
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology