June 7-9, 2009
Agenda
Day 1: Monday, June 8, 2009
Day 2: Tuesday, June 9, 2009
For more details on individual speakers, see the conference roster.
Day 1: Monday, June 8, 2009
9:00-9:45 am |
Introductory Lecture: GNAS Mutations and Endocrine Disorders
L.S. Weinstein
National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland |
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9:45-10 am |
Break |
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Session I
PKA: Structure and Function and Insight from Human Disease and Mice
10:00-10:30 am |
S. Taylor
University of California, San Diego, California
Title of talk: TBA |
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10:30-11:00 am |
K. Taskén
University of Oslo, Norway
AKAP specificity and spatial dynamic of PKA regulatory subunits |
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11:00-11:30 am |
C. Stratakis
Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland
Insight on cAMP pathway dysregulation in endocrine tumors from the study of PRKAR1A mutations |
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11:30 am-12:00 pm |
Break (Poster Viewing) |
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12-12:30 pm |
L. Kirschner
Ohio State University, Columbus, Ohio
Insight on PKA from PRKAR1A targeted inactivation in transgenic mice |
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12:30-1:00 pm |
A. Lania
University of Milan, Italy
Expression and function of PKA regulatory units in endocrine-related tissues |
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1:00-1:30 pm |
G. Langsley
Faculté de Médecine Paris Descartes - Hôpital Cochin, Paris, France
AMP-dependent protein kinase in infectious diseases |
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1:30-2:30 pm |
Lunch Break (Poster Viewing) |
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Session IIA
GNAS Locus: Structure and Function
2:30-3:00 pm |
G. Kelsey
The Babraham Institute, Cambridge, United Kingdom
Imprinted genes and energy homeostasis |
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3:00-3:30 pm |
H. Jüppner
Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts
The GNAS locus and Pseudohyporathyroidism |
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3:30- 4:00 pm |
P. Bianco
La Sapienza University, Rome, Italy
GNAS transcripts in skeletal progenitors |
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4:00-4:30 pm |
Break (Poster Viewing) |
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Session IIB
Human Diseases Associated with GNAS Mutations
4:30-5:00 pm |
G. Mantovani
University of Milan, Italy
Clinical and laboratory findings in patients with epigenetic defects at the GNAS locus |
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5:00-5:30 pm |
Eileen Shore
The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Diagnostic and mutational spectrum of progressive osseous heteroplasia (POH) and other forms of GNAS-based heterotopic ossification |
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5:30- 6:00 pm |
K. Freson
University of Leuven, Leuven, Belgium
XLalpha, its cofactor ALEX and blood platelet function |
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7:00 pm–10:00 |
Dinner |
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Day 2: Tuesday, June 9, 2009
Session IIIA
PDEs: Structure and Function
9:00-9:30 am |
M. Conti
University of California, San Francisco, California
Cyclic Nucleotide Phosphodiesterases: Molecular Regulation |
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9:30-10:00 am |
G. Vandecasteele
Faculté de Pharmacie, Châtenay-Malabry Cedex, France
Spatiotemporal dynamics of cAMP signals: lessons from myocytes |
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10:00-10:30 am |
M.D. Houslay
University of Glasgow, Glasgow, Scotland, United Kingdom
PDEs in cAMP cell signalling compartimentalization |
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10:30-11:00 am |
Break (Poster Viewing) |
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Session IIIB
PDEs in Human Diseases
11:00-11:30 am |
J. Bertherat
Institute Cochin, Paris, France
Genetics of Phosphodiesterase 11A in patients with ACTH independent adrenocortical lesions |
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11:30 am-12:00 pm |
A. Horvath
Eunice Kennedy Shriver National Institute of Child Health & Human Development, Bethesda, Maryland
PDE8B, PDE7A and other cAMP-binding PDEs and endocrine tumorigenesis |
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12:00-12:30 pm |
Dr. J. Beavo
University of Washington, Seattle, Washington
PDE as therapeutical targets |
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12:30-1:00pm |
Dr. V. Manganiello
National Heart, Lung, and Blood Institute, Bethesda, Maryland
Role of PDE3B in Regulation of Energy Homeostasis |
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1:00-1:30 pm |
Concluding Remarks |
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1:30-2:30 pm |
Poster Viewing
(Posters to be removed by 3 pm) |
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